Chronic neuropathic pain is accompanied by global changes in gene expression and shares pathobiology with neurodegenerative diseases
Wang, H, Sun, H, Della Penna, K, Benz, R.J, Xu, J, Gerhold, D.L, Holder, D.J, Koblan, K.S
Published in Neuroscience (01.01.2002)
Published in Neuroscience (01.01.2002)
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The effects of a novel histamine-3 receptor inverse agonist on essential tremor in comparison to stable levels of alcohol
Zoethout, R W M, Iannone, R, Bloem, B R, Palcza, J, Murphy, G, Chodakewitz, J, Buntinx, A, Gottesdiener, K, Marsilio, S, Rosen, L, van Dyck, K, Louis, E D, Cohen, A F, Schoemaker, R C, Tokita, S, Sato, N, Koblan, K S, Hargreaves, R H, Renger, Jj, van Gerven, J M A
Published in Journal of psychopharmacology (Oxford) (01.02.2012)
Published in Journal of psychopharmacology (Oxford) (01.02.2012)
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Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat
Oliver, K. R., Kane, S. A., Salvatore, C. A., Mallee, J. J., Kinsey, A. M., Koblan, K. S., Keyvan-Fouladi, N., Heavens, R. P., Wainwright, A., Jacobson, M., Dickerson, I. M., Hill, R. G.
Published in The European journal of neuroscience (01.08.2001)
Published in The European journal of neuroscience (01.08.2001)
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Assessment of human abuse potential of dasotraline compared to methylphenidate and placebo in recreational stimulant users
Koblan, K.S, Hopkins, S.C, Sarma, K, Gallina, N, Jin, F, Levy-Cooperman, N, Schoedel, K.A, Loebel, A
Published in Drug and alcohol dependence (01.02.2016)
Published in Drug and alcohol dependence (01.02.2016)
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Imidazole-containing diarylether and diarylsulfone inhibitors of farnesyl-protein transferase
Dinsmore, Christopher J., Williams, Theresa M., O'Neill, Timothy J., Liu, Dongming, Rands, Elaine, Culberson, J.Christopher, Lobell, Robert B., Koblan, Kenneth S., Kohl, Nancy E., Gibbs, Jackson B., Oliff, Allen I., Graham, Samuel L., Hartman, George D.
Published in Bioorganic & medicinal chemistry letters (06.12.1999)
Published in Bioorganic & medicinal chemistry letters (06.12.1999)
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2-Substituted Piperazines as Constrained Amino Acids. Application to the Synthesis of Potent, Non Carboxylic Acid Inhibitors of Farnesyltransferase
Williams, Theresa M, Ciccarone, Terrence M, MacTough, Suzanne C, Bock, Rhonda L, Conner, Michael W, Davide, Joseph P, Hamilton, Kelly, Koblan, Kenneth S, Kohl, Nancy E, Kral, Astrid M, Mosser, Scott D, Omer, Charles A, Pompliano, David L, Rands, Elaine, Schaber, Michael D, Shah, Daksha, Wilson, Francine R, Gibbs, Jackson B, Graham, Samuel L, Hartman, George D, Oliff, Allen I, Smith, Robert L
Published in Journal of medicinal chemistry (29.03.1996)
Published in Journal of medicinal chemistry (29.03.1996)
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Design and in Vivo Analysis of Potent Non-Thiol Inhibitors of Farnesyl Protein Transferase
Anthony, Neville J, Gomez, Robert P, Schaber, Micheal D, Mosser, Scott D, Hamilton, Kelly A, O'Neil, Timothy J, Koblan, Kenneth S, Graham, Samuel L, Hartman, George D, Shah, Daksha, Rands, Elaine, Kohl, Nancy E, Gibbs, Jackson B, Oliff, Allen I
Published in Journal of medicinal chemistry (26.08.1999)
Published in Journal of medicinal chemistry (26.08.1999)
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Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase
Ciccarone, Terrence M., MacTough, Suzanne C., Williams, Theresa M., Dinsmore, Christopher J., O'Neill, Timothy J., Shah, Daksha, Culberson, J.Christopher, Koblan, Kenneth S., Kohl, Nancy E., Gibbs, Jackson B., Oliff, Allen I., Graham, Samuel L., Hartman, George D.
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
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Characterization and localization of a human serine racemase
Xia, Menghang, Liu, Yuan, Figueroa, David J., Chiu, Chi-Sung, Wei, Nan, Lawlor, Ann-Marie, Lu, Ping, Sur, Cyrille, Koblan, Ken S., Connolly, Thomas M.
Published in Brain research. Molecular brain research. (18.06.2004)
Published in Brain research. Molecular brain research. (18.06.2004)
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Clavaric Acid and Steroidal Analogues as Ras- and FPP-Directed Inhibitors of Human Farnesyl-Protein Transferase
Lingham, Russell B, Silverman, Keith C, Jayasuriya, Hiranthi, Kim, B. Moon, Amo, Suzanne E, Wilson, Francine R, Rew, Deborah J, Schaber, Michael D, Bergstrom, James D, Koblan, Kenneth S, Graham, Samuel L, Kohl, Nancy E, Gibbs, Jackson B, Singh, Sheo B
Published in Journal of medicinal chemistry (05.11.1998)
Published in Journal of medicinal chemistry (05.11.1998)
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Journal Article
N-Arylalkyl Pseudopeptide Inhibitors of Farnesyltransferase
deSolms, S. Jane, Giuliani, Elizabeth A, Graham, Samuel L, Koblan, Kenneth S, Kohl, Nancy E, Mosser, Scott D, Oliff, Allen I, Pompliano, David L, Rands, Elaine, Scholz, Thomas H, Wiscount, Catherine M, Gibbs, Jackson B, Smith, Robert L
Published in Journal of medicinal chemistry (02.07.1998)
Published in Journal of medicinal chemistry (02.07.1998)
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Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl :protein transferase inhibitor
OMER, C. A, ZUNXUAN CHEN, DAVIDE, J. P, ELLIS, M. S, GIBBS, J. B, GREENBERG, I, HAMILTON, K, KOBLAN, K. S, KRAL, A. M, DONGMING LIU, LOBELL, R. B, MILLER, P. J, DIEHL, R. E, MOSSER, S. D, O'NEILL, T. J, RANDS, E, SCHABER, M. D, SENDERAK, E. T, OLIFF, A, KOHL, N. E, CONNER, M. W, CHEN, H. Y, TRUMBAUER, M. E, GOPAL-TRUTER, S, SEEBURGER, G, BHIMNATHWALA, H, ABRAMS, M. T
Published in Cancer research (Chicago, Ill.) (15.05.2000)
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Published in Cancer research (Chicago, Ill.) (15.05.2000)
Journal Article
NMR studies of novel inhibitors bound to farnesyl‐protein transferase
Koblan, Kenneth S., Mosser, Scott D., Omer, Charles A., Christopher Culberson, J., Jane Desolms, S., Giuliani, Elizabeth A., Pitzenberger, Steven M., Bogusky, Michael J.
Published in Protein science (01.04.1995)
Published in Protein science (01.04.1995)
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Farnesyltransferase inhibitors and anti-Ras therapy
Gibbs, J B, Kohl, N E, Koblan, K S, Omer, C A, Sepp-Lorenzino, L, Rosen, N, Anthony, N J, Conner, M W, deSolms, S J, Williams, T M, Graham, S L, Hartman, G D, Oliff, A
Published in Breast cancer research and treatment (01.01.1996)
Published in Breast cancer research and treatment (01.01.1996)
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Klebsiella pneumoniae nifM gene product is required for stabilization and activation of nitrogenase iron protein in Escherichia coli
Howard, K S, McLean, P A, Hansen, F B, Lemley, P V, Koblan, K S, Orme-Johnson, W H
Published in The Journal of biological chemistry (15.01.1986)
Published in The Journal of biological chemistry (15.01.1986)
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Farnesyltransferase inhibitors: a new class of cancer chemotherapeutics
Koblan, K S, Kohl, N E, Omer, C A, Anthony, N J, Conner, M W, deSolms, S J, Williams, T M, Graham, S L, Hartman, G D, Oliff, A, Gibbs, J B
Published in Biochemical Society transactions (01.08.1996)
Published in Biochemical Society transactions (01.08.1996)
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