TRPM channels in health and disease
Chubanov, Vladimir, Köttgen, Michael, Touyz, Rhian M, Gudermann, Thomas
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Published in Nature reviews. Nephrology (01.03.2024)
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Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner
Peintner, Lukas, Venkatraman, Anusha, Waeldin, Astrid, Hofherr, Alexis, Busch, Tilman, Voronov, Alexander, Viau, Amandine, Kuehn, E. Wolfgang, Köttgen, Michael, Borner, Christoph
Published in Autophagy (02.09.2021)
Published in Autophagy (02.09.2021)
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Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state
Tosic, Jelena, Kim, Gwang-Jin, Pavlovic, Mihael, Schröder, Chiara M., Mersiowsky, Sophie-Luise, Barg, Margareta, Hofherr, Alexis, Probst, Simone, Köttgen, Michael, Hein, Lutz, Arnold, Sebastian J.
Published in Nature cell biology (01.12.2019)
Published in Nature cell biology (01.12.2019)
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Identification of a Urate Transporter, ABCG2, with a Common Functional Polymorphism Causing Gout
Woodward, Owen M., Köttgen, Anna, Coresh, Josef, Boerwinkle, Eric, Guggino, William B., Köttgen, Michael, Burg, Maurice B.
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2009)
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Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans
Schlosser, Pascal, Li, Yong, Sekula, Peggy, Raffler, Johannes, Grundner-Culemann, Franziska, Pietzner, Maik, Cheng, Yurong, Wuttke, Matthias, Steinbrenner, Inga, Schultheiss, Ulla T., Kotsis, Fruzsina, Kacprowski, Tim, Forer, Lukas, Hausknecht, Birgit, Ekici, Arif B., Nauck, Matthias, Völker, Uwe, Walz, Gerd, Oefner, Peter J., Kronenberg, Florian, Mohney, Robert P., Köttgen, Michael, Suhre, Karsten, Eckardt, Kai-Uwe, Kastenmüller, Gabi, Köttgen, Anna
Published in Nature genetics (01.02.2020)
Published in Nature genetics (01.02.2020)
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Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition
Hofherr, Alexis, Wagner, Claudius J., Watnick, Terry, Köttgen, Michael
Published in Kidney international (01.04.2016)
Published in Kidney international (01.04.2016)
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Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney
Viau, Amandine, Bienaimé, Frank, Lukas, Kamile, Todkar, Abhijeet P, Knoll, Manuel, Yakulov, Toma A, Hofherr, Alexis, Kretz, Oliver, Helmstädter, Martin, Reichardt, Wilfried, Braeg, Simone, Aschman, Tom, Merkle, Annette, Pfeifer, Dietmar, Dumit, Verónica I, Gubler, Marie‐Claire, Nitschke, Roland, Huber, Tobias B, Terzi, Fabiola, Dengjel, Jörn, Grahammer, Florian, Köttgen, Michael, Busch, Hauke, Boerries, Melanie, Walz, Gerd, Triantafyllopoulou, Antigoni, Kuehn, E Wolfgang
Published in The EMBO journal (01.08.2018)
Published in The EMBO journal (01.08.2018)
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Primary cilia regulate mTORC1 activity and cell size through Lkb1
Kuehn, E. Wolfgang, Boehlke, Christopher, Kotsis, Fruzsina, Patel, Vishal, Braeg, Simone, Voelker, Henriette, Bredt, Saskia, Beyer, Theresa, Janusch, Heike, Hamann, Christoph, Gödel, Markus, Müller, Klaus, Herbst, Martin, Hornung, Miriam, Doerken, Mara, Köttgen, Michael, Nitschke, Roland, Igarashi, Peter, Walz, Gerd
Published in Nature cell biology (01.11.2010)
Published in Nature cell biology (01.11.2010)
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Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine
Schlosser, Pascal, Scherer, Nora, Grundner-Culemann, Franziska, Monteiro-Martins, Sara, Haug, Stefan, Steinbrenner, Inga, Uluvar, Burulça, Wuttke, Matthias, Cheng, Yurong, Ekici, Arif B., Gyimesi, Gergely, Karoly, Edward D., Kotsis, Fruzsina, Mielke, Johanna, Gomez, Maria F., Yu, Bing, Grams, Morgan E., Coresh, Josef, Boerwinkle, Eric, Köttgen, Michael, Kronenberg, Florian, Meiselbach, Heike, Mohney, Robert P., Akilesh, Shreeram, Schmidts, Miriam, Hediger, Matthias A., Schultheiss, Ulla T., Eckardt, Kai-Uwe, Oefner, Peter J., Sekula, Peggy, Li, Yong, Köttgen, Anna
Published in Nature genetics (01.06.2023)
Published in Nature genetics (01.06.2023)
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Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2
Cabezas, Oscar Rubio, Flanagan, Sarah E, Stanescu, Horia, García-Martínez, Elena, Caswell, Richard, Lango-Allen, Hana, Antón-Gamero, Montserrat, Argente, Jesús, Bussell, Anna-Marie, Brandli, Andre, Cheshire, Chris, Crowne, Elizabeth, Dumitriu, Simona, Drynda, Robert, Hamilton-Shield, Julian P, Hayes, Wesley, Hofherr, Alexis, Iancu, Daniela, Issler, Naomi, Jefferies, Craig, Jones, Peter, Johnson, Matthew, Kesselheim, Anne, Klootwijk, Enriko, Koettgen, Michael, Lewis, Wendy, Martos, José María, Mozere, Monika, Norman, Jill, Patel, Vaksha, Parrish, Andrew, Pérez-Cerdá, Celia, Pozo, Jesús, Rahman, Sofia A, Sebire, Neil, Tekman, Mehmet, Turnpenny, Peter D, Hoff, William Van't, Viering, Daan H H M, Weedon, Michael N, Wilson, Patricia, Guay-Woodford, Lisa, Kleta, Robert, Hussain, Khalid, Ellard, Sian, Bockenhauer, Detlef
Published in Journal of the American Society of Nephrology (01.08.2017)
Published in Journal of the American Society of Nephrology (01.08.2017)
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Wildtype heterogeneity contributes to clonal variability in genome edited cells
Westermann, Lukas, Li, Yong, Göcmen, Burulca, Niedermoser, Matthias, Rhein, Kilian, Jahn, Johannes, Cascante, Isabel, Schöler, Felix, Moser, Niklas, Neubauer, Björn, Hofherr, Alexis, Behrens, Yvonne Lisa, Göhring, Gudrun, Köttgen, Anna, Köttgen, Michael, Busch, Tilman
Published in Scientific reports (28.10.2022)
Published in Scientific reports (28.10.2022)
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Journal Article
The TRPP subfamily and polycystin-1 proteins
Semmo, Mariam, Köttgen, Michael, Hofherr, Alexis
Published in Handbook of experimental pharmacology (2014)
Published in Handbook of experimental pharmacology (2014)
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