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Published in The Journal of pharmacology and experimental therapeutics (01.01.1994)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.1994)
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Pharmacology of N-[4-(4-morpholinylcarbonyl)benzoyl]-L-valyl-N- [3,3,4,4,4-pentafluoro-1-(1-methylethyl)-2-oxobutyl]-L-prolinamide (MDL 101,146): a potent orally active inhibitor of human neutrophil elastase
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1994)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1994)
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Inhibition of Human Neutrophil Elastase. 4. Design, Synthesis, X-ray Crystallographic Analysis, and Structure−Activity Relationships for a Series of P2-Modified, Orally Active Peptidyl Pentafluoroethyl Ketones
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Published in Journal of medicinal chemistry (02.07.1998)
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Application of a conformationally restricted Phe-Leu dipeptide mimetic to the design of a combined inhibitor of angiotensin I-converting enzyme and neutral endopeptidase 24.11
Flynn, Gary A, Beight, Douglas W, Mehdi, Shujaath, Koehl, Jack R, Giroux, Eugene L, French, John F, Hake, Paul W, Dage, Richard C
Published in Journal of medicinal chemistry (06.08.1993)
Published in Journal of medicinal chemistry (06.08.1993)
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The synthesis of ketomethylene pseudopeptide analogues of dipeptide aldehyde inhibitors of calpain
Angelastro, Michael R., Marquart, Angela L., Mehdi, Shujaath, Koehl, Jack R., Vaz, Roy J., Bey, Philippe, Peet, Norton P.
Published in Bioorganic & medicinal chemistry letters (18.01.1999)
Published in Bioorganic & medicinal chemistry letters (18.01.1999)
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Preparation of α-keto ester enol acetates as potential prodrugs of human neutrophil elastase inhibitors
Burkhart, Joseph P., Mehdi, Shujaath, Koehl, Jack R., Angelastro, Michael R., Bey, Philippe, Peet, Norton P.
Published in Bioorganic & medicinal chemistry letters (06.01.1998)
Published in Bioorganic & medicinal chemistry letters (06.01.1998)
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The inhibition of human neutrophil elastase and cathepsin G by peptidyl 1,2-dicarbonyl derivatives
Mehdi, Shujaath, Angelastro, Michael P., Burkhart, Joseph P., Koehl, Jack R., Peet, Norton P., Bey, Philippe
Published in Biochemical and biophysical research communications (30.01.1990)
Published in Biochemical and biophysical research communications (30.01.1990)
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Alcohol as a nutrient: interactions between ethanol and carbohydrate
Guthrie, G D, Myers, K J, Gesser, E J, White, G W, Koehl, J R
Published in Alcoholism, clinical and experimental research (01.02.1990)
Published in Alcoholism, clinical and experimental research (01.02.1990)
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Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats
Markgraf, C G, Velayo, N L, Johnson, M P, McCarty, D R, Medhi, S, Koehl, J R, Chmielewski, P A, Linnik, M D
Published in Stroke (1970) (01.01.1998)
Published in Stroke (1970) (01.01.1998)
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Inhibition of Human Neutrophil Elastase with Peptidyl Electrophilic Ketones. 2. Orally Active PG-Val-Pro-Val Pentafluoroethyl Ketones
Angelastro, Michael R, Baugh, Larry E, Bey, Philippe, Burkhart, Joseph P, Chen, Teng-Man, Durham, Sherrie L, Hare, C. Michelle, Huber, Edward W, Janusz, Michael J
Published in Journal of medicinal chemistry (01.12.1994)
Published in Journal of medicinal chemistry (01.12.1994)
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Hydroxyoxazolidines as α-aminoacetaldehyde equivalents: Novel inhibitors of calpain
Peet, Norton P., Kim, Hwa-Ok, Marquart, Angela L., Angelastro, Michael R., Nieduzak, Thaddeus R., White, Julie N., Friedrich, Dirk, Flynn, Gary A., Webster, Mark E., Vaz, Roy J., Linnik, Matthew D., Koehl, Jack R., Mehdi, Shujaath, Bey, Philippe, Emary, Bart, Hwang, Kin-Kai
Published in Bioorganic & medicinal chemistry letters (16.08.1999)
Published in Bioorganic & medicinal chemistry letters (16.08.1999)
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Hydroxyoxazolidines as alpha-aminoacetaldehye equivalents: novel inhibitors of calpain
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Published in Bioorganic & medicinal chemistry letters (16.08.1999)
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Published in Bioorganic & medicinal chemistry letters (16.08.1999)
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