A role for PPARα in the control of SREBP activity and lipid synthesis in the liver
Knight, Brian L., Hebbachi, Abdel, Hauton, David, Brown, Anna-Marie, Wiggins, David, Patel, Dilip D., Gibbons, Geoffrey F.
Published in Biochemical journal (15.07.2005)
Published in Biochemical journal (15.07.2005)
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Journal Article
Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin
Sugden, Mary C, Bulmer, Karen, Gibbons, Geoffrey F, Knight, Brian L, Holness, Mark J
Published in Biochemical journal (01.06.2002)
Published in Biochemical journal (01.06.2002)
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Journal Article
Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice
Patel, D D, Knight, B L, Wiggins, D, Humphreys, S M, Gibbons, G F
Published in Journal of lipid research (01.03.2001)
Published in Journal of lipid research (01.03.2001)
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Journal Article
Treatment of aggressive testicular tumors in four dogs
Dhaliwal, R.S, Kitchell, B.E, Knight, B.L, Schmidt, B.R
Published in The Journal of the American Animal Hospital Association (01.07.1999)
Published in The Journal of the American Animal Hospital Association (01.07.1999)
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Journal Article
Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice
Knight, Brian L., Patel, Dilip D., Humphreys, Sandy M., Wiggins, David, Gibbons, Geoffrey F.
Published in Journal of lipid research (01.11.2003)
Published in Journal of lipid research (01.11.2003)
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Journal Article
Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations
Hamadeh, Hisham K, Knight, Brian L, Haugen, Astrid C, Sieber, Stella, Amin, Rupesh P, Bushel, Pierre R, Stoll, Raymond, Blanchard, Kerry, Jayadev, Supriya, Tennant, Raymond W, Cunningham, Michael L, Afshari, Cynthia A, Paules, Richard S
Published in Toxicologic pathology (01.07.2002)
Published in Toxicologic pathology (01.07.2002)
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Journal Article
The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene
Patel, D D, Knight, B L, Soutar, A K, Gibbons, G F, Wade, D P
Published in Biochemical journal (01.11.2000)
Published in Biochemical journal (01.11.2000)
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Journal Article
Characterization of the Rodent Genes for Arylacetamide Deacetylase, a Putative Microsomal Lipase, and Evidence for Transcriptional Regulation
Trickett, J I, Patel, D D, Knight, B L, Saggerson, E D, Gibbons, G F, Pease, R J
Published in The Journal of biological chemistry (26.10.2001)
Published in The Journal of biological chemistry (26.10.2001)
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Journal Article
Characterization of two new point mutations in the low density lipoprotein receptor genes of an English patient with homozygous familial hypercholesterolemia
Webb, JC, Sun, XM, Patel, DD, McCarthy, SN, Knight, BL, Soutar, AK
Published in Journal of lipid research (01.05.1992)
Published in Journal of lipid research (01.05.1992)
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Journal Article
Deficiency of PPARα disturbs the response of lipogenic flux and of lipogenic and cholesterogenic gene expression to dietary cholesterol in mouse white adipose tissue
Islam, K.K., Knight, B.L., Frayn, K.N., Patel, D.D., Gibbons, G.F.
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.06.2005)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.06.2005)
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Journal Article
Determinants of Variable Response to Statin Treatment in Patients With Refractory Familial Hypercholesterolemia
O’Neill, Frans H, Patel, Dilip D, Knight, Brian L, Neuwirth, Clare K.Y, Bourbon, Mafalda, Soutar, Anne K, Taylor, Graham W, Thompson, Gilbert R, Naoumova, Rossitza P
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2001)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2001)
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Journal Article
Influence of genotype at the low density lipoprotein (LDL) receptor gene locus on the clinical phenotype and response to lipid-lowering drug therapy in heterozygous familial hypercholesterolaemia
Sun, Xi-Ming, Patel, Dilip D., Knight, Brian L., Soutar, Anne K.
Published in Atherosclerosis (1998)
Published in Atherosclerosis (1998)
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Journal Article
Variation in lipoprotein(a) concentration associated with different apolipoprotein(a) alleles
PEROMBELON, Y. F. N, SOUTAR, A. K, KNIGHT, B. L
Published in The Journal of clinical investigation (01.04.1994)
Published in The Journal of clinical investigation (01.04.1994)
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Journal Article
C/T Polymorphism in the 5' Untranslated Region of the Apolipoprotein(a) Gene Introduces an Upstream ATG and Reduces In Vitro Translation
Zysow, Bernice R, Lindahl, Gisela E, Wade, David P, Knight, Brian L, Lawn, Richard M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.1995)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.1995)
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