Mechanisms of acute axonal degeneration in the optic nerve in vivo
Knöferle, Johanna, Koch, Jan C, Ostendorf, Thomas, Michel, Uwe, Planchamp, Véronique, Vutova, Polya, Tönges, Lars, Stadelmann, Christine, Brück, Wolfgang, Bähr, Mathias, Lingor, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2010)
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Journal Article
MDS1 and EVI1 complex locus (MECOM): a novel candidate gene for hereditary hematological malignancies
Ripperger, Tim, Hofmann, Winfried, Koch, Jan C, Shirneshan, Katayoon, Haase, Detlef, Wulf, Gerald, Issing, Peter R, Karnebogen, Matthias, Schmidt, Gunnar, Auber, Bernd, Schlegelberger, Brigitte, Illig, Thomas, Zirn, Birgit, Steinemann, Doris
Published in Haematologica (Roma) (01.02.2018)
Published in Haematologica (Roma) (01.02.2018)
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Journal Article
Axonal degeneration as a therapeutic target in the CNS
Lingor, Paul, Koch, Jan C., Tönges, Lars, Bähr, Mathias
Published in Cell and tissue research (01.07.2012)
Published in Cell and tissue research (01.07.2012)
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Journal Article
Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration
Zhang, Jian-Nan, Michel, Uwe, Lenz, Christof, Friedel, Caroline C., Köster, Sarah, d’Hedouville, Zara, Tönges, Lars, Urlaub, Henning, Bähr, Mathias, Lingor, Paul, Koch, Jan C.
Published in Scientific reports (15.11.2016)
Published in Scientific reports (15.11.2016)
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Journal Article
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo
Saal, Kim-Ann, Koch, Jan C, Tatenhorst, Lars, Szegő, Éva M, Ribas, Vinicius Toledo, Michel, Uwe, Bähr, Mathias, Tönges, Lars, Lingor, Paul
Published in Neurobiology of disease (01.01.2015)
Published in Neurobiology of disease (01.01.2015)
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Journal Article
Neurochemical markers in CSF of adolescent and adult SMA patients undergoing nusinersen treatment
Wurster, Claudia D., Günther, René, Steinacker, Petra, Dreyhaupt, Jens, Wollinsky, Kurt, Uzelac, Zeljko, Witzel, Simon, Kocak, Tugrul, Winter, Benedikt, Koch, Jan C., Lingor, Paul, Petri, Susanne, Ludolph, Albert C., Hermann, Andreas, Otto, Markus
Published in Therapeutic advances in neurological disorders (2019)
Published in Therapeutic advances in neurological disorders (2019)
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Journal Article
Serum creatine kinase and creatinine in adult spinal muscular atrophy under nusinersen treatment
Freigang, Maren, Wurster, Claudia D., Hagenacker, Tim, Stolte, Benjamin, Weiler, Markus, Kamm, Christoph, Schreiber‐Katz, Olivia, Osmanovic, Alma, Petri, Susanne, Kowski, Alexander, Meyer, Thomas, Koch, Jan C., Cordts, Isabell, Deschauer, Marcus, Lingor, Paul, Aust, Elisa, Petzold, Daniel, Ludolph, Albert C., Falkenburger, Björn, Hermann, Andreas, Günther, René
Published in Annals of clinical and translational neurology (01.05.2021)
Published in Annals of clinical and translational neurology (01.05.2021)
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Journal Article
Tofersen decreases neurofilament levels supporting the pathogenesis of the SOD1 p.D91A variant in amyotrophic lateral sclerosis patients
Weishaupt, Jochen H., Körtvélyessy, Péter, Schumann, Peggy, Valkadinov, Ivan, Weyen, Ute, Hesebeck-Brinckmann, Jasper, Weishaupt, Kanchi, Endres, Matthias, Andersen, Peter M., Regensburger, Martin, Dreger, Marie, Koch, Jan C., Conrad, Julian, Meyer, Thomas
Published in Communications medicine (25.07.2024)
Published in Communications medicine (25.07.2024)
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Journal Article
Routine Cerebrospinal Fluid (CSF) Parameters in Patients With Spinal Muscular Atrophy (SMA) Treated With Nusinersen
Wurster, Claudia D., Koch, Jan C., Cordts, Isabell, Dreyhaupt, Jens, Otto, Markus, Uzelac, Zeljko, Witzel, Simon, Winter, Benedikt, Kocak, Tugrul, Schocke, Michael, Weydt, Patrick, Wollinsky, Kurt, Ludolph, Albert C., Deschauer, Marcus, Lingor, Paul, Tumani, Hayrettin, Hermann, Andreas, Günther, René
Published in Frontiers in neurology (07.11.2019)
Published in Frontiers in neurology (07.11.2019)
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Journal Article
Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro
Koch, Jan C, Solis, Gonzalo P, Bodrikov, Vsevolod, Michel, Uwe, Haralampieva, Deana, Shypitsyna, Aleksandra, Tönges, Lars, Bähr, Mathias, Lingor, Paul, Stuermer, Claudia A.O
Published in Neurobiology of disease (01.03.2013)
Published in Neurobiology of disease (01.03.2013)
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Journal Article
Glial fibrillary acidic protein in cerebrospinal fluid of patients with spinal muscular atrophy
Freigang, Maren, Steinacker, Petra, Wurster, Claudia D., Schreiber‐Katz, Olivia, Osmanovic, Alma, Petri, Susanne, Koch, Jan C., Rostásy, Kevin, Huss, André, Tumani, Hayrettin, Winter, Benedikt, Falkenburger, Björn, Ludolph, Albert C., Otto, Markus, Hermann, Andreas, Günther, René
Published in Annals of clinical and translational neurology (01.09.2022)
Published in Annals of clinical and translational neurology (01.09.2022)
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Journal Article
TGF-β 1 enhances neurite outgrowth via regulation of proteasome function and EFABP
Knöferle, Johanna, Ramljak, Sanja, Koch, Jan C, Tönges, Lars, Asif, Abdul R, Michel, Uwe, Wouters, Fred S, Heermann, Stephan, Krieglstein, Kerstin, Zerr, Inga, Bähr, Mathias, Lingor, Paul
Published in Neurobiology of disease (01.06.2010)
Published in Neurobiology of disease (01.06.2010)
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Journal Article
Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium-dependent manner
Koch, Jan C., Knöferle, Johanna, Tönges, Lars, Ostendorf, Thomas, Bähr, Mathias, Lingor, Paul
Published in Autophagy (01.07.2010)
Published in Autophagy (01.07.2010)
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Journal Article
Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study
Hagenacker, Tim, Wurster, Claudia D, Günther, René, Schreiber-Katz, Olivia, Osmanovic, Alma, Petri, Susanne, Weiler, Markus, Ziegler, Andreas, Kuttler, Josua, Koch, Jan C, Schneider, Ilka, Wunderlich, Gilbert, Schloss, Natalie, Lehmann, Helmar C, Cordts, Isabell, Deschauer, Marcus, Lingor, Paul, Kamm, Christoph, Stolte, Benjamin, Pietruck, Lena, Totzeck, Andreas, Kizina, Kathrin, Mönninghoff, Christoph, von Velsen, Otgonzul, Ose, Claudia, Reichmann, Heinz, Forsting, Michael, Pechmann, Astrid, Kirschner, Janbernd, Ludolph, Albert C, Hermann, Andreas, Kleinschnitz, Christoph
Published in Lancet neurology (01.04.2020)
Published in Lancet neurology (01.04.2020)
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Journal Article
Safety and Effectiveness of Long-term Intravenous Administration of Edaravone for Treatment of Patients With Amyotrophic Lateral Sclerosis
Witzel, Simon, Maier, André, Steinbach, Robert, Grosskreutz, Julian, Koch, Jan C, Sarikidi, Anastasia, Petri, Susanne, Günther, René, Wolf, Joachim, Hermann, Andreas, Prudlo, Johannes, Cordts, Isabell, Lingor, Paul, Löscher, Wolfgang N, Kohl, Zacharias, Hagenacker, Tim, Ruckes, Christian, Koch, Birgit, Spittel, Susanne, Günther, Kornelia, Michels, Sebastian, Dorst, Johannes, Meyer, Thomas, Ludolph, Albert C
Published in Archives of neurology (Chicago) (01.02.2022)
Published in Archives of neurology (Chicago) (01.02.2022)
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Journal Article
MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation
Doeppner, Thorsten R., Doehring, Maria, Bretschneider, Eva, Zechariah, Anil, Kaltwasser, Britta, Müller, Barbara, Koch, Jan C., Bähr, Mathias, Hermann, Dirk M., Michel, Uwe
Published in Acta neuropathologica (01.08.2013)
Published in Acta neuropathologica (01.08.2013)
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Journal Article
Neurofilament light chain in serum of adolescent and adult SMA patients under treatment with nusinersen
Wurster, Claudia D., Steinacker, Petra, Günther, René, Koch, Jan C., Lingor, Paul, Uzelac, Zeljko, Witzel, Simon, Wollinsky, Kurt, Winter, Benedikt, Osmanovic, Alma, Schreiber-Katz, Olivia, Al Shweiki, Rami, Ludolph, Albert C., Petri, Susanne, Hermann, Andreas, Otto, Markus
Published in Journal of neurology (2020)
Published in Journal of neurology (2020)
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Journal Article