Evaluation of a TGN1412 analogue using in vitro assays and two immune humanized mouse models
Yan, Hangyi, Bhagwat, Bhagyashree, Sanden, David, Willingham, Aarron, Tan, Alick, Knapton, Alan D., Weaver, James L., Howard, Kristina E.
Published in Toxicology and applied pharmacology (01.06.2019)
Published in Toxicology and applied pharmacology (01.06.2019)
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Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions
Weaver, James L, Tobin, Grainne A, Ingle, Taylor, Bancos, Simona, Stevens, David, Rouse, Rodney, Howard, Kristina E, Goodwin, David, Knapton, Alan, Li, Xiaohong, Shea, Katherine, Stewart, Sharron, Xu, Lin, Goering, Peter L, Zhang, Qin, Howard, Paul C, Collins, Jessie, Khan, Saeed, Sung, Kidon, Tyner, Katherine M
Published in Particle and fibre toxicology (17.07.2017)
Published in Particle and fibre toxicology (17.07.2017)
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A multifaceted evaluation of imatinib-induced cardiotoxicity in the rat
Herman, Eugene H, Knapton, Alan, Rosen, Elliot, Thompson, Karol, Rosenzweig, Barry, Estis, Joel, Agee, Sara, Lu, Quynh-Anh, Todd, John A, Lipshultz, Steven, Hasinoff, Brian, Zhang, Jun
Published in Toxicologic pathology (01.12.2011)
Published in Toxicologic pathology (01.12.2011)
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Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats
Thompson, Karol L, Rosenzweig, Barry A, Zhang, Jun, Knapton, Alan D, Honchel, Ronald, Lipshultz, Steven E, Retief, Jacques, Sistare, Frank D, Herman, Eugene H
Published in Cancer chemotherapy and pharmacology (01.07.2010)
Published in Cancer chemotherapy and pharmacology (01.07.2010)
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The iron chelator Dp44mT inhibits the proliferation of cancer cells but fails to protect from doxorubicin-induced cardiotoxicity in spontaneously hypertensive rats
Rao, V. Ashutosh, Zhang, Jun, Klein, Sarah R., Espandiari, Parvaneh, Knapton, Alan, Dickey, Jennifer S., Herman, Eugene, Shacter, Emily B.
Published in Cancer chemotherapy and pharmacology (01.11.2011)
Published in Cancer chemotherapy and pharmacology (01.11.2011)
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The Utility of a Rodent Model in Detecting Pediatric Drug-Induced Nephrotoxicity
Espandiari, Parvaneh, Zhang, Jun, Rosenzweig, Barry A., Vaidya, Vishal S., Sun, Jinchun, Schnackenberg, Laura, Herman, Eugene H., Knapton, Alan, Bonventre, Joseph V., Beger, Richard D., Thompson, Karol L., Hanig, Joseph
Published in Toxicological sciences (01.10.2007)
Published in Toxicological sciences (01.10.2007)
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Journal Article
The utility of serum biomarkers to detect myocardial alterations induced by Imatinib in rats
Herman, Eugene, Knapton, Alan, Zhang, Jun, Estis, Joel, Todd, John, Lipshultz, Steven
Published in Pharmacology research & perspectives (01.02.2014)
Published in Pharmacology research & perspectives (01.02.2014)
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Journal Article
Toxicoproteomics: serum proteomic pattern diagnostics for early detection of drug induced cardiac toxicities and cardioprotection
Petricoin, Emanuel F, Rajapaske, Vinodh, Herman, Eugene H, Arekani, Ali M, Ross, Sally, Johann, Donald, Knapton, Alan, Zhang, J, Hitt, Ben A, Conrads, Thomas P, Veenstra, Timothy D, Liotta, Lance A, Sistare, Frank D
Published in Toxicologic pathology (2004)
Published in Toxicologic pathology (2004)
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Mechanisms and biomarkers of cardiovascular injury induced by phosphodiesterase inhibitor III SK&F 95654 in the spontaneously hypertensive rat
Zhang, Jun, Herman, Eugene H, Robertson, Donald G, Reily, Michael D, Knapton, Alan, Ratajczak, Helen V, Rifai, Nader, Honchel, Ronald, Blanchard, Kerry T, Stoll, Raymond E, Sistare, Frank D
Published in Toxicologic pathology (2006)
Published in Toxicologic pathology (2006)
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Micronucleated erythrocyte frequency in peripheral blood of B6C3F1 mice from short-term, prechronic, and chronic studies of the NTP carcinogenesis bioassay program
Witt, Kristine L., Knapton, Alan, Wehr, Carol M., Hook, Graham J., Mirsalis, Jon, Shelby, Michael D., MacGregor, James T.
Published in Environmental and molecular mutagenesis (2000)
Published in Environmental and molecular mutagenesis (2000)
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Journal Article
SK&F 95654-induced acute cardiovascular toxicity in Sprague-Dawley rats--histopathologic, electron microscopic, and immunohistochemical studies
Zhang, Jun, Herman, Eugene H, Knapton, Alan, Chadwick, Douglas P, Whitehurst, Virgil E, Koerner, John E, Papoian, Thomas, Ferrans, Victor J, Sistare, Frank D
Published in Toxicologic pathology (01.01.2002)
Published in Toxicologic pathology (01.01.2002)
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Quantitative analysis of underivatized 17 β-estradiol using a high-throughput LC–MS/MS assay – Application to support a pharmacokinetic study in ovariectomized guinea pigs
Gandhi, Adarsh, Matta, Murali K., Stewart, Sharron, Chockalingam, Ashok, Knapton, Alan, Rouse, Rodney, Wu, Wendy, Patel, Vikram
Published in Journal of pharmaceutical and biomedical analysis (30.01.2020)
Published in Journal of pharmaceutical and biomedical analysis (30.01.2020)
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Journal Article
MicroRNA biomarkers of pancreatic injury in a canine model
Rouse, Rodney, Rosenzweig, Barry, Shea, Katie, Knapton, Alan, Stewart, Sharron, Xu, Lin, Chockalingam, Ashok, Zadrozny, Leah, Thompson, Karol
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.01.2017)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.01.2017)
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Journal Article
Sex-related differences in mast cell activity and doxorubicin toxicity: a study in spontaneously hypertensive rats
Zhang, Jun, Knapton, Alan, Lipshultz, Steven E, Cochran, Thomas R, Hiraragi, Hajime, Herman, Eugene H
Published in Toxicologic pathology (01.02.2014)
Published in Toxicologic pathology (01.02.2014)
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Autophagy in pancreatic acinar cells in caerulein-treated mice: immunolocalization of related proteins and their potential as markers of pancreatitis
Zhang, Leshuai, Zhang, Jun, Shea, Katherine, Xu, Lin, Tobin, Grainne, Knapton, Alan, Sharron, Stewart, Rouse, Rodney
Published in Toxicologic pathology (01.02.2014)
Published in Toxicologic pathology (01.02.2014)
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Isoproterenol-induced cardiotoxicity in sprague-dawley rats: correlation of reversible and irreversible myocardial injury with release of cardiac troponin T and roles of iNOS in myocardial injury
Zhang, Jun, Knapton, Alan, Lipshultz, Steven E, Weaver, James L, Herman, Eugene H
Published in Toxicologic pathology (01.02.2008)
Published in Toxicologic pathology (01.02.2008)
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The influence of age on serum concentrations of cardiac troponin I: results in rats, monkeys, and commercial sera
Herman, Eugene H, Knapton, Alan, Liu, Yongmin, Lipshultz, Steven E, Estis, Joel, Todd, John, Woodward, Ruth A, Cochran, Thomas, Zhang, Jun, Poirier, Miriam C
Published in Toxicologic pathology (01.07.2014)
Published in Toxicologic pathology (01.07.2014)
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Journal Article
The role of eNOS phosphorylation in causing drug-induced vascular injury
Tobin, Grainne A McMahon, Zhang, Jun, Goodwin, David, Stewart, Sharron, Xu, Lin, Knapton, Alan, González, Carlos, Bancos, Simona, Zhang, Leshuai, Lawton, Michael P, Enerson, Bradley E, Weaver, James L
Published in Toxicologic pathology (01.06.2014)
Published in Toxicologic pathology (01.06.2014)
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Comparison of the diagnostic accuracy of di-22:6-bis(monoacylglycerol)phosphate and other urinary phospholipids for drug-induced phospholipidosis or tissue injury in the rat
Thompson, Karol L, Haskins, Kylie, Rosenzweig, Barry A, Stewart, Sharron, Zhang, Jun, Peters, David, Knapton, Alan, Rouse, Rodney, Mans, Daniel, Colatsky, Thomas
Published in International journal of toxicology (01.01.2012)
Published in International journal of toxicology (01.01.2012)
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