Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study
Swain, Sandra M, Dr, Kim, Sung-Bae, MD, Cortés, Javier, MD, Ro, Jungsil, MD, Semiglazov, Vladimir, MD, Campone, Mario, MD, Ciruelos, Eva, MD, Ferrero, Jean-Marc, MD, Schneeweiss, Andreas, MD, Knott, Adam, PhD, Clark, Emma, MSc, Ross, Graham, FFPM, Benyunes, Mark C, MD, Baselga, José, MD
Published in The lancet oncology (01.05.2013)
Published in The lancet oncology (01.05.2013)
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Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer
Baselga, José, Cortés, Javier, Kim, Sung-Bae, Im, Seock-Ah, Hegg, Roberto, Im, Young-Hyuck, Roman, Laslo, Pedrini, José Luiz, Pienkowski, Tadeusz, Knott, Adam, Clark, Emma, Benyunes, Mark C., Ross, Graham, Swain, Sandra M.
Published in The New England journal of medicine (12.01.2012)
Published in The New England journal of medicine (12.01.2012)
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Event-Free Survival in Patients with Early HER2-Positive Breast Cancer with a Pathological Complete Response after HER2-Targeted Therapy: A Pooled Analysis
Swain, Sandra M, Macharia, Harrison, Cortes, Javier, Dang, Chau, Gianni, Luca, Hurvitz, Sara A, Jackisch, Christian, Schneeweiss, Andreas, Slamon, Dennis, Valagussa, Pinuccia, du Toit, Yolande, Heinzmann, Dominik, Knott, Adam, Song, Chunyan, Cortazar, Patricia
Published in Cancers (01.10.2022)
Published in Cancers (01.10.2022)
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Alterations in Thin Filament Regulation Induced by a Human Cardiac Troponin T Mutant That Causes Dilated Cardiomyopathy Are Distinct from Those Induced by Troponin T Mutants That Cause Hypertrophic Cardiomyopathy
Robinson, Paul, Mirza, Mahmooda, Knott, Adam, Abdulrazzak, Hassan, Willott, Ruth, Marston, Steven, Watkins, Hugh, Redwood, Charles
Published in The Journal of biological chemistry (25.10.2002)
Published in The Journal of biological chemistry (25.10.2002)
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In vitro Motility Analysis of Thin Filaments from Failing and Non-failing Human Heart: Troponin from Failing Human Hearts Induces Slower Filament Sliding and Higher Ca2+ Sensitivity
Knott, Adam, Purcell, Ian, Marston, Steven
Published in Journal of molecular and cellular cardiology (01.04.2002)
Published in Journal of molecular and cellular cardiology (01.04.2002)
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Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer
von Minckwitz, Gunter, Procter, Marion, de Azambuja, Evandro, Zardavas, Dimitrios, Benyunes, Mark, Viale, Giuseppe, Suter, Thomas, Arahmani, Amal, Rouchet, Nathalie, Clark, Emma, Knott, Adam, Lang, Istvan, Levy, Christelle, Yardley, Denise A, Bines, Jose, Gelber, Richard D, Piccart, Martine, Baselga, Jose
Published in The New England journal of medicine (13.07.2017)
Published in The New England journal of medicine (13.07.2017)
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Journal Article
Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer
Baselga, José, Cortés, Javier, Kim, Sung-Bae, Im, Young-Hyuck, Im, Seock-Ah, Hegg, Roberto, Roman, Laslo, Pedrini, José Luiz, Pienkowski, Tadeusz, Knott, Adam, Clark, Emma, Benyunes, Mark C, Ross, Graham, Swain, Sandra M
Published in The New England journal of medicine (12.01.2012)
Published in The New England journal of medicine (12.01.2012)
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Pertuzumab, trastuzumab, and docetaxel for Chinese patients with previously untreated HER2-positive locally recurrent or metastatic breast cancer (PUFFIN): final analysis of a phase III, randomized, double-blind, placebo-controlled study
Xu, Binghe, Li, Wei, Zhang, Qingyuan, Li, Qiao, Wang, Xiaojia, Li, Huiping, Sun, Tao, Yin, Yongmei, Zheng, Hong, Feng, Jifeng, Zhu, Huaqi, Siddiqui, Asna, Macharia, Harrison, Knott, Adam
Published in Breast cancer research and treatment (01.02.2023)
Published in Breast cancer research and treatment (01.02.2023)
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Abstract P3-13-04: Clinical features and genetic alterations in patients (pts) with HER2-positive breast cancer (BC) and central nervous system (CNS) metastases (mets) in the real world
Dhillon, Preet K., Lambert, Peter, Sanglier, Thibaut, Knott, Adam, Restuccia, Eleonora, de Haas, Sanne L., Lambertini, Chiara
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Abstract P1-18-14: Use of pertuzumab in combination with taxanes for HER2+ metastatic breast cancer: Analysis of U.S. electronic health records
Polito, Letizia, Shim, Jinjoo, Toit, Yolande Du, Do, Thy, Knott, Adam, Sanglier, Thibaut
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Cardiac Tolerability of Pertuzumab Plus Trastuzumab Plus Docetaxel in Patients With HER2‐Positive Metastatic Breast Cancer in CLEOPATRA: A Randomized, Double‐Blind, Placebo‐Controlled Phase III Study
Swain, Sandra M., Ewer, Michael S., Cortés, Javier, Amadori, Dino, Miles, David, Knott, Adam, Clark, Emma, Benyunes, Mark C., Ross, Graham, Baselga, José
Published in The oncologist (Dayton, Ohio) (01.03.2013)
Published in The oncologist (Dayton, Ohio) (01.03.2013)
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Diversity, inclusion, and patient (pt)-centricity in the randomized, double-blind, phase III ASTEFANIA study of ado-trastuzumab emtansine (T-DM1) ± atezolizumab in pts with HER2-positive early breast cancer (EBC) with residual invasive disease after preoperative chemotherapy and anti-HER2 therapy
Rogerson, Sarah, Turner, Howard, Bilkhu, Angela, Monturus, Estefania, Knott, Adam, Restuccia, Eleonora, Quashie, Nigel, Wheatley, Duncan, Gilham, Leslie, Hurvitz, Sara A., Schmid, Peter, Bachelot, Thomas, Bianchini, Giampaolo, Harbeck, Nadia, Loi, Sherene, Park, Yeon Hee, Prat, Aleix, Simkins, Tracy
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Treatment of older patients with HER2-positive metastatic breast cancer with pertuzumab, trastuzumab, and docetaxel: subgroup analyses from a randomized, double-blind, placebo-controlled phase III trial (CLEOPATRA)
Miles, David, Baselga, José, Amadori, Dino, Sunpaweravong, Patrapim, Semiglazov, Vladimir, Knott, Adam, Clark, Emma, Ross, Graham, Swain, Sandra M.
Published in Breast cancer research and treatment (01.11.2013)
Published in Breast cancer research and treatment (01.11.2013)
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Journal Article
Safety Profile of Pertuzumab With Trastuzumab and Docetaxel in Patients From Asia With Human Epidermal Growth Factor Receptor 2‐Positive Metastatic Breast Cancer: Results From the Phase III Trial CLEOPATRA
Swain, Sandra M., Im, Young‐Hyuck, Im, Seock‐Ah, Chan, Valorie, Miles, David, Knott, Adam, Clark, Emma, Ross, Graham, Baselga, José
Published in The oncologist (Dayton, Ohio) (01.07.2014)
Published in The oncologist (Dayton, Ohio) (01.07.2014)
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ASTEFANIA: adjuvant ado-trastuzumab emtansine and atezolizumab for high-risk, HER2-positive breast cancer
Hurvitz, Sara A, Bachelot, Thomas, Bianchini, Giampaolo, Harbeck, Nadia, Loi, Sherene, Park, Yeon Hee, Prat, Aleix, Gilham, Leslie, Boulet, Thomas, Gochitashvili, Nino, Monturus, Estefania, Lambertini, Chiara, Nyawira, Beatrice, Knott, Adam, Restuccia, Eleonora, Schmid, Peter
Published in Future oncology (London, England) (01.10.2022)
Published in Future oncology (London, England) (01.10.2022)
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Abstract P1-18-05: Subcutaneous trastuzumab and hyaluronidase-oysk with intravenous pertuzumab and docetaxel in HER2-positive advanced breast cancer: Final analysis of the phase IIIb, multicenter, open-label, single-arm MetaPHER study
Kümmel, Sherko, Tondini, Carlo A, Abraham, Jacinta, Nowecki, Zbigniew, Itrych, Bartosz, Hitre, Erika, Karaszewska, Bogusława, Juarez, Alejandro, Morales-Vásquez, Flavia, García, Jose Manuel Pérez, Cardona-Huerta, Servando, Benyunes, Mark, Restuccia, Eleonora, Knott, Adam, Monturus, Estefanía, Sequi, Marco, Martín, Miguel
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Abstract P1-18-01: Risk of recurrence and death in patients with early HER2-positive breast cancer who achieve a pathological complete response (pCR) after different types of HER2-targeted therapy: A retrospective exploratory analysis
Swain, Sandra M, Macharia, Harrison, Cortes, Javier, Dang, Chau, Gianni, Luca, Hurvitz, Sara, Jackisch, Christian, Schneeweiss, Andreas, Slamon, Dennis, Valagussa, Pinuccia, du Toit, Yolande, Heinzmann, Dominik, Knott, Adam, Song, Chunyan, Cortazar, Patricia
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Abstract P2-11-07: Association of PIK3CA mutations with efficacy in HER2-positive first-line metastatic breast cancer: a meta-analysis
Swain, Sandra, Cortés, Javier, Xu, Binghe, Lambertini, Chiara, Essioux, Laurent, Knott, Adam, Restuccia, Eleonora, Madjar, Katrin, De Haas, Sanne Lysbet
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
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Abstract GS03-12: Phase III study of adjuvant ado-trastuzumab emtansine vs trastuzumab for residual invasive HER2-positive early breast cancer after neoadjuvant chemotherapy and HER2-targeted therapy: KATHERINE final IDFS and updated OS analysis
Loibl, Sibylle, Mano, Max, Untch, Michael, Huang, Chiun-Shen, Mamounas, Eleftherios, Wolmark, Norman, Knott, Adam, Siddiqui, Asna, Boulet, Thomas, Nyawira, Beatrice, Restuccia, Eleonora, Geyer, Charles
Published in Cancer research (Chicago, Ill.) (02.05.2024)
Published in Cancer research (Chicago, Ill.) (02.05.2024)
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