Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes
Eschenhagen, Thomas, Mummery, Christine, Knollmann, Bjorn C
Published in Cardiovascular research (01.04.2015)
Published in Cardiovascular research (01.04.2015)
Get full text
Journal Article
Animal Models to Study Cardiac Arrhythmias
Blackwell, Daniel J, Schmeckpeper, Jeffrey, Knollmann, Bjorn C
Published in Circulation research (10.06.2022)
Published in Circulation research (10.06.2022)
Get full text
Journal Article
Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies
Wu, Joseph C, Garg, Priyanka, Yoshida, Yoshinori, Yamanaka, Shinya, Gepstein, Lior, Hulot, Jean-Sébastien, Knollmann, Björn C, Schwartz, Peter J
Published in Circulation research (30.08.2019)
Published in Circulation research (30.08.2019)
Get full text
Journal Article
Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS
Hamilton, Shanna, Terentyeva, Radmila, Martin, Benjamin, Perger, Fruzsina, Li, Jiaoni, Stepanov, Andrei, Bonilla, Ingrid M., Knollmann, Björn C., Radwański, Przemyslaw B., Györke, Sandor, Belevych, Andriy E., Terentyev, Dmitry
Published in Basic research in cardiology (01.07.2020)
Published in Basic research in cardiology (01.07.2020)
Get full text
Journal Article
Thyroid and Glucocorticoid Hormones Promote Functional T-Tubule Development in Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes
Parikh, Shan S, Blackwell, Daniel J, Gomez-Hurtado, Nieves, Frisk, Michael, Wang, Lili, Kim, Kyungsoo, Dahl, Christen P, Fiane, Arnt, Tønnessen, Theis, Kryshtal, Dmytro O, Louch, William E, Knollmann, Bjorn C
Published in Circulation research (08.12.2017)
Published in Circulation research (08.12.2017)
Get full text
Journal Article
Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes
Feaster, Tromondae K, Cadar, Adrian G, Wang, Lili, Williams, Charles H, Chun, Young Wook, Hempel, Jonathan E, Bloodworth, Nathaniel, Merryman, W David, Lim, Chee Chew, Wu, Joseph C, Knollmann, Björn C, Hong, Charles C
Published in Circulation research (04.12.2015)
Published in Circulation research (04.12.2015)
Get full text
Journal Article
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans
Roach, Daniel E, Chopra, Nagesh, Watanabe, Hiroshi, Hwang, Hyun Seok, Duff, Henry J, Wilde, Arthur A M, Knollmann, Björn C, Roden, Dan M, Laver, Derek, Davies, Sean S
Published in Nature medicine (01.04.2009)
Published in Nature medicine (01.04.2009)
Get full text
Journal Article
RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT
Kryshtal, Dmytro O, Blackwell, Daniel J, Egly, Christian L, Smith, Abigail N, Batiste, Suzanne M, Johnston, Jeffrey N, Laver, Derek R, Knollmann, Bjorn C
Published in Circulation research (05.02.2021)
Published in Circulation research (05.02.2021)
Get full text
Journal Article
The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of NaV1.5 and RyR2 function
Johnson, Christopher N., Pattanayek, Rekha, Potet, Franck, Rebbeck, Robyn T., Blackwell, Daniel J., Nikolaienko, Roman, Sequeira, Vasco, Le Meur, Remy, Radwański, Przemysław B., Davis, Jonathan P., Zima, Aleksey V., Cornea, Razvan L., Damo, Steven M., Györke, Sandor, George, Alfred L., Knollmann, Björn C.
Published in Cell calcium (Edinburgh) (01.09.2019)
Published in Cell calcium (Edinburgh) (01.09.2019)
Get full text
Journal Article
Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts
van Opbergen, Chantal J M, Bagwan, Navratan, Maurya, Svetlana R, Kim, Joon-Chul, Smith, Abigail N, Blackwell, Daniel J, Johnston, Jeffrey N, Knollmann, Björn C, Cerrone, Marina, Lundby, Alicia, Delmar, Mario
Published in Circulation (New York, N.Y.) (10.05.2022)
Published in Circulation (New York, N.Y.) (10.05.2022)
Get full text
Journal Article
Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension
Barbaro, Natalia R., Foss, Jason D., Kryshtal, Dmytro O., Tsyba, Nikita, Kumaresan, Shivani, Xiao, Liang, Mernaugh, Raymond L., Itani, Hana A., Loperena, Roxana, Chen, Wei, Dikalov, Sergey, Titze, Jens M., Knollmann, Bjorn C., Harrison, David G., Kirabo, Annet
Published in Cell reports (Cambridge) (24.10.2017)
Published in Cell reports (Cambridge) (24.10.2017)
Get full text
Journal Article
Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy
Marchiano, Silvia, Nakamura, Kenta, Reinecke, Hans, Neidig, Lauren, Lai, Michael, Kadota, Shin, Perbellini, Filippo, Yang, Xiulan, Klaiman, Jordan M., Blakely, Leslie P., Karbassi, Elaheh, Fields, Paul A., Fenix, Aidan M., Beussman, Kevin M., Jayabalu, Anu, Kalucki, Faith A., Potter, Jennifer C., Futakuchi-Tsuchida, Akiko, Weber, Gerhard J., Dupras, Sarah, Tsuchida, Hiroshi, Pabon, Lil, Wang, Lili, Knollmann, Björn C., Kattman, Steven, Thies, R. Scott, Sniadecki, Nathan, MacLellan, W. Robb, Bertero, Alessandro, Murry, Charles E.
Published in Cell stem cell (06.04.2023)
Published in Cell stem cell (06.04.2023)
Get full text
Journal Article
SR-Mitochondria Crosstalk Shapes Ca Signalling to Impact Pathophenotype in Disease Models Marked by Dysregulated Intracellular Ca Release
Tow, Brian D, Deb, Arpita, Neupane, Shraddha, Patel, Shuchi M, Reed, Meagan, Loper, Anna-Beth, Eliseev, Roman A, Knollmann, Björn C, Györke, Sándor, Liu, Bin
Published in Cardiovascular research (21.10.2022)
Published in Cardiovascular research (21.10.2022)
Get full text
Journal Article
The role of mitochondrial-associated-membranes in Ca-dependent arrhythmias
Deb, Arpita, Adekanye, Oluwabori, Knollmann, Bjorn C., Zhou, Lufang, Davis, Jonathan P., Liu, Bin
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
Get full text
Journal Article
Ryanodine receptor inhibition with acute dantrolene treatment reduces arrhythmia susceptibility in human hearts
George, Sharon A, Brennan-McLean, Jaclyn A, Trampel, Katy A, Rytkin, Eric, Faye, N Rokhaya, Knollmann, Björn C, Efimov, Igor R
Published in American journal of physiology. Heart and circulatory physiology (01.10.2023)
Published in American journal of physiology. Heart and circulatory physiology (01.10.2023)
Get full text
Journal Article
A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient KV11.1 (hERG) Variants
Egly, Christian L, Blackwell, Daniel J, Schmeckpeper, Jeffrey, Delisle, Brian P, Weaver, C David, Knollmann, Björn C
Published in Molecular pharmacology (01.04.2022)
Published in Molecular pharmacology (01.04.2022)
Get full text
Journal Article