Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination
Koeken, Valerie A. C. M, Qi, Cancan, Mourits, Vera P, de Bree, L. Charlotte J, Moorlag, Simone J. C. F. M, Sonawane, Vidhisha, Lemmers, Heidi, Dijkstra, Helga, Joosten, Leo A. B, van Laarhoven, Arjan, Xu, Cheng-Jian, van Crevel, Reinout, Netea, Mihai G, Li, Yang
Published in PLoS biology (12.09.2022)
Published in PLoS biology (12.09.2022)
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Induction of trained immunity by influenza vaccination - impact on COVID-19
Debisarun, Priya A, Gössling, Katharina L, Bulut, Ozlem, Kilic, Gizem, Zoodsma, Martijn, Liu, Zhaoli, Oldenburg, Marina, Rüchel, Nadine, Zhang, Bowen, Xu, Cheng-Jian, Struycken, Patrick, Koeken, Valerie A. C. M, Domínguez-Andrés, Jorge, Moorlag, Simone J. C. F. M, Taks, Esther, Ostermann, Philipp N, Müller, Lisa, Schaal, Heiner, Adams, Ortwin, Borkhardt, Arndt, ten Oever, Jaap, van Crevel, Reinout, Li, Yang, Netea, Mihai G
Published in PLoS pathogens (25.10.2021)
Published in PLoS pathogens (25.10.2021)
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The influence of the gut microbiome on BCG-induced trained immunity
Stražar, Martin, Mourits, Vera P, Koeken, Valerie A C M, de Bree, L Charlotte J, Moorlag, Simone J C F M, Joosten, Leo A B, van Crevel, Reinout, Vlamakis, Hera, Netea, Mihai G, Xavier, Ramnik J
Published in Genome Biology (22.09.2021)
Published in Genome Biology (22.09.2021)
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Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease
Chu, Xiaojing, Jaeger, Martin, Beumer, Joep, Bakker, Olivier B, Aguirre-Gamboa, Raul, Oosting, Marije, Smeekens, Sanne P, Moorlag, Simone, Mourits, Vera P, Koeken, Valerie A C M, de Bree, Charlotte, Jansen, Trees, Mathews, Ian T, Dao, Khoi, Najhawan, Mahan, Watrous, Jeramie D, Joosten, Irma, Sharma, Sonia, Koenen, Hans J P M, Withoff, Sebo, Jonkers, Iris H, Netea-Maier, Romana T, Xavier, Ramnik J, Franke, Lude, Xu, Cheng-Jian, Joosten, Leo A B, Sanna, Serena, Jain, Mohit, Kumar, Vinod, Clevers, Hans, Wijmenga, Cisca, Netea, Mihai G, Li, Yang
Published in Genome Biology (06.07.2021)
Published in Genome Biology (06.07.2021)
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BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination
van Meijgaarden, Krista E., Li, Wenchao, Moorlag, Simone J. C. F. M., Koeken, Valerie A. C. M., Koenen, Hans J. P. M., Joosten, Leo A. B., Vyakarnam, Annapurna, Ahmed, Asma, Rakshit, Srabanti, Adiga, Vasista, Ottenhoff, Tom H. M., Li, Yang, Netea, Mihai G., Joosten, Simone A.
Published in Nature communications (02.01.2024)
Published in Nature communications (02.01.2024)
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BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations
Wang, Yue, van Crevel, Reinout, Netea, Mihai G., Lemmers, Heidi, Dijkstra, Helga, Xu, Xiaoli, Chu, Wern Cui, Moorlag, Simone J. C. F. M., de Bree, L. Charlotte J., Koeken, Valerie A. C. M., Mourits, Vera P., Joosten, Leo A. B.
Published in Journal of Immunology Research (2020)
Published in Journal of Immunology Research (2020)
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Glutathione Metabolism Contributes to the Induction of Trained Immunity
Ferreira, Anaisa V, Koeken, Valerie A C M, Matzaraki, Vasiliki, Kostidis, Sarantos, Alarcon-Barrera, Juan Carlos, de Bree, L Charlotte J, Moorlag, Simone J C F M, Mourits, Vera P, Novakovic, Boris, Giera, Martin A, Netea, Mihai G, Domínguez-Andrés, Jorge
Published in Cells (Basel, Switzerland) (21.04.2021)
Published in Cells (Basel, Switzerland) (21.04.2021)
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BCG‐induced protection against Mycobacterium tuberculosis infection: Evidence, mechanisms, and implications for next‐generation vaccines
Foster, Mitchell, Hill, Philip C., Setiabudiawan, Todia Pediatama, Koeken, Valerie A. C. M., Alisjahbana, Bachti, Crevel, Reinout
Published in Immunological reviews (01.05.2021)
Published in Immunological reviews (01.05.2021)
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Early Clearance of Mycobacterium tuberculosis Is Associated With Increased Innate Immune Responses
Verrall, Ayesha J, Schneider, Marion, Alisjahbana, Bachti, Apriani, Lika, van Laarhoven, Arjan, Koeken, Valerie A C M, van Dorp, Suszanne, Diadani, Emira, Utama, Fitri, Hannaway, Rachel F, Indrati, Agnes, Netea, Mihai G, Sharples, Katrina, Hill, Philip C, Ussher, James E, van Crevel, Reinout
Published in The Journal of infectious diseases (28.03.2020)
Published in The Journal of infectious diseases (28.03.2020)
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Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects
Lachmandas, Ekta, Eckold, Clare, Böhme, Julia, Koeken, Valerie A C M, Marzuki, Mardiana Binte, Blok, Bastiaan, Arts, Rob J W, Chen, Jinmiao, Teng, Karen W W, Ratter, Jacqueline, Smolders, Elise J, Van den Heuvel, Corina, Stienstra, Rinke, Dockrell, Hazel M, Newell, Evan, Netea, Mihai G, Singhal, Amit, Cliff, Jacqueline M, Van Crevel, Reinout
Published in The Journal of infectious diseases (05.06.2019)
Published in The Journal of infectious diseases (05.06.2019)
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Multi-Omics Approaches in Immunological Research
Chu, Xiaojing, Zhang, Bowen, Koeken, Valerie A. C. M., Gupta, Manoj Kumar, Li, Yang
Published in Frontiers in immunology (11.06.2021)
Published in Frontiers in immunology (11.06.2021)
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Dysregulated Innate and Adaptive Immune Responses Discriminate Disease Severity in COVID-19
Janssen, Nico A F, Grondman, Inge, de Nooijer, Aline H, Boahen, Collins K, Koeken, Valerie A C M, Matzaraki, Vasiliki, Kumar, Vinod, He, Xuehui, Kox, Matthijs, Koenen, Hans J P M, Smeets, Ruben L, Joosten, Irma, Brüggemann, Roger J M, Kouijzer, Ilse J E, van der Hoeven, Hans G, Schouten, Jeroen A, Frenzel, Tim, Reijers, Monique H E, Hoefsloot, Wouter, Dofferhoff, Anton S M, van Apeldoorn, Marjan J, Blaauw, Marc J T, Veerman, Karin, Maas, Coen, Schoneveld, Arjan H, Hoefer, Imo E, Derde, Lennie P G, van Deuren, Marcel, van der Meer, Jos W M, van Crevel, Reinout, Giamarellos-Bourboulis, Evangelos J, Joosten, Leo A B, van den Heuvel, Michel M, Hoogerwerf, Jacobien, de Mast, Quirijn, Pickkers, Peter, Netea, Mihai G, van de Veerdonk, Frank L
Published in The Journal of infectious diseases (23.04.2021)
Published in The Journal of infectious diseases (23.04.2021)
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Role of Glutamine Metabolism in Host Defense Against Mycobacterium tuberculosis Infection
Koeken, Valerie A C M, Lachmandas, Ekta, Riza, Anca, Matzaraki, Vasiliki, Li, Yang, Kumar, Vinod, Oosting, Marije, Joosten, Leo A B, Netea, Mihai G, van Crevel, Reinout
Published in The Journal of infectious diseases (19.04.2019)
Published in The Journal of infectious diseases (19.04.2019)
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Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study
van Laarhoven, Arjan, Dian, Sofiati, Aguirre-Gamboa, Raúl, Avila-Pacheco, Julian, Ricaño-Ponce, Isis, Ruesen, Carolien, Annisa, Jessi, Koeken, Valerie A C M, Chaidir, Lidya, Li, Yang, Achmad, Tri Hanggono, Joosten, Leo A B, Notebaart, Richard A, Ruslami, Rovina, Netea, Mihai G, Verbeek, Marcel M, Alisjahbana, Bachti, Kumar, Vinod, Clish, Clary B, Ganiem, A Rizal, van Crevel, Reinout
Published in The Lancet infectious diseases (01.05.2018)
Published in The Lancet infectious diseases (01.05.2018)
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Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein
Keating, Samuel T., Groh, Laszlo, Thiem, Kathrin, Bekkering, Siroon, Li, Yang, Matzaraki, Vasiliki, van der Heijden, Charlotte D. C. C., van Puffelen, Jelmer H., Lachmandas, Ekta, Jansen, Trees, Oosting, Marije, de Bree, L. Charlotte J., Koeken, Valerie A. C. M., Moorlag, Simone J. C. F. M., Mourits, Vera P., van Diepen, Janna, Strienstra, Rinke, Novakovic, Boris, Stunnenberg, Hendrik G., van Crevel, Reinout, Joosten, Leo A. B., Netea, Mihai G., Riksen, Niels P.
Published in Journal of molecular medicine (Berlin, Germany) (01.06.2020)
Published in Journal of molecular medicine (Berlin, Germany) (01.06.2020)
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Auranofin Activity Exposes Thioredoxin Reductase as a Viable Drug Target in Mycobacterium abscessus
Ruth, Mike Marvin, van Rossum, Mara, Koeken, Valerie A C M, Pennings, Lian J, Svensson, Elin M, Ruesen, Carolien, Bowles, Edmee C, Wertheim, Heiman F L, Hoefsloot, Wouter, van Ingen, Jakko
Published in Antimicrobial agents and chemotherapy (01.09.2019)
Published in Antimicrobial agents and chemotherapy (01.09.2019)
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Thioridazine Is an Efflux Pump Inhibitor in Mycobacterium avium Complex but of Limited Clinical Relevance
Ruth, Mike Marvin, Pennings, Lian J, Koeken, Valerie A C M, Schildkraut, Jodie A, Hashemi, Aria, Wertheim, Heiman F L, Hoefsloot, Wouter, van Ingen, Jakko
Published in Antimicrobial agents and chemotherapy (23.06.2020)
Published in Antimicrobial agents and chemotherapy (23.06.2020)
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Immune cell characteristics and cytokine responses in adult HIV-negative tuberculous meningitis: an observational cohort study
van Laarhoven, Arjan, Dian, Sofiati, van Dorp, Suzanne, Purnama, Feby, Koeken, Valerie A. C. M., Diandini, Emira, Utami, Fitria, Livia, Resvi, Apriani, Lika, Ardiansyah, Edwin, ter Horst, Rob, Netea, Mihai G., Achmad, Tri Hanggono, Hill, Philip C., Ruslami, Rovina, Alisjahbana, Bachti, Ussher, James E., Indrati, Agnes, Verrall, Ayesha, Ganiem, Ahmad Rizal, van Crevel, Reinout
Published in Scientific reports (29.01.2019)
Published in Scientific reports (29.01.2019)
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Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19
Zoodsma, Martijn, de Nooijer, Aline H., Grondman, Inge, Gupta, Manoj Kumar, Bonifacius, Agnes, Koeken, Valerie A. C. M., Kooistra, Emma, Kilic, Gizem, Bulut, Ozlem, Gödecke, Nina, Janssen, Nico, Kox, Matthijs, Domínguez-Andrés, Jorge, van Gammeren, Adriaan J., Ermens, Anton A. M., van der Ven, Andre J. A. M., Pickkers, Peter, Blasczyk, Rainer, Behrens, Georg M. N., van de Veerdonk, Frank L., Joosten, Leo A. B., Xu, Cheng-Jian, Eiz-Vesper, Britta, Netea, Mihai G., Li, Yang
Published in Frontiers in immunology (03.11.2022)
Published in Frontiers in immunology (03.11.2022)
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