Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs
Jost, Norbert, Virág, László, Comtois, Philippe, Ördög, Balázs, Szuts, Viktória, Seprényi, György, Bitay, Miklós, Kohajda, Zsófia, Koncz, István, Nagy, Norbert, Szél, Tamás, Magyar, János, Kovács, Mária, Puskás, László G., Lengyel, Csaba, Wettwer, Erich, Ravens, Ursula, Nánási, Péter P., Papp, Julius Gy, Varró, András, Nattel, Stanley
Published in The Journal of physiology (01.09.2013)
Published in The Journal of physiology (01.09.2013)
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The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments
Kohajda, Zsófia, Farkas-Morvay, Nikolett, Jost, Norbert, Nagy, Norbert, Geramipour, Amir, Horváth, András, Varga, Richárd S, Hornyik, Tibor, Corici, Claudia, Acsai, Károly, Horváth, Balázs, Prorok, János, Ördög, Balázs, Déri, Szilvia, Tóth, Dániel, Levijoki, Jouko, Pollesello, Piero, Koskelainen, Tuula, Otsomaa, Leena, Tóth, András, Baczkó, István, Leprán, István, Nánási, Péter P, Papp, Julius Gy, Varró, András, Virág, László
Published in PloS one (10.11.2016)
Published in PloS one (10.11.2016)
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The Properties of the Transient Outward, Inward Rectifier and Acetylcholine-Sensitive Potassium Currents in Atrial Myocytes from Dogs in Sinus Rhythm and Experimentally Induced Atrial Fibrillation Dog Models
Kohajda, Zsófia, Corici, Claudia, Kristóf, Attila, Virág, László, Husti, Zoltán, Baczkó, István, Sághy, László, Varró, András, Jost, Norbert
Published in Pharmaceuticals (Basel, Switzerland) (29.08.2024)
Published in Pharmaceuticals (Basel, Switzerland) (29.08.2024)
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A Comparative Study of the Rapid (I Kr ) and Slow (I Ks ) Delayed Rectifier Potassium Currents in Undiseased Human, Dog, Rabbit, and Guinea Pig Cardiac Ventricular Preparations
Ágoston, Márta, Kohajda, Zsófia, Virág, László, Baláti, Beáta, Nagy, Norbert, Lengyel, Csaba, Bitay, Miklós, Bogáts, Gábor, Vereckei, András, Papp, Julius Gy, Varró, András, Jost, Norbert
Published in Pharmaceuticals (Basel, Switzerland) (20.08.2024)
Published in Pharmaceuticals (Basel, Switzerland) (20.08.2024)
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The Inhibition of the Small-Conductance Ca2+-Activated Potassium Channels Decreases the Sinus Node Pacemaking during Beta-Adrenergic Activation
Bitay, Gergő, Tóth, Noémi, Déri, Szilvia, Szlovák, Jozefina, Kohajda, Zsófia, Varró, András, Nagy, Norbert
Published in Pharmaceuticals (Basel, Switzerland) (04.03.2022)
Published in Pharmaceuticals (Basel, Switzerland) (04.03.2022)
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Cardiac electrophysiological remodeling associated with enhanced arrhythmia susceptibility in a canine model of elite exercise
Polyák, Alexandra, Topal, Leila, Zombori-Tóth, Noémi, Tóth, Noémi, Prorok, János, Kohajda, Zsófia, Déri, Szilvia, Demeter-Haludka, Vivien, Hegyi, Péter, Venglovecz, Viktória, Ágoston, Gergely, Husti, Zoltán, Gazdag, Péter, Szlovák, Jozefina, Árpádffy-Lovas, Tamás, Naveed, Muhammad, Sarusi, Annamária, Jost, Norbert, Virág, László, Nagy, Norbert, Baczkó, István, Farkas, Attila S, Varró, András
Published in eLife (23.02.2023)
Published in eLife (23.02.2023)
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Journal Article
Novel Na+/Ca2+ Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na+/Ca2+ Exchanger in Pacemaking of Rabbit Sinus Node Tissue
Kohajda, Zsófia, Tóth, Noémi, Szlovák, Jozefina, Loewe, Axel, Bitay, Gergő, Gazdag, Péter, Prorok, János, Jost, Norbert, Levijoki, Jouko, Pollesello, Piero, Papp, Julius Gy, Varró, András, Nagy, Norbert
Published in Frontiers in pharmacology (29.01.2020)
Published in Frontiers in pharmacology (29.01.2020)
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Muscarinic agonists inhibit the ATP-dependent potassium current and suppress the ventricle-Purkinje action potential dispersion
Magyar, Tibor, Árpádffy-Lovas, Tamás, Pászti, Bence, Tóth, Noémi, Szlovák, Jozefina, Gazdag, Péter, Kohajda, Zsófia, Gyökeres, András, Györe, Balázs, Gurabi, Zsolt, Jost, Norbert, Virág, László, Papp, Julius Gy, Nagy, Norbert, Koncz, István
Published in Canadian journal of physiology and pharmacology (01.02.2021)
Published in Canadian journal of physiology and pharmacology (01.02.2021)
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Diclofenac prolongs repolarization in ventricular muscle with impaired repolarization reserve
Kristóf, Attila, Husti, Zoltán, Koncz, István, Kohajda, Zsófia, Szél, Tamás, Juhász, Viktor, Biliczki, Péter, Jost, Norbert, Baczkó, István, Papp, Julius Gy, Varró, András, Virág, László
Published in PloS one (31.12.2012)
Published in PloS one (31.12.2012)
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L-364,373 (R-L3) enantiomers have opposite modulating effects on IKs in mammalian ventricular myocytes
Corici, Claudia, Kohajda, Zsófia, Kristóf, Attila, Horváth, András, Virág, László, Szél, Tamás, Nagy, Norbert, Szakonyi, Zsolt, Fülöp, Ferenc, Muntean, Danina M, Varró, András, Jost, Norbert
Published in Canadian journal of physiology and pharmacology (01.08.2013)
Published in Canadian journal of physiology and pharmacology (01.08.2013)
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The development of L-type Ca2+ current mediated alternans does not depend on the restitution slope in canine ventricular myocardium
Tóth, Noémi, Szlovák, Jozefina, Kohajda, Zsófia, Bitay, Gergő, Veress, Roland, Horváth, Balázs, Papp, Julius Gy, Varró, András, Nagy, Norbert
Published in Scientific reports (17.08.2021)
Published in Scientific reports (17.08.2021)
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The reverse mode of the Na+/Ca2+ exchanger contributes to the pacemaker mechanism in rabbit sinus node cells
Tóth, Noémi, Loewe, Axel, Szlovák, Jozefina, Kohajda, Zsófia, Bitay, Gergő, Levijoki, Jouko, Papp, Julius Gy, Varró, András, Nagy, Norbert
Published in Scientific reports (17.12.2022)
Published in Scientific reports (17.12.2022)
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Evaluation of Possible Proarrhythmic Potency: Comparison of the Effect of Dofetilide, Cisapride, Sotalol, Terfenadine, and Verapamil on hERG and Native I Kr Currents and on Cardiac Action Potential
Orvos, Péter, Kohajda, Zsófia, Szlovák, Jozefina, Gazdag, Péter, Árpádffy-Lovas, Tamás, Tóth, Dániel, Geramipour, Amir, Tálosi, László, Jost, Norbert, Varró, András, Virág, László
Published in Toxicological sciences (01.04.2019)
Published in Toxicological sciences (01.04.2019)
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Increased Ca2+ content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete’s heart model
Gazdag, Péter, Oravecz, Kinga, Acsai, Károly, Demeter-Haludka, Vivien, Ördög, Balázs, Szlovák, Jozefina, Kohajda, Zsófia, Polyák, Alexandra, Barta, Bálint András, Oláh, Attila, Radovits, Tamás, Merkely, Béla, Papp, Julius Gy, Baczkó, István, Varró, András, Nagy, Norbert, Prorok, János
Published in Scientific reports (11.11.2020)
Published in Scientific reports (11.11.2020)
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Journal Article
Author Correction: Increased Ca2+ content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete’s heart model
Gazdag, Péter, Oravecz, Kinga, Acsai, Károly, Demeter‑Haludka, Vivien, Ördög, Balázs, Szlovák, Jozefina, Kohajda, Zsófia, Polyák, Alexandra, Barta, Bálint András, Oláh, Attila, Radovits, Tamás, Merkely, Béla, Papp, Julius Gy, Baczkó, István, Varró, András, Nagy, Norbert, Prorok, János
Published in Scientific reports (04.06.2021)
Published in Scientific reports (04.06.2021)
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Journal Article
Selective Na(+) /Ca(2+) exchanger inhibition prevents Ca(2+) overload-induced triggered arrhythmias
Nagy, Norbert, Kormos, Anita, Kohajda, Zsófia, Szebeni, Áron, Szepesi, Judit, Pollesello, Piero, Levijoki, Jouko, Acsai, Károly, Virág, László, Nánási, Péter P, Papp, Julius Gy, Varró, András, Tóth, András
Published in British journal of pharmacology (01.12.2014)
Published in British journal of pharmacology (01.12.2014)
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Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity
Otsomaa, Leena, Levijoki, Jouko, Wohlfahrt, Gerd, Chapman, Hugh, Koivisto, Ari‐Pekka, Syrjänen, Kaisa, Koskelainen, Tuula, Peltokorpi, Saara‐Elisa, Finckenberg, Piet, Heikkilä, Aira, Abi‐Gerges, Najah, Ghetti, Andre, Miller, Paul E., Page, Guy, Mervaala, Eero, Nagy, Norbert, Kohajda, Zsófia, Jost, Norbert, Virág, László, Varró, András, Papp, Julius Gy
Published in British journal of pharmacology (01.12.2020)
Published in British journal of pharmacology (01.12.2020)
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A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant‐negative mutation of the KCNE1 gene
Major, Péter, Baczkó, István, Hiripi, László, Odening, Katja E., Juhász, Viktor, Kohajda, Zsófia, Horváth, András, Seprényi, György, Kovács, Mária, Virág, László, Jost, Norbert, Prorok, János, Ördög, Balázs, Doleschall, Zoltán, Nattel, Stanley, Varró, András, Bősze, Zsuzsanna
Published in British journal of pharmacology (01.06.2016)
Published in British journal of pharmacology (01.06.2016)
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The Cardiac Pacemaker Story—Fundamental Role of the Na+/Ca2+ Exchanger in Spontaneous Automaticity
Kohajda, Zsófia, Loewe, Axel, Tóth, Noémi, Varró, András, Nagy, Norbert
Published in Frontiers in pharmacology (28.04.2020)
Published in Frontiers in pharmacology (28.04.2020)
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Journal Article
Selective Na+/Ca2+ exchanger inhibition prevents Ca2+ overload‐induced triggered arrhythmias
Nagy, Norbert, Kormos, Anita, Kohajda, Zsófia, Szebeni, Áron, Szepesi, Judit, Pollesello, Piero, Levijoki, Jouko, Acsai, Károly, Virág, László, Nánási, Péter P, Papp, Julius Gy, Varró, András, Tóth, András
Published in British journal of pharmacology (01.12.2014)
Published in British journal of pharmacology (01.12.2014)
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