Calcium-Voltage Coupling in the Genesis of Early and Delayed Afterdepolarizations in Cardiac Myocytes
Song, Zhen, Ko, Christopher Y., Nivala, Michael, Weiss, James N., Qu, Zhilin
Published in Biophysical journal (21.04.2015)
Published in Biophysical journal (21.04.2015)
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Journal Article
Two-hit mechanism of cardiac arrhythmias in diabetic hyperglycaemia: reduced repolarization reserve, neurohormonal stimulation, and heart failure exacerbate susceptibility
Hegyi, Bence, Ko, Christopher Y, Bossuyt, Julie, Bers, Donald M
Published in Cardiovascular research (17.12.2021)
Published in Cardiovascular research (17.12.2021)
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Journal Article
Criticality in Intracellular Calcium Signaling in Cardiac Myocytes
Nivala, Michael, Ko, Christopher Y., Nivala, Melissa, Weiss, James N., Qu, Zhilin
Published in Biophysical journal (06.06.2012)
Published in Biophysical journal (06.06.2012)
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Journal Article
CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to Proarrhythmia
Hegyi, Bence, Fasoli, Anna, Ko, Christopher Y., Van, Benjamin W., Alim, Chidera C., Shen, Erin Y., Ciccozzi, Marisa M., Tapa, Srinivas, Ripplinger, Crystal M., Erickson, Jeffrey R., Bossuyt, Julie, Bers, Donald M.
Published in Circulation research (25.06.2021)
Published in Circulation research (25.06.2021)
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Journal Article
S-nitrosylation of CaMKII cys273 suppresses CaMKII activation and translocation within cardiac myocytes
Alim, Chidera C., Ko, Christopher Y., Bossuyt, Julie, Bers, Donald M.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
SparkMaster 2: A New Software for Automatic Analysis of Calcium Spark Data
Tomek, Jakub, Nieves-Cintron, Madeline, Navedo, Manuel F, Ko, Christopher Y, Bers, Donald M
Published in Circulation research (01.09.2023)
Published in Circulation research (01.09.2023)
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Journal Article
Cardiomyocyte Na+ and Ca2+ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors
Hegyi, Bence, Pölönen, Risto-Pekka, Hellgren, Kim T., Ko, Christopher Y., Ginsburg, Kenneth S., Bossuyt, Julie, Mercola, Mark, Bers, Donald M.
Published in Basic research in cardiology (01.12.2021)
Published in Basic research in cardiology (01.12.2021)
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Journal Article
Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation
Pezhouman, Arash, Singh, Neha, Song, Zhen, Nivala, Michael, Eskandari, Anahita, Cao, Hong, Bapat, Aneesh, Ko, Christopher Y, Nguyen, Thao P, Qu, Zhilin, Karagueuzian, Hrayr S, Weiss, James N
Published in Circulation (New York, N.Y.) (20.10.2015)
Published in Circulation (New York, N.Y.) (20.10.2015)
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Journal Article
Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes
Sdek, Patima, Zhao, Peng, Wang, Yaping, Huang, Chang-Jiang, Ko, Christopher Y, Butler, Peter C, Weiss, James N, Maclellan, W Robb
Published in The Journal of cell biology (08.08.2011)
Published in The Journal of cell biology (08.08.2011)
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Journal Article
Differential sex-dependent susceptibility to diastolic dysfunction and arrhythmia in cardiomyocytes from obese diabetic heart failure with preserved ejection fraction model
Mira Hernandez, Juliana, Shen, Erin Y, Ko, Christopher Y, Hourani, Zaynab, Spencer, Emily R, Smoliarchuk, Daria, Bossuyt, Julie, Granzier, Henk, Bers, Donald M, Hegyi, Bence
Published in Cardiovascular research (06.05.2024)
Published in Cardiovascular research (06.05.2024)
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Journal Article
CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes
Simon, Mitchell, Ko, Christopher Y., Rebbeck, Robyn T., Baidar, Sonya, Cornea, Razvan L., Bers, Donald M.
Published in Journal of molecular and cellular cardiology (01.12.2021)
Published in Journal of molecular and cellular cardiology (01.12.2021)
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Journal Article
Synergistic FRET assays for drug discovery targeting RyR2 channels
Rebbeck, RobynT, Ginsburg, Kenneth S., Ko, Christopher Y., Fasoli, Anna, Rusch, Katherine, Cai, George F., Dong, Xiaoqiong, Thomas, David D., Bers, Donald M., Cornea, Razvan L.
Published in Journal of molecular and cellular cardiology (01.07.2022)
Published in Journal of molecular and cellular cardiology (01.07.2022)
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Journal Article
Empagliflozin and ROS-CaMKII-late sodium current signaling in heart failure with preserved ejection fraction
Hegyi, Bence, Mira Hernandez, Juliana, Shen, Erin Y., Spencer, Emily R., Smoliarchuk, Daria, Edwards, Tory A., Ko, Christopher Y., Bossuyt, Julie, Bers, Donald M.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Post-translational modification-dependent regulation of CaMKII-delta conformation in live cardiac myocytes
Ko, Christopher Y., Le, Leann T., Smoliarchuk, Daria, Baidar, Sonya, Tomek, Jakub, Alim, Chidera C., Mira Hernandez, Juliana, Martin, Jody L., Bers, Donald M.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Pkd1 is necessary for full cardiac AngII-induced hypertrophy but not for full acute AngII-induced calcium handling changes
Mira Hernandez, Juliana, Ko, Christopher Y., Mandel, Avery, Shen, Erin Y., Christensen, Ashley R., Bossuyt, Julie, Bers, Donald M.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Nitrosylation of cardiac CaMKII at Cys290 mediates mechanical afterload-induced increases in Ca 2+ transient and Ca 2+ sparks
Alim, Chidera C, Ko, Christopher Y, Mira Hernandez, Juliana, Shen, Erin Y, Baidar, Sonya, Chen-Izu, Ye, Bers, Donald M, Bossuyt, Julie
Published in The Journal of physiology (01.11.2022)
Published in The Journal of physiology (01.11.2022)
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Journal Article
Nitrosylation of cardiac CaMKII at Cys290 mediates mechanical afterload‐induced increases in Ca2+ transient and Ca2+ sparks
Alim, Chidera C., Ko, Christopher Y., Mira Hernandez, Juliana, Shen, Erin Y., Baidar, Sonya, Chen‐Izu, Ye, Bers, Donald M., Bossuyt, Julie
Published in The Journal of physiology (01.11.2022)
Published in The Journal of physiology (01.11.2022)
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Journal Article
Cardiac Protein Kinase D1 ablation alters the myocytes β-adrenergic response
Mira Hernandez, Juliana, Ko, Christopher Y., Mandel, Avery R., Shen, Erin Y., Baidar, Sonya, Christensen, Ashley R., Hellgren, Kim, Morotti, Stefano, Martin, Jody L., Hegyi, Bence, Bossuyt, Julie, Bers, Donald M.
Published in Journal of molecular and cellular cardiology (01.07.2023)
Published in Journal of molecular and cellular cardiology (01.07.2023)
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Journal Article
Multiscale Determinants of Delayed Afterdepolarization Amplitude in Cardiac Tissue
Ko, Christopher Y., Liu, Michael B., Song, Zhen, Qu, Zhilin, Weiss, James N.
Published in Biophysical journal (09.05.2017)
Published in Biophysical journal (09.05.2017)
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Journal Article
Diabetes and Excess Aldosterone Promote Heart Failure With Preserved Ejection Fraction
Hegyi, Bence, Mira Hernandez, Juliana, Ko, Christopher Y, Hong, Junyoung, Shen, Erin Y, Spencer, Emily R, Smoliarchuk, Daria, Navedo, Manuel F, Bers, Donald M, Bossuyt, Julie
Published in Journal of the American Heart Association (06.12.2022)
Published in Journal of the American Heart Association (06.12.2022)
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