Proarrhythmia liability assessment and the comprehensive in vitro Proarrhythmia Assay (CiPA): An industry survey on current practice
Authier, Simon, Pugsley, Michael K., Koerner, John E., Fermini, Bernard, Redfern, William S., Valentin, Jean-Pierre, Vargas, Hugo M., Leishman, Derek J., Correll, Krystle, Curtis, Michael J.
Published in Journal of pharmacological and toxicological methods (01.07.2017)
Published in Journal of pharmacological and toxicological methods (01.07.2017)
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A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium
Boulay, Emmanuel, Abernathy, Matthew M, Chui, Ray, Friedrichs, Gregory S, Gendron-Parra, Nicolas, Greiter-Wilke, Andrea, Guillon, Jean-Michel, Koerner, John E, Menard, Ariane, Steidl-Nichols, Jill, Pierson, Jennifer, Pugsley, Michael K, Rossman, Eric I, Strauss, David, Troncy, Eric, Valentin, Jean-Pierre, Wisialowski, Todd, Authier, Simon
Published in International journal of toxicology (01.01.2019)
Published in International journal of toxicology (01.01.2019)
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An Industry Survey With Focus on Cardiovascular Safety Pharmacology Study Design and Data Interpretation
Authier, Simon, Abernathy, Matthew M, Correll, Krystle, Chui, Ray W, Dalton, Jill, Foley, C Michael, Friedrichs, Gregory S, Koerner, John E, Kallman, Mary-Jeanne, Pannirselvam, Malar, Redfern, William S, Urmaliya, Vijay, Valentin, Jean-Pierre, Wisialowski, Todd, Zabka, Tanja S, Pugsley, Michael K
Published in International journal of toxicology (01.07.2020)
Published in International journal of toxicology (01.07.2020)
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The evaluation of endpoint variability and implications for study statistical power and sample size in conscious instrumented dogs
Chiang, Alan Y., Guth, Brian D., Pugsley, Michael K., Foley, C. Michael, Doyle, Jennifer M., Engwall, Michael J., Koerner, John E., Parish, Stanley T., Dustan Sarazan, R.
Published in Journal of pharmacological and toxicological methods (01.07.2018)
Published in Journal of pharmacological and toxicological methods (01.07.2018)
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An evaluation of the utility of LVdP/dt40, QA interval, LVdP/dtmin and Tau as indicators of drug-induced changes in contractility and lusitropy in dogs
Pugsley, Michael K., Guth, Brian, Chiang, Alan Y., Doyle, Jennifer M., Engwall, Michael, Guillon, Jean-Michel, Hoffmann, Peter K., Koerner, John E., Mittelstadt, Scott W., Pierson, Jennifer Beck, Rossman, Eric I., Sarazan, Dustan R., Parish, Stanley T.
Published in Journal of pharmacological and toxicological methods (01.05.2017)
Published in Journal of pharmacological and toxicological methods (01.05.2017)
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SK&F 95654-induced acute cardiovascular toxicity in Sprague-Dawley rats--histopathologic, electron microscopic, and immunohistochemical studies
Zhang, Jun, Herman, Eugene H, Knapton, Alan, Chadwick, Douglas P, Whitehurst, Virgil E, Koerner, John E, Papoian, Thomas, Ferrans, Victor J, Sistare, Frank D
Published in Toxicologic pathology (01.01.2002)
Published in Toxicologic pathology (01.01.2002)
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An evaluation of the utility of LVdP/dt 40 , QA interval, LVdP/dt min and Tau as indicators of drug-induced changes in contractility and lusitropy in dogs
Pugsley, Michael K, Guth, Brian, Chiang, Alan Y, Doyle, Jennifer M, Engwall, Michael, Guillon, Jean-Michel, Hoffmann, Peter K, Koerner, John E, Mittelstadt, Scott W, Pierson, Jennifer Beck, Rossman, Eric I, Sarazan, Dustan R, Parish, Stanley T
Published in Journal of pharmacological and toxicological methods (01.05.2017)
Published in Journal of pharmacological and toxicological methods (01.05.2017)
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Journal Article
The Diplomate in Safety Pharmacology (DSP) certification scheme
Authier, Simon, Curtis, Michael J., Soloviev, Maxim, Redfern, Will S., Kallman, Mary Jeanne, Hamlin, Robert L., Leishman, Derek J., Valentin, Jean-Pierre, Koerner, John E., Vargas, Hugo M., Botchway, Alfred, Correll, Krystle, Pugsley, Michael K.
Published in Journal of pharmacological and toxicological methods (01.09.2015)
Published in Journal of pharmacological and toxicological methods (01.09.2015)
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Cardiovascular data acquisition and analysis: An SPS industry survey
Authier, Simon, Abernathy, Matthew M., Correll, Krystle, Chui, Ray W., Dalton, Jill A., Foley, Michael C., Friedrichs, Gregory S., Koerner, John E., Kallman, Mary Jeanne, Pannirselvam, Malar, Redfern, William S., Urmaliya, Vijay, Valentin, Jean-Pierre, Wisialowski, Todd, Zabka, Tanja S., Pugsley, Michael K.
Published in Journal of pharmacological and toxicological methods (01.09.2020)
Published in Journal of pharmacological and toxicological methods (01.09.2020)
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Journal Article
ANTITHROMBOTIC COMPOUNDS
KOERNER, JOHN E, NIEDUZAK, THADDEUS R, LI, TUNG, CARR, ALBERT A, DAGE, RICHARD C, MILLER, FRANCIS P, DUDLEY, MARK W
Year of Publication 01.05.1999
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Year of Publication 01.05.1999
Patent
Probucol reduces myocardial dysfunction during reperfusion after short-term ischemia in rabbit heart
Dage, R C, Anderson, B A, Mao, S J, Koerner, J E
Published in Journal of cardiovascular pharmacology (01.01.1991)
Published in Journal of cardiovascular pharmacology (01.01.1991)
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1-PYPERIDINYL ALKANOYLARYSULFONAMIDE DERIVATIVES
NIEDUZAK, THADDEUS R, KOERNER, JOHN E, LI, TUNG, CARR, ALBERT A, DAGE, RICHARD C
Year of Publication 19.03.2002
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Year of Publication 19.03.2002
Patent
Coronary blood flow in physically trained rats
SPEAR, KIM L., KOERNER, JOHN E., TERJUNG, RONALD L.
Published in Cardiovascular research (01.03.1978)
Published in Cardiovascular research (01.03.1978)
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Journal Article
1-PIPERIDINYL ALKANOYLARYLSULFONAMIDE DERIVATIVES
NIEDUZAK, THADDEUS, R, KOERNER, JOHN, E, LI, TUNG, CARR, ALBERT, A, DAGE, RICHARD, C
Year of Publication 30.04.1997
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Year of Publication 30.04.1997
Patent
1-Piperidinyl-alkanoylarylsulfonamid-derivater
NIEDUZAK, THADDEUS, R, KOERNER, JOHN, E, LI, TUNG, CARR, ALBERT, A, DAGE, RICHARD, C
Year of Publication 25.11.1996
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Year of Publication 25.11.1996
Patent