A multicenter, randomized, double-blind, controlled study to evaluate the efficacy and safety of dantrolene on ventricular arrhythmia as well as mortality and morbidity in patients with chronic heart failure (SHO-IN trial): rationale and design
Kobayashi, Shigeki, Wakeyama, Takatoshi, Ono, Shiro, Ikeda, Yasuhiro, Omura, Masato, Oda, Tsuyoshi, Hisamatsu, Yuji, Seki, Kozaburo, Satoh, Akira, Hiromoto, Mitsuyuki, Akashi, Shintaro, Uchida, Kosuke, Harada, Masahiko, Furutani, Yuhji, Nakamura, Yasuma, Kohno, Masateru, Kawamura, Shuji, Obayashi, Masakazu, Michishige, Hiroyuki, Yano, Masafumi
Published in Journal of cardiology (01.04.2020)
Published in Journal of cardiology (01.04.2020)
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FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure
YANO, Masafumi, KOBAYASHI, Shigeki, KOHNO, Michihiro, MATSUZAKI, Masunori, KOHNO, Masateru, DOI, Masahiro, TOKUHISA, Takahiro, OKUDA, Shinichi, SUETSUGU, Masae, HISAOKA, Takayuki, OBAYASHI, Masakazu, OHKUSA, Tomoko
Published in Circulation (New York, N.Y.) (28.01.2003)
Published in Circulation (New York, N.Y.) (28.01.2003)
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Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca2+ leak through ryanodine receptor in heart failure
YANO, Masafumi, ONO, Kaoru, NOGUCHI, Naoya, TAKASAWA, Shin, OKAMOTO, Hiroshi, MATSUZAKI, Masunori, OHKUSA, Tomoko, SUETSUGU, Masae, KOHNO, Masateru, HISAOKA, Takayuki, KOBAYASHI, Shigeki, HISAMATSU, Yuji, YAMAMOTO, Takeshi, KOHNO, Michihiro
Published in Circulation (New York, N.Y.) (24.10.2000)
Published in Circulation (New York, N.Y.) (24.10.2000)
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Propranolol prevents the development of heart failure by restoring FKBp12.6-mediated stabilization of ryanodine receptor
DOI, Masahiro, YANO, Masafumi, MATSUZAKI, Masunori, KOBAYASHI, Shigeki, KOHNO, Masateru, TOKUHISA, Takahiro, OKUDA, Shinichi, SUETSUGU, Masae, HISAMATSU, Yuhji, OHKUSA, Tomoko, KOHNO, Michihiro
Published in Circulation (New York, N.Y.) (19.03.2002)
Published in Circulation (New York, N.Y.) (19.03.2002)
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A new cardioprotective agent, JTV519, improves defective channel gating of ryanodine receptor in heart failure
Kohno, Masateru, Yano, Masafumi, Kobayashi, Shigeki, Doi, Masahiro, Oda, Tetsuro, Tokuhisa, Takahiro, Okuda, Shinichi, Ohkusa, Tomoko, Kohno, Michihiro, Matsuzaki, Masunori
Published in American journal of physiology. Heart and circulatory physiology (01.03.2003)
Published in American journal of physiology. Heart and circulatory physiology (01.03.2003)
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Journal Article
Effect of milrinone on left ventricular relaxation and Ca2+ uptake function of cardiac sarcoplasmic reticulum
Yano, Masafumi, Kohno, Michihiro, Ohkusa, Tomoko, Mochizuki, Mamoru, Yamada, Jutaro, Kohno, Masateru, Hisaoka, Takayuki, Ono, Kaoru, Tanigawa, Taketo, Kobayashi, Shigeki, Matsuzaki, Masunori
Published in American journal of physiology. Heart and circulatory physiology (01.10.2000)
Published in American journal of physiology. Heart and circulatory physiology (01.10.2000)
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Journal Article
Impact of the Cross-Sectional Geometry of the Post-Deployment Coronary Stent on In-Stent Neointimal Hyperplasia: An Intravascular Ultrasound Study
Murata, Takashige, Hiro, Takafumi, Fujii, Takashi, Yasumoto, Kyounori, Murashige, Akihiro, Kohno, Masateru, Yamada, Jyutaro, Miura, Toshiro, Matsuzaki, Masunori
Published in Circulation Journal (2002)
Published in Circulation Journal (2002)
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Journal Article
Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure
Yano, M, Ono, K, Ohkusa, T, Suetsugu, M, Kohno, M, Hisaoka, T, Kobayashi, S, Hisamatsu, Y, Yamamoto, T, Noguchi, N, Takasawa, S, Okamoto, H, Matsuzaki, M
Published in Circulation (New York, N.Y.) (24.10.2000)
Published in Circulation (New York, N.Y.) (24.10.2000)
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Journal Article
Altered interaction of FKBP12.6 with ryanodine receptor as a cause of abnormal Ca(2+) release in heart failure
Ono, K, Yano, M, Ohkusa, T, Kohno, M, Hisaoka, T, Tanigawa, T, Kobayashi, S, Matsuzaki, M
Published in Cardiovascular research (01.11.2000)
Published in Cardiovascular research (01.11.2000)
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Valsartan restores sarcoplasmic reticulum function with no appreciable effect on resting cardiac function in pacing-induced heart failure
OKUDA, Shinichi, YANO, Masafumi, DOI, Masahiro, ODA, Tetsuro, TOKUHISA, Takahiro, KOHNO, Masateru, KOBAYASHI, Shigeki, YAMAMOTO, Takeshi, OHKUSA, Tomoko, MATSUZAKI, Masunori
Published in Circulation (New York, N.Y.) (24.02.2004)
Published in Circulation (New York, N.Y.) (24.02.2004)
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Journal Article
Altered interaction of FKBP12.6 with ryanodine receptor as a cause of abnormal Ca2+ release in heart failure
Ono, Kaoru, Yano, Masafumi, Ohkusa, Tomoko, Kohno, Masateru, Hisaoka, Takayuki, Tanigawa, Taketo, Kobayashi, Shigeki, Kohno, Michihuro, Matsuzaki, Masunori
Published in Cardiovascular research (01.11.2000)
Published in Cardiovascular research (01.11.2000)
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Journal Article
Effect of milrinone on left ventricular relaxation and Ca(2+) uptake function of cardiac sarcoplasmic reticulum
Yano, M, Kohno, M, Ohkusa, T, Mochizuki, M, Yamada, J, Hisaoka, T, Ono, K, Tanigawa, T, Kobayashi, S, Matsuzaki, M
Published in American journal of physiology. Heart and circulatory physiology (01.10.2000)
Published in American journal of physiology. Heart and circulatory physiology (01.10.2000)
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Journal Article
Enhancement of Rho/Rho-kinase system in regulation of vascular smooth muscle contraction in tachycardia-induced heart failure
HISAOKA, Takayuki, YANO, Masafumi, OHKUSA, Tomoko, SUETSUGU, Masae, ONO, Kaoru, KOHNO, Masateru, YAMADA, Jyutaro, KOBAYASHI, Shigeki, KOHNO, Michihiro, MATSUZAKI, Masunori
Published in Cardiovascular research (01.02.2001)
Published in Cardiovascular research (01.02.2001)
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Journal Article
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Kabumoto, Masaaki, Minagawa, Yoshihisa, Hirasawa, Kanako, Kurita, Masahiro, Kohno, Masateru, Hamamura, Toshihiro, Hibi, Shoichi
Year of Publication 06.12.2022
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Year of Publication 06.12.2022
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Kabumoto, Masaaki, Minagawa, Yoshihisa, Hirasawa, Kanako, Kurita, Masahiro, Kohno, Masateru, Hamamura, Toshihiro, Hibi, Shoichi
Year of Publication 28.06.2022
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Year of Publication 28.06.2022
Patent
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Kabumoto, Masaaki, Minagawa, Yoshihisa, Hirasawa, Kanako, Kurita, Masahiro, Kohno, Masateru, Hamamura, Toshihiro, Hibi, Shoichi
Year of Publication 21.06.2022
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Year of Publication 21.06.2022
Patent
A new cardioprotective agent, JTV519, improves defective channel gating of ryanodine receptor in heart failure
KOHNO, Masateru, YANO, Masafumi, KOBAYASHI, Shigeki, DOI, Masahiro, ODA, Tetsuro, TOKUHISA, Takahiro, OKUDA, Shinichi, OHKUSA, Tomoko, KOHNO, Michihiro, MATSUZAKI, Masunori
Published in American journal of physiology. Heart and circulatory physiology (01.03.2003)
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Published in American journal of physiology. Heart and circulatory physiology (01.03.2003)
Journal Article
Low dose of propranolol prevents the development of heart failure by restoring the defective interaction of FKBP12.6 with cardiac ryanodine receptor
Doi, Masahiro, Yano, Masafumi, Kobayashi, Shigeki, Kohno, Masateru, Suetsugu, Masae, Tokuhisa, Takahiro, Okuda, Shin-ichi, Ohkusa, Tomoko, Kohno, Michihiro, Matsuzaki, Masunori
Published in Journal of the American College of Cardiology (06.03.2002)
Published in Journal of the American College of Cardiology (06.03.2002)
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Journal Article
O-4 Valsartan restores normal FKBP12.6-RYK interaction by a strong inhibition of PKA-mediated hyperphosphorylation of RYR in heart failure
Okuda, Shinichi, Yano, Masafumi, Kobayashi, Shigeki, Doi, Masahiro, Kohno, Masateru, Yamamoto, Takeshi, Oda, Tetsuro, Tokuhisa, Takahiro, Suetsugu, Masae, Ohkusa, Tomoko, Matsuzaki, Masunori
Published in Journal of molecular and cellular cardiology (01.10.2002)
Published in Journal of molecular and cellular cardiology (01.10.2002)
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