Harnessing whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation
Cabanes-Creus, Marti, Liao, Sophia H. Y., Gale Navarro, Renina, Knight, Maddison, Nazareth, Deborah, Lau, Ngee-Soon, Ly, Mark, Zhu, Erhua, Roca-Pinilla, Ramon, Bugallo Delgado, Ricardo, Vicente, Ana F., Baltazar, Grober, Westhaus, Adrian, Merjane, Jessica, Crawford, Michael, McCaughan, Geoffrey W., Unzu, Carmen, González-Aseguinolaza, Gloria, Alexander, Ian E., Pulitano, Carlo, Lisowski, Leszek
Published in Nature communications (14.03.2024)
Published in Nature communications (14.03.2024)
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AAV capsid bioengineering in primary human retina models
Westhaus, Adrian, Eamegdool, Steven S., Fernando, Milan, Fuller-Carter, Paula, Brunet, Alicia A., Miller, Annie L., Rashwan, Rabab, Knight, Maddison, Daniszewski, Maciej, Lidgerwood, Grace E., Pébay, Alice, Hewitt, Alex, Santilli, Giorgia, Thrasher, Adrian J., Carvalho, Livia S., Gonzalez-Cordero, Anai, Jamieson, Robyn V., Lisowski, Leszek
Published in Scientific reports (11.12.2023)
Published in Scientific reports (11.12.2023)
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Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes
Kok, Cindy Y., Tsurusaki, Shinya, Cabanes-Creus, Marti, Igoor, Sindhu, Rao, Renuka, Skelton, Rhys, Liao, Sophia H.Y., Ginn, Samantha L., Knight, Maddison, Scott, Suzanne, Mietzsch, Mario, Fitzsimmons, Rebecca, Miller, Jessica, Mohamed, Tamer M.A., McKenna, Robert, Chong, James J.H., Hill, Adam P., Hudson, James E., Alexander, Ian E., Lisowski, Leszek, Kizana, Eddy
Published in Molecular therapy. Methods & clinical development (14.09.2023)
Published in Molecular therapy. Methods & clinical development (14.09.2023)
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Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution
Cabanes-Creus, Marti, Navarro, Renina Gale, Liao, Sophia H.Y., Scott, Suzanne, Carlessi, Rodrigo, Roca-Pinilla, Ramon, Knight, Maddison, Baltazar, Grober, Zhu, Erhua, Jones, Matthew, Denisenko, Elena, Forrest, Alistair R.R., Alexander, Ian E., Tirnitz-Parker, Janina E.E., Lisowski, Leszek
Published in Molecular therapy. Methods & clinical development (09.03.2023)
Published in Molecular therapy. Methods & clinical development (09.03.2023)
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High-Throughput In Vitro , Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction
Westhaus, Adrian, Cabanes-Creus, Marti, Rybicki, Arkadiusz, Baltazar, Grober, Navarro, Renina Gale, Zhu, Erhua, Drouyer, Matthieu, Knight, Maddison, Albu, Razvan F, Ng, Boaz H, Kalajdzic, Predrag, Kwiatek, Magdalena, Hsu, Kenneth, Santilli, Giorgia, Gold, Wendy, Kramer, Belinda, Gonzalez-Cordero, Anai, Thrasher, Adrian J, Alexander, Ian E, Lisowski, Leszek
Published in Human gene therapy (01.05.2020)
Published in Human gene therapy (01.05.2020)
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Development of CNS tropic AAV1-like variants with reduced liver-targeting following systemic administration in mice
Drouyer, Matthieu, Merjane, Jessica, Nazareth, Deborah, Knight, Maddison, Scott, Suzanne, Liao, Sophia H.Y., Ginn, Samantha L., Zhu, Erhua, Alexander, Ian E., Lisowski, Leszek
Published in Molecular therapy (06.03.2024)
Published in Molecular therapy (06.03.2024)
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Backbone 1H, 13C and 15N resonance assignments of the OB domain of the single stranded DNA-binding protein hSSB2 (NABP1/OBFC2A) and chemical shift mapping of the DNA-binding interface
Kariawasam, Ruvini, Knight, Maddison, Gamsjaeger, Roland, Cubeddu, Liza
Published in Biomolecular NMR assignments (01.04.2018)
Published in Biomolecular NMR assignments (01.04.2018)
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Journal Article
Backbone 1 H, 13 C and 15 N resonance assignments of the OB domain of the single stranded DNA-binding protein hSSB2 (NABP1/OBFC2A) and chemical shift mapping of the DNA-binding interface
Kariawasam, Ruvini, Knight, Maddison, Gamsjaeger, Roland, Cubeddu, Liza
Published in Biomolecular NMR assignments (01.04.2018)
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Published in Biomolecular NMR assignments (01.04.2018)
Journal Article
AAV capsid bioengineering in primary human retina
Westhaus, Adrian, Eamegdool, Steven S, Milan, Fernando, Fuller-Carter, Paula, Brunet, Alicia A, Rashwan, Rabab, Knight, Maddison, Daniszewski, Maciej, Lidgerwood, Grace E, Pébay, Alice, Hewitt, Alex, Santilli, Giorgia, Thrasher, Adrian J, Carvalho, Livia S, Gonzalez-Cordero, Anai, Jamieson, Robyn V, Lisowski, Leszek
Published in Research Square (Preprints) (12.09.2023)
Published in Research Square (Preprints) (12.09.2023)
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