Intratracheal and oral administration of SM‐276001: A selective TLR7 agonist, leads to antitumor efficacy in primary and metastatic models of cancer
Koga‐Yamakawa, Erina, Dovedi, Simon J., Murata, Masashi, Matsui, Hiroyuki, Leishman, Andrew J., Bell, John, Ferguson, Douglas, Heaton, Simon P., Oki, Toshihiro, Tomizawa, Hideyuki, Bahl, Ash, Takaku, Haruo, Wilkinson, Robert W., Harada, Hideyuki
Published in International journal of cancer (01.02.2013)
Published in International journal of cancer (01.02.2013)
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Journal Article
DSP-0509, a systemically available TLR7 agonist, exhibits combination effect with immune checkpoint blockade by activating anti-tumor immune effects
Ota, Yosuke, Nagai, Yasuhiro, Hirose, Yuko, Hori, Seiji, Koga-Yamakawa, Erina, Eguchi, Ken, Sumida, Kentaro, Murata, Masashi, Umehara, Hiroki, Yamamoto, Setsuko
Published in Frontiers in immunology (30.01.2023)
Published in Frontiers in immunology (30.01.2023)
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Journal Article
Synthesis of Novel Benzo-Fused Heteroaryl Derivatives as Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitors
Komiya, Masafumi, Asano, Shigehiro, Koike, Nobuyuki, Koga, Erina, Igarashi, Junetsu, Nakatani, Shogo, Isobe, Yoshiaki
Published in Chemical & pharmaceutical bulletin (2013)
Published in Chemical & pharmaceutical bulletin (2013)
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Journal Article
Double-Modification of Lectin Using Two Distinct Chemistries for Fluorescent Ratiometric Sensing and Imaging Saccharides in Test Tube or in Cell
Nakata, Eiji, Koshi, Yoichiro, Koga, Erina, Katayama, Yoshiki, Hamachi, Itaru
Published in Journal of the American Chemical Society (28.09.2005)
Published in Journal of the American Chemical Society (28.09.2005)
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Journal Article
Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype
Motomura, Takashi, Koga, Erina, Taketomi, Akinobu, Fukuhara, Takasuke, Mano, Yohei, Muto, Jun, Konishi, Hideyuki, Toshima, Takeo, Uchiyama, Hideaki, Yoshizumi, Tomoharu, Shirabe, Ken, Maehara, Yoshihiko
Published in Hepatology research (01.03.2012)
Published in Hepatology research (01.03.2012)
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Journal Article
TLR7 tolerance is independent of the type I IFN pathway and leads to loss of anti-tumor efficacy in mice
Koga-Yamakawa, Erina, Murata, Masashi, Dovedi, Simon J., Wilkinson, Robert W., Ota, Yosuke, Umehara, Hiroki, Sugaru, Eiji, Hirose, Yuko, Harada, Hideyuki, Jewsbury, Philip J., Yamamoto, Setsuko, Robinson, David T., Li, Chiang J.
Published in Cancer Immunology, Immunotherapy (01.10.2015)
Published in Cancer Immunology, Immunotherapy (01.10.2015)
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Journal Article
A novel systemically administered toll‐like receptor 7 agonist potentiates the effect of ionizing radiation in murine solid tumor models
Adlard, Amy L., Dovedi, Simon J., Telfer, Brian A., Koga‐Yamakawa, Erina, Pollard, Charlotte, Honeychurch, Jamie, Illidge, Timothy M., Murata, Masashi, Robinson, David T., Jewsbury, Philip J., Wilkinson, Robert W., Stratford, Ian J.
Published in International journal of cancer (15.08.2014)
Published in International journal of cancer (15.08.2014)
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Journal Article
Multicenter, Open-Label, Phase I Study of DSP-7888 Dosing Emulsion in Patients with Advanced Malignancies
Spira, Alexander, Hansen, Aaron R., Harb, Wael A., Curtis, Kelly K., Koga-Yamakawa, Erina, Origuchi, Makoto, Li, Zhonggai, Ertik, Bella, Shaib, Walid L.
Published in Targeted oncology (01.07.2021)
Published in Targeted oncology (01.07.2021)
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Journal Article
Arabino-mycolates derived from cell-wall skeleton of Mycobacterium bovis BCG as a prominent structure for recognition by host immunity
Miyauchi, Masanori, Murata, Masashi, Shibuya, Keiko, Koga-Yamakawa, Erina, Uenishi, Yuko, Kusunose, Naoto, Sunagawa, Makoto, Yano, Ikuya, Kashiwazaki, Yasuo
Published in Drug Discoveries & Therapeutics (01.01.2011)
Published in Drug Discoveries & Therapeutics (01.01.2011)
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Journal Article
Abstract 5480: Colorectal cancer cell lines harboring mutation in Wnt/β-catenin pathway shows enhanced sensitivity to the stearoyl-CoA desaturase (SCD) inhibitor, DSP-0692
Furuta, Yudai, Fukunaga, Yuichi, Ikeda, Satoshi, Koga, Erina, Umehara, Hiroki, Otsubo, Tsuguteru, Watanabe, Manabu, Hasegawa, Futoshi, Ban, Hitoshi, Sugaru, Eiji
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Synthesis and structure based optimization of 2-(4-phenoxybenzoyl)-5-hydroxyindole as a novel CaMKII inhibitor
Komiya, Masafumi, Asano, Shigehiro, Koike, Nobuyuki, Koga, Erina, Igarashi, Junetsu, Nakatani, Shogo, Isobe, Yoshiaki
Published in Bioorganic & medicinal chemistry (01.12.2012)
Published in Bioorganic & medicinal chemistry (01.12.2012)
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Journal Article
Abstract LB-069: In vivo delivery of asymmetric gene-silencing RNAs targeting CTNNB1 and PD-L1 show a broad spectrum of potent antitumor activities in preclinical cancer models
Li, Youzhi, Gao, Yuan, Wang, Yuxin, Su, Jie, Hsu, Eric, Wybieralska, Ewa, Huang, Janet, Gada, Keyur, Oishi, Jun, Dai, Xiaoshu, Koga, Erina, Li, Wei, Sun, Xiangao, Brooks, Emily, Li, Chiang J.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Complete resection of unicentric Castleman disease in the superior mediastinum: A case report
Haro, Akira, Koga, Erina, Fukuyama, Yasuro
Published in International journal of surgery case reports (01.01.2016)
Published in International journal of surgery case reports (01.01.2016)
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Journal Article
Abstract 2571: Sustained induction of TRAIL and granzyme B as well as intratumor infiltration of cytotoxic T lymphocytes (CTL) by a novel TLR7 agonist, DSR-6434, after systemic administration
Inagaki, Ryosaku, Aoki, Mikio, Kimura, Toru, Hirose, Yuko, Umehara, Hiroki, Koga, Erina, Murata, Masashi, Wilkinson, Robert W., Robinson, David T., Jewsbury, Philip J., Li, Chiang J.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidines as novel class of potent and highly selective CaMKII inhibitors
Asano, Shigehiro, Komiya, Masafumi, Koike, Nobuyuki, Koga, Erina, Nakatani, Shogo, Isobe, Yoshiaki
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Journal Article
Structure and activity relationship of 2-(substituted benzoyl)-hydroxyindoles as novel CaMKII inhibitors
Komiya, Masafumi, Asano, Shigehiro, Koike, Nobuyuki, Koga, Erina, Igarashi, Junetsu, Nakatani, Shogo, Isobe, Yoshiaki
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
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Journal Article
Phagocytosis plays a dual role in activating dendritic cells; digestive production of active Toll-like receptor ligands and cooperation with Toll-like receptor signaling
Miyauchi, M, Murata, M, Shibuya, K, Koga-Yamakawa, E, Yanagawa, Y, Azuma, I, Kashiwazaki, Y
Published in Drug discoveries & therapeutics (01.04.2010)
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Published in Drug discoveries & therapeutics (01.04.2010)
Journal Article
Abstract 4726: Novel intravenous injectable TLR7 agonist, DSP-0509, synergistically enhanced antitumor immune responses in combination with anti-PD-1 antibody
Ota, Yosuke, Otsubo, Takeshi, Koroki, Junya, Hirose, Yuko, Koga-Yamakawa, Erina, Murata, Masashi, Goto, Masashi, Matsuki, Yasushi
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy
Dovedi, Simon J, Adlard, Amy L, Ota, Yosuke, Murata, Masashi, Sugaru, Eiji, Koga-Yamakawa, Erina, Eguchi, Ken, Hirose, Yuko, Yamamoto, Setsuko, Umehara, Hiroki, Honeychurch, Jamie, Cheadle, Eleanor J, Hughes, Gareth, Jewsbury, Philip J, Wilkinson, Robert W, Stratford, Ian J, Illidge, Timothy M
Published in Oncotarget (29.03.2016)
Published in Oncotarget (29.03.2016)
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Journal Article
Abstract 2567: Enhancement of antitumor activity of DSP-6434, a novel TLR7 agonist through reduction of TLR tolerance
Koga-Yamakawa, Erina, Murata, Masashi, Dovedi, Simon J., Wilkinson, Robert W., Umehara, Hiroki, Sugaru, Eiji, Hirose, Yuko, Harada, Hideyuki, Robinson, David T., Jewsbury, Philip J., Yamamoto, Setsuko, Li, Chiang J.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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