Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1
Feldman, Richard I., Wu, James M., Polokoff, Mark A., Kochanny, Monica J., Dinter, Harald, Zhu, Daguang, Biroc, Sandra L., Alicke, Bruno, Bryant, Judi, Yuan, Shendong, Buckman, Brad O., Lentz, Dao, Ferrer, Mike, Whitlow, Marc, Adler, Marc, Finster, Silke, Chang, Zheng, Arnaiz, Damian O.
Published in The Journal of biological chemistry (20.05.2005)
Published in The Journal of biological chemistry (20.05.2005)
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Journal Article
Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa
Adler, Marc, Kochanny, Monica J, Ye, Bin, Rumennik, Galina, Light, David R, Biancalana, Sara, Whitlow, Marc
Published in Biochemistry (Easton) (31.12.2002)
Published in Biochemistry (Easton) (31.12.2002)
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Journal Article
Thiophene-Anthranilamides as Highly Potent and Orally Available Factor Xa Inhibitors
Ye, Bin, Arnaiz, Damian O, Chou, Yuo-Ling, Griedel, Brian D, Karanjawala, Rushad, Lee, Wheeseong, Morrissey, Michael M, Sacchi, Karna L, Sakata, Steven T, Shaw, Kenneth J, Wu, Shung C, Zhao, Zuchun, Adler, Marc, Cheeseman, Sarah, Dole, William P, Ewing, Janice, Fitch, Richard, Lentz, Dao, Liang, Amy, Light, David, Morser, John, Post, Joseph, Rumennik, Galina, Subramanyam, Babu, Sullivan, Mark E, Vergona, Ron, Walters, Janette, Wang, Yi-Xin, White, Kathy A, Whitlow, Marc, Kochanny, Monica J
Published in Journal of medicinal chemistry (28.06.2007)
Published in Journal of medicinal chemistry (28.06.2007)
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Journal Article
Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: Optimization of BX- 517
Islam, Imadul, Brown, Greg, Bryant, Judi, Hrvatin, Paul, Kochanny, Monica J., Phillips, Gary B., Yuan, Shendong, Adler, Marc, Whitlow, Marc, Lentz, Dao, Polokoff, Mark A., Wu, James, Shen, Jun, Walters, Janette, Ho, Elena, Subramanyam, Babu, Zhu, Daguang, Feldman, Richard I., Arnaiz, Damian O.
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
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Journal Article
Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: Design, synthesis and biological activity
Islam, Imadul, Bryant, Judi, Chou, Yuo-Ling, Kochanny, Monica J., Lee, Wheeseong, Phillips, Gary B., Yu, Hongyi, Adler, Marc, Whitlow, Marc, Ho, Elena, Lentz, Dao, Polokoff, Mark A., Subramanyam, Babu, Wu, James M., Zhu, Daguang, Feldman, Richard I., Arnaiz, Damian O.
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
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Journal Article
Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase
KIRKLAND, Thomas A, ADLER, Marc, THUNNISSEN, Marjolein, TRINH, Lan, WHITLOW, Marc, BIN YE, HONG YE, PARKINSON, John, GUILFORD, William J, BAUMAN, John G, MING CHEN, HAEGGSTRÖM, Jesper Z, KING, Beverly, KOCHANNY, Monica J, LIANG, Amy M, MENDOZA, Lisa, PHILLIPS, Gary B
Published in Bioorganic & medicinal chemistry (01.05.2008)
Published in Bioorganic & medicinal chemistry (01.05.2008)
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Journal Article
Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa
Kochanny, Monica J., Adler, Marc, Ewing, Janice, Griedel, Brian D., Ho, Elena, Karanjawala, Rushad, Lee, Wheeseong, Lentz, Dao, Liang, Amy M., Morrissey, Michael M., Phillips, Gary B., Post, Joseph, Sacchi, Karna L., Sakata, Steven T., Subramanyam, Babu, Vergona, Ron, Walters, Janette, White, Kathy A., Whitlow, Marc, Ye, Bin, Zhao, Zuchun, Shaw, Kenneth J.
Published in Bioorganic & medicinal chemistry (01.03.2007)
Published in Bioorganic & medicinal chemistry (01.03.2007)
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Journal Article
Structure–Activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors
Chou, Yuo-Ling, Davey, David D, Eagen, Keith A, Griedel, Brian D, Karanjawala, Rushad, Phillips, Gary B, Sacchi, Karna L, Shaw, Kenneth J, Wu, Shung C, Lentz, Dao, Liang, Amy M, Trinh, Lan, Morrissey, Michael M, Kochanny, Monica J
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
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Journal Article
Design, Synthesis, and Biological Activity of Novel Factor Xa Inhibitors: 4-Aryloxy Substituents of 2,6-Diphenoxypyridines
Ng, Howard P., Buckman, Brad O., Eagen, Keith A., Guilford, William J., Kochanny, Monica J., Mohan, Raju, Shaw, Kenneth J., Wu, Shung C., Lentz, Dao, Liang, Amy, Trinh, Lan, Ho, Elena, Smith, David, Subramanyam, Babu, Vergona, Ron, Walters, Janette, White, Kathy A., Sullivan, Mark E., Morrissey, Michael M., Phillips, Gary B.
Published in Bioorganic & medicinal chemistry (01.03.2002)
Published in Bioorganic & medicinal chemistry (01.03.2002)
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Journal Article
Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors
Boger, Dale L, Kochanny, Monica J, Cai, Hui, Wyatt, Diane, Kitos, Paul A, Warren, M.S, Ramcharan, J, Gooljarsingh, Lata T, Benkovic, Stephen J
Published in Bioorganic & medicinal chemistry (01.06.1998)
Published in Bioorganic & medicinal chemistry (01.06.1998)
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Journal Article
Fluorine-18 labeled progestin ketals: synthesis and target tissue uptake selectivity of potential imaging agents for receptor-positive breast tumors
Kochanny, Monica J, VanBrocklin, Henry F, Kym, Philip R, Carlson, Kathryn E, O'Neil, James P, Bonasera, Thomas A, Welch, Michael J, Katzenellenbogen, John A
Published in Journal of medicinal chemistry (30.04.1993)
Published in Journal of medicinal chemistry (30.04.1993)
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Journal Article
Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A(4) hydrolase
Kirkland, Thomas A., Adler, Marc, Bauman, John G., Chen, Ming, Haeggstrom, Jesper Z., King, Beverly, Kochanny, Monica J., Liang, Amy M., Mendoza, Lisa, Phillips, Gary B., Thunnissen, Marjolein, Trinh, Lan, Whitlow, Marc, Ye, Bin, Ye, Hong, Parkinson, John, Guilford, William J.
Published in Bioorganic & medicinal chemistry (01.05.2008)
Published in Bioorganic & medicinal chemistry (01.05.2008)
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Journal Article
Fluorine-substituted corticosteroids: Synthesis and evaluation as potential receptor-based imaging agents for positron emission tomography of the brain
Pomper, Martin G, Kochanny, Monica J, Thieme, Andrea M, Carlson, Kathryn E, Vanbrocklin, Henry F, Mathias, Carla J, Welch, Michael J, Katzenellenbogen, John A
Published in International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology (01.05.1992)
Published in International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology (01.05.1992)
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Journal Article
Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A sub(4) hydrolase
Kirkland, Thomas A, Adler, Marc, Bauman, John G, Chen, Ming, Haeggstroem, Jesper Z, King, Beverly, Kochanny, Monica J, Liang, Amy M, Mendoza, Lisa, Phillips, Gary B, Thunnissen, Marjolein, Trinh, Lan, Whitlow, Marc, Ye, Bin, Ye, Hong, Parkinson, John, Guilford, William J
Published in Bioorganic & medicinal chemistry (01.05.2008)
Published in Bioorganic & medicinal chemistry (01.05.2008)
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Journal Article
Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A 4 hydrolase
Kirkland, Thomas A., Adler, Marc, Bauman, John G., Chen, Ming, Haeggström, Jesper Z., King, Beverly, Kochanny, Monica J., Liang, Amy M., Mendoza, Lisa, Phillips, Gary B., Thunnissen, Marjolein, Trinh, Lan, Whitlow, Marc, Ye, Bin, Ye, Hong, Parkinson, John, Guilford, William J.
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Journal Article
DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE
Light, David, Claret, Emmanuel, Brown, Greg, Liang, Amy, Ye, Bin, Davey, David, Guilford, William, Parkinson, John, Kochanny, Monica J, Kirkland, Thomas, Wei, Guo Ping, Cleve, Arwed, Arnaiz, Damian O, Khim, Seock-Kyu
Year of Publication 10.08.2023
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Year of Publication 10.08.2023
Patent
Diamine derivatives as inhibitors of leukotriene A4 hydrolase
Light, David, Claret, Emmanuel, Brown, Greg, Liang, Amy, Ye, Bin, Davey, David, Guilford, William, Parkinson, John, Kochanny, Monica J, Kirkland, Thomas, Wei, Guo Ping, Cleve, Arwed, Arnaiz, Damian O, Khim, Seock-Kyu
Year of Publication 08.03.2022
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Year of Publication 08.03.2022
Patent
Design, Synthesis, and Biological Activity of Novel Factor Xa Inhibitors: 4-Aryloxy Substituents of 2,6-Diphenoxypyridines††See ref. 1
Ng, Howard P., Buckman, Brad O., Eagen, Keith A., Guilford, William J., Kochanny, Monica J., Mohan, Raju, Shaw, Kenneth J., Wu, Shung C., Lentz, Dao, Liang, Amy, Trinh, Lan, Ho, Elena, Smith, David, Subramanyam, Babu, Vergona, Ron, Walters, Janette, White, Kathy A., Sullivan, Mark E., Morrissey, Michael M., Phillips, Gary B.
Published in Bioorganic & medicinal chemistry (01.03.2002)
Published in Bioorganic & medicinal chemistry (01.03.2002)
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Journal Article
DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE
Light, David, Claret, Emmanuel, Brown, Greg, Liang, Amy, Ye, Bin, Davey, David, Guilford, William, Parkinson, John, Kochanny, Monica J, Kirkland, Thomas, Wei, Guo Ping, Cleve, Arwed, Arnaiz, Damian O, Khim, Seock-Kyu
Year of Publication 01.10.2020
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Year of Publication 01.10.2020
Patent