On the lag phase in amyloid fibril formation
Arosio, Paolo, Knowles, Tuomas P. J, Linse, Sara
Published in Physical chemistry chemical physics : PCCP (01.01.2015)
Published in Physical chemistry chemical physics : PCCP (01.01.2015)
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Journal Article
From Protein Building Blocks to Functional Materials
Shen, Yi, Levin, Aviad, Kamada, Ayaka, Toprakcioglu, Zenon, Rodriguez-Garcia, Marc, Xu, Yufan, Knowles, Tuomas P. J
Published in ACS nano (27.04.2021)
Published in ACS nano (27.04.2021)
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Journal Article
Half a century of amyloids: past, present and future
Ke, Pu Chun, Zhou, Ruhong, Serpell, Louise C, Riek, Roland, Knowles, Tuomas P. J, Lashuel, Hilal A, Gazit, Ehud, Hamley, Ian W, Davis, Thomas P, Fändrich, Marcus, Otzen, Daniel Erik, Chapman, Matthew R, Dobson, Christopher M, Eisenberg, David S, Mezzenga, Raffaele
Published in Chemical Society reviews (07.08.2020)
Published in Chemical Society reviews (07.08.2020)
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Journal Article
Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
Michaels, Thomas C. T., Šarić, Andela, Curk, Samo, Bernfur, Katja, Arosio, Paolo, Meisl, Georg, Dear, Alexander J., Cohen, Samuel I. A., Dobson, Christopher M., Vendruscolo, Michele, Linse, Sara, Knowles, Tuomas P. J.
Published in Nature chemistry (01.05.2020)
Published in Nature chemistry (01.05.2020)
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Journal Article
Learning the molecular grammar of protein condensates from sequence determinants and embeddings
Saar, Kadi L., Morgunov, Alexey S., Qi, Runzhang, Arter, William E., Krainer, Georg, Lee, Alpha A., Knowles, Tuomas P. J.
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2021)
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Journal Article
The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils
Thacker, Dev, Sanagavarapu, Kalyani, Frohm, Birgitta, Meisl, Georg, Knowles, Tuomas P. J., Linse, Sara
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2020)
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Journal Article
Determination of Polypeptide Conformation with Nanoscale Resolution in Water
Ramer, Georg, Ruggeri, Francesco Simone, Levin, Aviad, Knowles, Tuomas P. J, Centrone, Andrea
Published in ACS nano (24.07.2018)
Published in ACS nano (24.07.2018)
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Journal Article
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
Krainer, Georg, Welsh, Timothy J., Joseph, Jerelle A., Espinosa, Jorge R., Wittmann, Sina, de Csilléry, Ella, Sridhar, Akshay, Toprakcioglu, Zenon, Gudiškytė, Giedre, Czekalska, Magdalena A., Arter, William E., Guillén-Boixet, Jordina, Franzmann, Titus M., Qamar, Seema, George-Hyslop, Peter St, Hyman, Anthony A., Collepardo-Guevara, Rosana, Alberti, Simon, Knowles, Tuomas P. J.
Published in Nature communications (17.02.2021)
Published in Nature communications (17.02.2021)
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Journal Article
Conformational Expansion of Tau in Condensates Promotes Irreversible Aggregation
Wen, Jitao, Hong, Liu, Krainer, Georg, Yao, Qiong-Qiong, Knowles, Tuomas P. J, Wu, Si, Perrett, Sarah
Published in Journal of the American Chemical Society (25.08.2021)
Published in Journal of the American Chemical Society (25.08.2021)
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Journal Article
Molecular mechanisms of protein aggregation from global fitting of kinetic models
Meisl, Georg, Kirkegaard, Julius B, Arosio, Paolo, Michaels, Thomas C T, Vendruscolo, Michele, Dobson, Christopher M, Linse, Sara, Knowles, Tuomas P J
Published in Nature protocols (01.02.2016)
Published in Nature protocols (01.02.2016)
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Journal Article
The amyloid state and its association with protein misfolding diseases
Knowles, Tuomas P. J., Vendruscolo, Michele, Dobson, Christopher M.
Published in Nature reviews. Molecular cell biology (01.06.2014)
Published in Nature reviews. Molecular cell biology (01.06.2014)
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Journal Article
Physical determinants of the self-replication of protein fibrils
Šarić, Anđela, Buell, Alexander K., Meisl, Georg, Michaels, Thomas C. T., Dobson, Christopher M., Linse, Sara, Knowles, Tuomas P. J., Frenkel, Daan
Published in Nature physics (01.09.2016)
Published in Nature physics (01.09.2016)
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Journal Article
Expanding the Solvent Chemical Space for Self-Assembly of Dipeptide Nanostructures
Mason, Thomas O, Chirgadze, Dimitri Y, Levin, Aviad, Adler-Abramovich, Lihi, Gazit, Ehud, Knowles, Tuomas P. J, Buell, Alexander K
Published in ACS nano (25.02.2014)
Published in ACS nano (25.02.2014)
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Journal Article
Crucial role of nonspecific interactions in amyloid nucleation
Šarić, Anđela, Chebaro, Yassmine C., Knowles, Tuomas P. J., Frenkel, Daan
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2014)
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Journal Article
Label-Free Analysis of Protein Aggregation and Phase Behavior
Toprakcioglu, Zenon, Challa, Pavankumar, Xu, Catherine, Knowles, Tuomas P. J
Published in ACS nano (24.12.2019)
Published in ACS nano (24.12.2019)
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Journal Article
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Shen, Yi, Ruggeri, Francesco Simone, Vigolo, Daniele, Kamada, Ayaka, Qamar, Seema, Levin, Aviad, Iserman, Christiane, Alberti, Simon, George-Hyslop, Peter St, Knowles, Tuomas P. J.
Published in Nature nanotechnology (01.10.2020)
Published in Nature nanotechnology (01.10.2020)
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