Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants
Weigang, Sebastian, Fuchs, Jonas, Zimmer, Gert, Schnepf, Daniel, Kern, Lisa, Beer, Julius, Luxenburger, Hendrik, Ankerhold, Jakob, Falcone, Valeria, Kemming, Janine, Hofmann, Maike, Thimme, Robert, Neumann-Haefelin, Christoph, Ulferts, Svenja, Grosse, Robert, Hornuss, Daniel, Tanriver, Yakup, Rieg, Siegbert, Wagner, Dirk, Huzly, Daniela, Schwemmle, Martin, Panning, Marcus, Kochs, Georg
Published in Nature communications (04.11.2021)
Published in Nature communications (04.11.2021)
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Journal Article
Characterization of pre-existing and induced SARS-CoV-2-specific CD8 + T cells
Schulien, Isabel, Kemming, Janine, Oberhardt, Valerie, Wild, Katharina, Seidel, Lea M, Killmer, Saskia, Sagar, Daul, Franziska, Salvat Lago, Marilyn, Decker, Annegrit, Luxenburger, Hendrik, Binder, Benedikt, Bettinger, Dominik, Sogukpinar, Oezlem, Rieg, Siegbert, Panning, Marcus, Huzly, Daniela, Schwemmle, Martin, Kochs, Georg, Waller, Cornelius F, Nieters, Alexandra, Duerschmied, Daniel, Emmerich, Florian, Mei, Henrik E, Schulz, Axel Ronald, Llewellyn-Lacey, Sian, Price, David A, Boettler, Tobias, Bengsch, Bertram, Thimme, Robert, Hofmann, Maike, Neumann-Haefelin, Christoph
Published in Nature medicine (01.01.2021)
Published in Nature medicine (01.01.2021)
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Journal Article
Tick-transmitted thogotovirus gains high virulence by a single MxA escape mutation in the viral nucleoprotein
Fuchs, Jonas, Oschwald, Alexander, Graf, Laura, Kochs, Georg
Published in PLoS pathogens (16.11.2020)
Published in PLoS pathogens (16.11.2020)
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Journal Article
Essential Role of Interferon Response in Containing Human Pathogenic Bourbon Virus
Fuchs, Jonas, Straub, Tobias, Seidl, Maximilian, Kochs, Georg
Published in Emerging infectious diseases (01.07.2019)
Published in Emerging infectious diseases (01.07.2019)
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Journal Article
The Viral Nucleoprotein Determines Mx Sensitivity of Influenza A Viruses
Zimmermann, Petra, Mänz, Benjamin, Haller, Otto, Schwemmle, Martin, Kochs, Georg
Published in Journal of Virology (01.08.2011)
Published in Journal of Virology (01.08.2011)
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Journal Article
COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation
Reinscheid, Matthias, Luxenburger, Hendrik, Karl, Vivien, Graeser, Anne, Giese, Sebastian, Ciminski, Kevin, Reeg, David B, Oberhardt, Valerie, Roehlen, Natascha, Lang-Meli, Julia, Heim, Kathrin, Gross, Nina, Baum, Christina, Rieg, Siegbert, Speer, Claudius, Emmerich, Florian, Breisinger, Susanne, Steinmann, Daniel, Bengsch, Bertram, Boettler, Tobias, Kochs, Georg, Schwemmle, Martin, Thimme, Robert, Neumann-Haefelin, Christoph, Hofmann, Maike
Published in Nature communications (08.08.2022)
Published in Nature communications (08.08.2022)
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Journal Article
In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein
Deeg, Christoph M, Hassan, Ebrahim, Mutz, Pascal, Rheinemann, Lara, Götz, Veronika, Magar, Linda, Schilling, Mirjam, Kallfass, Carsten, Nürnberger, Cindy, Soubies, Sébastien, Kochs, Georg, Haller, Otto, Schwemmle, Martin, Staeheli, Peter
Published in The Journal of experimental medicine (01.05.2017)
Published in The Journal of experimental medicine (01.05.2017)
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Journal Article
Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections
Mordstein, Markus, Neugebauer, Eva, Ditt, Vanessa, Jessen, Birthe, Rieger, Toni, Falcone, Valeria, Sorgeloos, Frederic, Ehl, Stephan, Mayer, Daniel, Kochs, Georg, Schwemmle, Martin, Günther, Stephan, Drosten, Christian, Michiels, Thomas, Staeheli, Peter
Published in Journal of Virology (01.06.2010)
Published in Journal of Virology (01.06.2010)
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Journal Article
Human MxB Protein Is a Pan-herpesvirus Restriction Factor
Schilling, Mirjam, Bulli, Lorenzo, Weigang, Sebastian, Graf, Laura, Naumann, Sebastian, Patzina, Corinna, Wagner, Valentina, Bauersfeld, Liane, Goujon, Caroline, Hengel, Hartmut, Halenius, Anne, Ruzsics, Zsolt, Schaller, Torsten, Kochs, Georg
Published in Journal of virology (01.09.2018)
Published in Journal of virology (01.09.2018)
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Journal Article
Structural basis of oligomerization in the stalk region of dynamin-like MxA
Behlke, Joachim, Daumke, Oliver, Paeschke, Susann, Kochs, Georg, Gao, Song, Haller, Otto, von der Malsburg, Alexander
Published in Nature (London) (27.05.2010)
Published in Nature (London) (27.05.2010)
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Journal Article
Multiple Anti-Interferon Actions of the Influenza A Virus NS1 Protein
Georg Kochs, Adolfo García-Sastre, Luis Martínez-Sobrido
Published in Journal of Virology (01.07.2007)
Published in Journal of Virology (01.07.2007)
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Journal Article
Impaired immune response drives age-dependent severity of COVID-19
Beer, Julius, Crotta, Stefania, Breithaupt, Angele, Ohnemus, Annette, Becker, Jan, Sachs, Benedikt, Kern, Lisa, Llorian, Miriam, Ebert, Nadine, Labroussaa, Fabien, Nhu Thao, Tran Thi, Trueeb, Bettina Salome, Jores, Joerg, Thiel, Volker, Beer, Martin, Fuchs, Jonas, Kochs, Georg, Wack, Andreas, Schwemmle, Martin, Schnepf, Daniel
Published in The Journal of experimental medicine (05.12.2022)
Published in The Journal of experimental medicine (05.12.2022)
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Journal Article
Macrophages and Dendritic Cells Are Not the Major Source of Pro-Inflammatory Cytokines Upon SARS-CoV-2 Infection
Niles, Marc A., Gogesch, Patricia, Kronhart, Stefanie, Ortega Iannazzo, Samira, Kochs, Georg, Waibler, Zoe, Anzaghe, Martina
Published in Frontiers in immunology (26.05.2021)
Published in Frontiers in immunology (26.05.2021)
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Journal Article
Structure of Myxovirus Resistance Protein A Reveals Intra- and Intermolecular Domain Interactions Required for the Antiviral Function
Gao, Song, von der Malsburg, Alexander, Dick, Alexej, Faelber, Katja, Schröder, Gunnar F., Haller, Otto, Kochs, Georg, Daumke, Oliver
Published in Immunity (Cambridge, Mass.) (28.10.2011)
Published in Immunity (Cambridge, Mass.) (28.10.2011)
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Journal Article
Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein
Mänz, Benjamin, Dornfeld, Dominik, Götz, Veronika, Zell, Roland, Zimmermann, Petra, Haller, Otto, Kochs, Georg, Schwemmle, Martin
Published in PLoS pathogens (01.03.2013)
Published in PLoS pathogens (01.03.2013)
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Journal Article
Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA
Mitchell, Patrick S., Patzina, Corinna, Emerman, Michael, Haller, Otto, Malik, Harmit S., Kochs, Georg
Published in Cell host & microbe (18.10.2012)
Published in Cell host & microbe (18.10.2012)
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Journal Article
Incoming RNA Virus Nucleocapsids Containing a 5′-Triphosphorylated Genome Activate RIG-I and Antiviral Signaling
Weber, Michaela, Gawanbacht, Ali, Habjan, Matthias, Rang, Andreas, Borner, Christoph, Schmidt, Anna Mareike, Veitinger, Sophie, Jacob, Ralf, Devignot, Stéphanie, Kochs, Georg, García-Sastre, Adolfo, Weber, Friedemann
Published in Cell host & microbe (13.03.2013)
Published in Cell host & microbe (13.03.2013)
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