Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1–dependent mechanism that is up-regulated by interleukin-13
Highfill, Steven L., Rodriguez, Paulo C., Zhou, Qing, Goetz, Christine A., Koehn, Brent H., Veenstra, Rachelle, Taylor, Patricia A., Panoskaltsis-Mortari, Angela, Serody, Jonathan S., Munn, David H., Tolar, Jakub, Ochoa, Augusto C., Blazar, Bruce R.
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Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors
Sharma, Madhav D., Rodriguez, Paulo C., Koehn, Brent H., Baban, Babak, Cui, Yan, Guo, Gang, Shimoda, Michiko, Pacholczyk, Rafal, Shi, Huidong, Lee, Eun-Joon, Xu, Hongyan, Johnson, Theodore S., He, Yukai, Mergoub, Taha, Venable, Christopher, Bronte, Vincenzo, Wolchok, Jedd D., Blazar, Bruce R., Munn, David H.
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Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality
Saha, Asim, Aoyama, Kazutoshi, Taylor, Patricia A., Koehn, Brent H., Veenstra, Rachelle G., Panoskaltsis-Mortari, Angela, Munn, David H., Murphy, William J., Azuma, Miyuki, Yagita, Hideo, Fife, Brian T., Sayegh, Mohammed H., Najafian, Nader, Socie, Gerard, Ahmed, Rafi, Freeman, Gordon J., Sharpe, Arlene H., Blazar, Bruce R.
Published in Blood (24.10.2013)
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Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD
Koehn, Brent H., Saha, Asim, McDonald-Hyman, Cameron, Loschi, Michael, Thangavelu, Govindarajan, Ma, Lie, Zaiken, Michael, Dysthe, Josh, Krepps, Walker, Panthera, Jamie, Hippen, Keli, Jameson, Stephen C., Miller, Jeffrey S., Cooper, Matthew A., Farady, Christopher J., Iwawaki, Takao, Ting, Jenny P.-Y., Serody, Jonathan S., Murphy, William J., Hill, Geoffrey R., Murray, Peter J., Bronte, Vincenzo, Munn, David H., Zeiser, Robert, Blazar, Bruce R.
Published in Blood (07.11.2019)
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GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells
Koehn, Brent H., Apostolova, Petya, Haverkamp, Jessica M., Miller, Jeffrey S., McCullar, Valarie, Tolar, Jakub, Munn, David H., Murphy, William J., Brickey, Willie June, Serody, Jonathan S., Gabrilovich, Dmitry I., Bronte, Vincenzo, Murray, Peter J., Ting, Jenny P.-Y., Zeiser, Robert, Blazar, Bruce R.
Published in Blood (24.09.2015)
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Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD
Matta, Benjamin M., Reichenbach, Dawn K., Zhang, Xiaoli, Mathews, Lisa, Koehn, Brent H., Dwyer, Gaelen K., Lott, Jeremy M., Uhl, Franziska M., Pfeifer, Dietmar, Feser, Colby J., Smith, Michelle J., Liu, Quan, Zeiser, Robert, Blazar, Bruce R., Turnquist, Hēth R.
Published in Blood (21.07.2016)
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The IL-33/ST2 axis augments effector T-cell responses during acute GVHD
Reichenbach, Dawn K., Schwarze, Vincent, Matta, Benjamin M., Tkachev, Victor, Lieberknecht, Elisabeth, Liu, Quan, Koehn, Brent H., Pfeifer, Dietmar, Taylor, Patricia A., Prinz, Gabriele, Dierbach, Heide, Stickel, Natalie, Beck, Yvonne, Warncke, Max, Junt, Tobias, Schmitt-Graeff, Annette, Nakae, Susumu, Follo, Marie, Wertheimer, Tobias, Schwab, Lukas, Devlin, Jason, Watkins, Simon C., Duyster, Justus, Ferrara, James L.M., Turnquist, Heth R., Zeiser, Robert, Blazar, Bruce R.
Published in Blood (14.05.2015)
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Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality
Thangavelu, Govindarajan, Lee, Yu-Chi, Loschi, Michael, Schaechter, K Melanie, Feser, Colby J, Koehn, Brent H, Nowak, Elizabeth C, Zeiser, Robert, Serody, Jonathan S, Murphy, William J, Munn, David H, Chambon, Pierre, Noelle, Randolph J, Blazar, Bruce R
Published in The Journal of immunology (1950) (01.05.2019)
Published in The Journal of immunology (1950) (01.05.2019)
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The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease
McDonald-Hyman, Cameron, Muller, James T, Loschi, Michael, Thangavelu, Govindarajan, Saha, Asim, Kumari, Sudha, Reichenbach, Dawn K, Smith, Michelle J, Zhang, Guoan, Koehn, Brent H, Lin, Jiqiang, Mitchell, Jason S, Fife, Brian T, Panoskaltsis-Mortari, Angela, Feser, Colby J, Kirchmeier, Andrew Kemal, Osborn, Mark J, Hippen, Keli L, Kelekar, Ameeta, Serody, Jonathan S, Turka, Laurence A, Munn, David H, Chi, Hongbo, Neubert, Thomas A, Dustin, Michael L, Blazar, Bruce R
Published in The Journal of clinical investigation (01.10.2018)
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Dual JAK2/Aurora kinase A inhibition prevents human skin graft rejection by allo‐inactivation and ILC2‐mediated tissue repair
Walton, Kelly, Walker, Kirsti, Riddle, Megan, Koehn, Brent H., Reff, Jordan, Sagatys, Elizabeth M., Linden, Michael A., Pidala, Joseph, Kim, Jongphil, Lee, Marie C., Kiluk, John V., Hui, Jane Yuet Ching, Yun, Sang Y., Xing, Yan, Stefanski, Heather, Lawrence, Harshani R., Lawrence, Nicholas J., Tolar, Jakub, Anasetti, Claudio, Blazar, Bruce R., Sebti, Said M., Betts, Brian C.
Published in American journal of transplantation (01.03.2022)
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Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses
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Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help
Monjazeb, Arta M, Tietze, Julia K, Grossenbacher, Steven K, Hsiao, Hui-Hua, Zamora, Anthony E, Mirsoian, Annie, Koehn, Brent, Blazar, Bruce R, Weiss, Jonathan M, Wiltrout, Robert H, Sckisel, Gail D, Murphy, William J
Published in PloS one (13.08.2014)
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PD-1-Dependent Mechanisms Maintain Peripheral Tolerance of Donor-Reactive CD8+ T Cells to Transplanted Tissue
Koehn, Brent H, Ford, Mandy L, Ferrer, Ivana R, Borom, Keshawna, Gangappa, Shivaprakash, Kirk, Allan D, Larsen, Christian P
Published in The Journal of immunology (1950) (15.10.2008)
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Limiting the amount and duration of antigen exposure during priming increases memory T cell requirement for costimulation during recall
Floyd, Tamara L, Koehn, Brent H, Kitchens, William H, Robertson, Jennifer M, Cheeseman, Jennifer A, Stempora, Linda, Larsen, Christian P, Ford, Mandy L
Published in The Journal of immunology (1950) (15.02.2011)
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Fully MHC-Disparate Mixed Hemopoietic Chimeras Show Specific Defects in the Control of Chronic Viral Infections
Koehn, Brent H, Williams, Matthew A, Borom, Keshawna, Gangappa, Shivaprakash, Pearson, Thomas C, Ahmed, Rafi, Larsen, Christian P
Published in Journal of Immunology (15.08.2007)
Published in Journal of Immunology (15.08.2007)
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