Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis
Koczor, Christopher A., Saville, Kate M., Andrews, Joel F., Clark, Jennifer, Fang, Qingming, Li, Jianfeng, Al-Rahahleh, Rasha Q., Ibrahim, Md, McClellan, Steven, Makarov, Mikhail V., Migaud, Marie E., Sobol, Robert W.
Published in Cell reports (Cambridge) (02.11.2021)
Published in Cell reports (Cambridge) (02.11.2021)
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Journal Article
Detection of differentially methylated gene promoters in failing and nonfailing human left ventricle myocardium using computation analysis
Koczor, Christopher A, Lee, Eva K, Torres, Rebecca A, Boyd, Amy, Vega, J David, Uppal, Karan, Yuan, Fan, Fields, Earl J, Samarel, Allen M, Lewis, William
Published in Physiological genomics (15.07.2013)
Published in Physiological genomics (15.07.2013)
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Journal Article
Mitochondrial DNA Damage Initiates a Cell Cycle Arrest by a Chk2-associated Mechanism in Mammalian Cells
Koczor, Christopher A., Shokolenko, Inna N., Boyd, Amy K., Balk, Shawn P., Wilson, Glenn L., LeDoux, Susan P.
Published in The Journal of biological chemistry (25.12.2009)
Published in The Journal of biological chemistry (25.12.2009)
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Journal Article
Hydrogen sulfide regulates cardiac mitochondrial biogenesis via the activation of AMPK
Shimizu, Yuuki, Polavarapu, Rohini, Eskla, Kattri-Liis, Nicholson, Chad K., Koczor, Christopher A., Wang, Rui, Lewis, William, Shiva, Sruti, Lefer, David J., Calvert, John W.
Published in Journal of molecular and cellular cardiology (01.03.2018)
Published in Journal of molecular and cellular cardiology (01.03.2018)
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Journal Article
Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress
Fang, Qingming, Andrews, Joel, Sharma, Nidhi, Wilk, Anna, Clark, Jennifer, Slyskova, Jana, Koczor, Christopher A, Lans, Hannes, Prakash, Aishwarya, Sobol, Robert W
Published in Nucleic acids research (09.07.2019)
Published in Nucleic acids research (09.07.2019)
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Journal Article
Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility
Koczor, Christopher A., Thompson, Marlo K., Sharma, Nidhi, Prakash, Aishwarya, Sobol, Robert W.
Published in DNA repair (01.03.2023)
Published in DNA repair (01.03.2023)
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Journal Article
NAD+-mediated regulation of mammalian base excision repair
Saville, Kate M., Clark, Jennifer, Wilk, Anna, Rogers, Gresyn D., Andrews, Joel F., Koczor, Christopher A., Sobol, Robert W.
Published in DNA repair (01.09.2020)
Published in DNA repair (01.09.2020)
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Journal Article
Nucleoside reverse transcriptase inhibitor toxicity and mitochondrial DNA
Koczor, Christopher A, Lewis, William
Published in Expert opinion on drug metabolism & toxicology (01.12.2010)
Published in Expert opinion on drug metabolism & toxicology (01.12.2010)
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Journal Article
AZT-induced mitochondrial toxicity: an epigenetic paradigm for dysregulation of gene expression through mitochondrial oxidative stress
Koczor, Christopher A, Jiao, Zhe, Fields, Earl, Russ, Rodney, Ludaway, Tomika, Lewis, William
Published in Physiological genomics (01.10.2015)
Published in Physiological genomics (01.10.2015)
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Journal Article
Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage
Koczor, Christopher A, Saville, Kate M, Al-Rahahleh, Rasha Q, Andrews, Joel F, Li, Jianfeng, Sobol, Robert W
Published in Methods in molecular biology (Clifton, N.J.) (2023)
Published in Methods in molecular biology (Clifton, N.J.) (2023)
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Journal Article
Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity
Saville, Kate M., Al-Rahahleh, Rasha Q., Siddiqui, Aisha H., Andrews, Morgan E., Roos, Wynand P., Koczor, Christopher A., Andrews, Joel F., Hayat, Faisal, Migaud, Marie E., Sobol, Robert W.
Published in DNA repair (01.08.2024)
Published in DNA repair (01.08.2024)
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Journal Article
Targeting repair proteins to the mitochondria of mammalian cells through stable transfection, transient transfection, viral transduction, and TAT-mediated protein transduction
Koczor, Christopher A, Snyder, Janet W, Shokolenko, Inna N, Dobson, Allison W, Wilson, Glenn L, Ledoux, Susan P
Published in Methods in molecular biology (Clifton, N.J.) (2009)
Published in Methods in molecular biology (Clifton, N.J.) (2009)
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Journal Article
Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD + Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase
Li, Jianfeng, Koczor, Christopher A, Saville, Kate M, Hayat, Faisal, Beiser, Alison, McClellan, Steven, Migaud, Marie E, Sobol, Robert W
Published in Cancers (22.07.2022)
Published in Cancers (22.07.2022)
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Journal Article
Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens
Koczor, Christopher A, Haider, Aaron J, Saville, Kate M, Li, Jianfeng, Andrews, Joel F, Beiser, Alison V, Sobol, Robert W
Published in Cancers (28.07.2022)
Published in Cancers (28.07.2022)
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Journal Article
Ecstasy (MDMA) Alters Cardiac Gene Expression and DNA Methylation: Implications for Circadian Rhythm Dysfunction in the Heart
Koczor, Christopher A, Ludlow, Ivan, Hight, 2nd, Robert S, Jiao, Zhe, Fields, Earl, Ludaway, Tomika, Russ, Rodney, Torres, Rebecca A, Lewis, William
Published in Toxicological sciences (01.11.2015)
Published in Toxicological sciences (01.11.2015)
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Journal Article
A multi-scale map of protein assemblies in the DNA damage response
Kratz, Anton, Kim, Minkyu, Kelly, Marcus R., Zheng, Fan, Koczor, Christopher A., Li, Jianfeng, Ono, Keiichiro, Qin, Yue, Churas, Christopher, Chen, Jing, Pillich, Rudolf T., Park, Jisoo, Modak, Maya, Collier, Rachel, Licon, Kate, Pratt, Dexter, Sobol, Robert W., Krogan, Nevan J., Ideker, Trey
Published in Cell systems (21.06.2023)
Published in Cell systems (21.06.2023)
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Journal Article
Connective tissue growth factor regulates cardiac function and tissue remodeling in a mouse model of dilated cardiomyopathy
Koshman, Yevgeniya E, Sternlicht, Mark D, Kim, Taehoon, O'Hara, Christopher P, Koczor, Christopher A, Lewis, William, Seeley, Todd W, Lipson, Kenneth E, Samarel, Allen M
Published in Journal of molecular and cellular cardiology (01.12.2015)
Published in Journal of molecular and cellular cardiology (01.12.2015)
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Journal Article
Methamphetamine and HIV-Tat alter murine cardiac DNA methylation and gene expression
Koczor, Christopher A., Fields, Earl, Jedrzejczak, Mark J., Jiao, Zhe, Ludaway, Tomika, Russ, Rodney, Shang, Joan, Torres, Rebecca A., Lewis, William
Published in Toxicology and applied pharmacology (01.11.2015)
Published in Toxicology and applied pharmacology (01.11.2015)
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Journal Article