In Vitro Evidence for Immune-Modulatory Properties of Non-Digestible Oligosaccharides: Direct Effect on Human Monocyte Derived Dendritic Cells
Lehmann, Sarah, Hiller, Julia, van Bergenhenegouwen, Jeroen, Knippels, Leon M J, Garssen, Johan, Traidl-Hoffmann, Claudia
Published in PloS one (06.07.2015)
Published in PloS one (06.07.2015)
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Journal Article
Selenium Modulates the Allergic Response to Whey Protein in a Mouse Model for Cow's Milk Allergy
Zhao, Xiaoli, Thijssen, Suzan, Chen, Hongbing, Garssen, Johan, Knippels, Leon M J, Hogenkamp, Astrid
Published in Nutrients (22.07.2021)
Published in Nutrients (22.07.2021)
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Journal Article
Limited Lactosylation of Beta-Lactoglobulin from Cow’s Milk Exerts Strong Influence on Antigenicity and Degranulation of Mast Cells
Bosman, Gerlof P, Oliveira, Sergio, Simons, Peter J, Sastre Torano, Javier, Somsen, Govert W, Knippels, Leon M. J, Haselberg, Rob, Pieters, Roland J, Garssen, Johan, Knipping, Karen
Published in Nutrients (01.06.2021)
Published in Nutrients (01.06.2021)
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Journal Article
Dietary, nondigestible oligosaccharides and Bifidobacterium breve M‐16V suppress allergic inflammation in intestine via targeting dendritic cell maturation
Kivit, Sander, Kostadinova, Atanaska I., Kerperien, JoAnn, Morgan, Mary E., Muruzabal, Veronica Ayechu, Hofman, Gerard A., Knippels, Leon M. J., Kraneveld, Aletta D., Garssen, Johan, Willemsen, Linette E. M.
Published in Journal of leukocyte biology (01.07.2017)
Published in Journal of leukocyte biology (01.07.2017)
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Journal Article
Fecal Secretory Immunoglobulin A Is Increased in Healthy Infants Who Receive a Formula with Short-Chain Galacto-Oligosaccharides and Long-Chain Fructo-Oligosaccharides
Scholtens, Petra A.M.J, Alliet, Philippe, Raes, Marc, Alles, Martine S, Kroes, Hilde, Boehm, Guenther, Knippels, Leon M.J, Knol, Jan, Vandenplas, Yvan
Published in The Journal of nutrition (01.06.2008)
Published in The Journal of nutrition (01.06.2008)
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Journal Article
The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies
Wiertsema, Selma P, van Bergenhenegouwen, Jeroen, Garssen, Johan, Knippels, Leon M J
Published in Nutrients (09.03.2021)
Published in Nutrients (09.03.2021)
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Journal Article
The efficacy of oral and subcutaneous antigen‐specific immunotherapy in murine cow's milk‐ and peanut allergy models
Vonk, Marlotte M., Wagenaar, Laura, Pieters, Raymond H. H., Knippels, Leon M. J., Willemsen, Linette E. M., Smit, Joost J., Esch, Betty C. A. M., Garssen, Johan
Published in Clinical and translational allergy (29.09.2017)
Published in Clinical and translational allergy (29.09.2017)
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Journal Article
Non-digestible oligosaccharides scFOS/lcFOS facilitate safe subcutaneous immunotherapy for peanut allergy
Wagenaar, Laura, van Roest, Manon, Kruijssen, Laura J W, Simons, Peter J, Boon, Louis, Vonk, Marlotte M, van Esch, Betty C A M, Knippels, Leon M J, Garssen, Johan, Pieters, Raymond H H, Smit, Joost J
Published in Clinical and molecular allergy CMA (04.04.2019)
Published in Clinical and molecular allergy CMA (04.04.2019)
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Journal Article
In vivo and in vitro evaluation of the residual allergenicity of partially hydrolysed infant formulas
van Esch, Betty C.A.M., Knipping, Karen, Jeurink, Prescilla, van der Heide, Sicco, Dubois, Anthony E.J., Willemsen, Linette E.M., Garssen, Johan, Knippels, Léon M.J.
Published in Toxicology letters (25.03.2011)
Published in Toxicology letters (25.03.2011)
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Journal Article
Supplementation of Mice with Specific Nondigestible Oligosaccharides during Pregnancy or Lactation Leads to Diminished Sensitization and Allergy in the Female Offspring
Hogenkamp, Astrid, Knippels, Leon M J, Garssen, Johan, van Esch, Betty C A M
Published in The Journal of nutrition (01.05.2015)
Published in The Journal of nutrition (01.05.2015)
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Journal Article
Mechanisms underlying immune effects of dietary oligosaccharides
Jeurink, Prescilla V, van Esch, Betty CAM, Rijnierse, Anneke, Garssen, Johan, Knippels, Léon MJ
Published in The American journal of clinical nutrition (01.08.2013)
Published in The American journal of clinical nutrition (01.08.2013)
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Journal Article
Conference Proceeding
Dietary Supplementation throughout Life with Non-Digestible Oligosaccharides and/or n-3 Poly-Unsaturated Fatty Acids in Healthy Mice Modulates the Gut-Immune System-Brain Axis
Szklany, Kirsten, Engen, Phillip A, Naqib, Ankur, Green, Stefan J, Keshavarzian, Ali, Lopez Rincon, Alejandro, Siebrand, Cynthia J, Diks, Mara A P, van de Kaa, Melanie, Garssen, Johan, Knippels, Leon M J, Kraneveld, Aletta D
Published in Nutrients (30.12.2021)
Published in Nutrients (30.12.2021)
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Journal Article
Dietary Supplementation with Nondigestible Oligosaccharides Reduces Allergic Symptoms and Supports Low Dose Oral Immunotherapy in a Peanut Allergy Mouse Model
Wagenaar, Laura, Bol‐Schoenmakers, Marianne, Giustarini, Giulio, Vonk, Marlotte M., Esch, Betty C.A.M., Knippels, Leon M.J., Garssen, Johan, Smit, Joost J., Pieters, Raymond H.H.
Published in Molecular nutrition & food research (01.10.2018)
Published in Molecular nutrition & food research (01.10.2018)
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Journal Article
Selenium-Enriched Soy Protein Has Antioxidant Potential via Modulation of the NRF2-HO1 Signaling Pathway
Zhao, Xiaoli, Gao, Jinyan, Hogenkamp, Astrid, Knippels, Leon M. J., Garssen, Johan, Bai, Jing, Yang, Anshu, Wu, Yong, Chen, Hongbing
Published in Foods (22.10.2021)
Published in Foods (22.10.2021)
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Journal Article
Exploring Immune Development in Infants With Moderate to Severe Atopic Dermatitis
Hulshof, Lies, Overbeek, Saskia A, Wyllie, Anne L, Chu, Mei Ling J N, Bogaert, Debby, de Jager, Wilco, Knippels, Leon M J, Sanders, Elisabeth A M, van Aalderen, Wim M C, Garssen, Johan, Van't Land, Belinda, Sprikkelman, Aline B
Published in Frontiers in immunology (29.03.2018)
Published in Frontiers in immunology (29.03.2018)
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Journal Article
Intestinal Epithelium-Derived Galectin-9 Is Involved in the Immunomodulating Effects of Nondigestible Oligosaccharides
de Kivit, Sander, Kraneveld, Aletta D., Knippels, Leon M.J., van Kooyk, Yvette, Garssen, Johan, Willemsen, Linette E.M.
Published in Journal of innate immunity (01.01.2013)
Published in Journal of innate immunity (01.01.2013)
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Journal Article
Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain
Bloem, Karien, Vuist, Ilona M, van der Plas, Arend-Jan, Knippels, Léon M J, Garssen, Johan, García-Vallejo, Juan J, van Vliet, Sandra J, van Kooyk, Yvette
Published in PloS one (11.06.2013)
Published in PloS one (11.06.2013)
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Journal Article
A network-based approach for identifying suitable biomarkers for oral immunotherapy of food allergy
van Bilsen, Jolanda H M, Verschuren, Lars, Wagenaar, Laura, Vonk, Marlotte M, van Esch, Betty C A M, Knippels, Léon M J, Garssen, Johan, Smit, Joost J, Pieters, Raymond H H, van den Broek, Tim J
Published in BMC bioinformatics (23.04.2019)
Published in BMC bioinformatics (23.04.2019)
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Journal Article
Butyrate Enhances Desensitization Induced by Oral Immunotherapy in Cow’s Milk Allergic Mice
van Esch, Betty C. A. M., Knippels, Leon, Pieters, Raymond H. H., Smit, Joost J., Wagenaar, Laura, Diks, Mara A. P., Blokhuis, B. R., Vonk, Marlotte M., Garssen, J.
Published in Mediators of inflammation (01.01.2019)
Published in Mediators of inflammation (01.01.2019)
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