Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
Pein, Helmut, Ville, Alexia, Pace, Simona, Temml, Veronika, Garscha, Ulrike, Raasch, Martin, Alsabil, Khaled, Viault, Guillaume, Dinh, Chau-Phi, Guilet, David, Troisi, Fabiana, Neukirch, Konstantin, König, Stefanie, Bilancia, Rosella, Waltenberger, Birgit, Stuppner, Hermann, Wallert, Maria, Lorkowski, Stefan, Weinigel, Christina, Rummler, Silke, Birringer, Marc, Roviezzo, Fiorentina, Sautebin, Lidia, Helesbeux, Jean-Jacques, Séraphin, Denis, Mosig, Alexander S., Schuster, Daniela, Rossi, Antonietta, Richomme, Pascal, Werz, Oliver, Koeberle, Andreas
Published in Nature communications (20.09.2018)
Published in Nature communications (20.09.2018)
Get full text
Journal Article
Revealing the macromolecular targets of complex natural products
Reker, Daniel, Perna, Anna M., Rodrigues, Tiago, Schneider, Petra, Reutlinger, Michael, Mönch, Bettina, Koeberle, Andreas, Lamers, Christina, Gabler, Matthias, Steinmetz, Heinrich, Müller, Rolf, Schubert-Zsilavecz, Manfred, Werz, Oliver, Schneider, Gisbert
Published in Nature chemistry (01.12.2014)
Published in Nature chemistry (01.12.2014)
Get full text
Journal Article
Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans
Sharifi, Samim, Chaudhari, Prerana, Martirosyan, Asya, Eberhardt, Alexander Otto, Witt, Finja, Gollowitzer, André, Lange, Lisa, Woitzat, Yvonne, Okoli, Eberechukwu Maryann, Li, Huahui, Rahnis, Norman, Kirkpatrick, Joanna, Werz, Oliver, Ori, Alessandro, Koeberle, Andreas, Bierhoff, Holger, Ermolaeva, Maria
Published in Nature communications (24.02.2024)
Published in Nature communications (24.02.2024)
Get full text
Journal Article
Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms
Koeberle, Solveigh C., Gollowitzer, André, Laoukili, Jamila, Kranenburg, Onno, Werz, Oliver, Koeberle, Andreas, Kipp, Anna P.
Published in Redox biology (01.01.2020)
Published in Redox biology (01.01.2020)
Get full text
Journal Article
Acetyl-CoA carboxylase 1 regulates endothelial cell migration by shifting the phospholipid composition
Glatzel, Daniel K., Koeberle, Andreas, Pein, Helmut, Löser, Konstantin, Stark, Anna, Keksel, Nelli, Werz, Oliver, Müller, Rolf, Bischoff, Iris, Fürst, Robert
Published in Journal of lipid research (01.02.2018)
Published in Journal of lipid research (01.02.2018)
Get full text
Journal Article
PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling
Thürmer, Maria, Gollowitzer, André, Pein, Helmut, Neukirch, Konstantin, Gelmez, Elif, Waltl, Lorenz, Wielsch, Natalie, Winkler, René, Löser, Konstantin, Grander, Julia, Hotze, Madlen, Harder, Sönke, Döding, Annika, Meßner, Martina, Troisi, Fabiana, Ardelt, Maximilian, Schlüter, Hartmut, Pachmayr, Johanna, Gutiérrez-Gutiérrez, Óscar, Rudolph, Karl Lenhard, Thedieck, Kathrin, Schulze-Späte, Ulrike, González-Estévez, Cristina, Kosan, Christian, Svatoš, Aleš, Kwiatkowski, Marcel, Koeberle, Andreas
Published in Nature communications (27.05.2022)
Published in Nature communications (27.05.2022)
Get full text
Journal Article
α-Tocopherol-13'-Carboxychromanol Induces Cell Cycle Arrest and Cell Death by Inhibiting the SREBP1-SCD1 Axis and Causing Imbalance in Lipid Desaturation
Liao, Sijia, Gollowitzer, André, Börmel, Lisa, Maier, Charlotte, Gottschalk, Luisa, Werz, Oliver, Wallert, Maria, Koeberle, Andreas, Lorkowski, Stefan
Published in International journal of molecular sciences (25.05.2023)
Published in International journal of molecular sciences (25.05.2023)
Get full text
Journal Article
Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding
Koeberle, Andreas, Shindou, Hideo, Koeberle, Solveigh C., Laufer, Stefan A., Shimizu, Takao, Werz, Oliver
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2013)
Get full text
Journal Article
Olive Oil Extracts and Oleic Acid Attenuate the LPS-Induced Inflammatory Response in Murine RAW264.7 Macrophages but Induce the Release of Prostaglandin E2
Müller, Anke Katharina, Albrecht, Franziska, Rohrer, Carsten, Koeberle, Andreas, Werz, Oliver, Schlörmann, Wiebke, Glei, Michael, Lorkowski, Stefan, Wallert, Maria
Published in Nutrients (11.12.2021)
Published in Nutrients (11.12.2021)
Get full text
Journal Article
A vitamin E long-chain metabolite and the inspired drug candidate α-amplexichromanol relieve asthma features in an experimental model of allergen sensitization
Cerqua, Ida, Neukirch, Konstantin, Terlizzi, Michela, Granato, Elisabetta, Caiazzo, Elisabetta, Cicala, Carla, Ialenti, Armando, Capasso, Raffaele, Werz, Oliver, Sorrentino, Rosalinda, Seraphin, Denis, Helesbeux, Jean-Jacques, Cirino, Giuseppe, Koeberle, Andreas, Roviezzo, Fiorentina, Rossi, Antonietta
Published in Pharmacological research (01.07.2022)
Published in Pharmacological research (01.07.2022)
Get full text
Journal Article
Diversity of Chromanol and Chromenol Structures and Functions: An Emerging Class of Anti-Inflammatory and Anti-Carcinogenic Agents
Wallert, Maria, Kluge, Stefan, Schubert, Martin, Koeberle, Andreas, Werz, Oliver, Birringer, Marc, Lorkowski, Stefan
Published in Frontiers in pharmacology (21.04.2020)
Published in Frontiers in pharmacology (21.04.2020)
Get full text
Journal Article
SAR Studies on Curcumin’s Pro-inflammatory Targets: Discovery of Prenylated Pyrazolocurcuminoids as Potent and Selective Novel Inhibitors of 5‑Lipoxygenase
Koeberle, Andreas, Muñoz, Eduardo, Appendino, Giovanni B, Minassi, Alberto, Pace, Simona, Rossi, Antonietta, Weinigel, Christina, Barz, Dagmar, Sautebin, Lidia, Caprioglio, Diego, Collado, Juan A, Werz, Oliver
Published in Journal of medicinal chemistry (10.07.2014)
Published in Journal of medicinal chemistry (10.07.2014)
Get full text
Journal Article
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
Koeberle, Solveigh C, Romir, Johannes, Fischer, Stefan, Koeberle, Andreas, Schattel, Verena, Albrecht, Wolfgang, Grütter, Christian, Werz, Oliver, Rauh, Daniel, Stehle, Thilo, Laufer, Stefan A
Published in Nature chemical biology (25.12.2011)
Published in Nature chemical biology (25.12.2011)
Get full text
Journal Article
The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages
Wolfram, Theresa, Weidenbach, Leonie M, Adolf, Johanna, Schwarz, Maria, Schädel, Patrick, Gollowitzer, André, Werz, Oliver, Koeberle, Andreas, Kipp, Anna P, Koeberle, Solveigh C
Published in International journal of molecular sciences (14.10.2021)
Published in International journal of molecular sciences (14.10.2021)
Get full text
Journal Article
Licofelone Suppresses Prostaglandin E2 Formation by Interference with the Inducible Microsomal Prostaglandin E2 Synthase-1
Koeberle, Andreas, Siemoneit, Ulf, Bühring, Ulrike, Northoff, Hinnak, Laufer, Stefan, Albrecht, Wolfgang, Werz, Oliver
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)
Get full text
Journal Article
The Bibenzyl Canniprene Inhibits the Production of Pro-Inflammatory Eicosanoids and Selectively Accumulates in Some Cannabis sativa Strains
Allegrone, Gianna, Pollastro, Federica, Magagnini, Gianmaria, Taglialatela-Scafati, Orazio, Seegers, Julia, Koeberle, Andreas, Werz, Oliver, Appendino, Giovanni
Published in Journal of natural products (Washington, D.C.) (24.03.2017)
Published in Journal of natural products (Washington, D.C.) (24.03.2017)
Get full text
Journal Article