Mice with high FGF21 serum levels had a reduced preference for morphine and an attenuated development of acute antinociceptive tolerance and physical dependence
Dorval, Louben, Knapp, Brian I., Majekodunmi, Olufolake A., Eliseeva, Sophia, Bidlack, Jean M.
Published in Neuropharmacology (01.01.2022)
Published in Neuropharmacology (01.01.2022)
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Journal Article
In Vitro Pharmacological Characterization of Buprenorphine, Samidorphan, and Combinations Being Developed as an Adjunctive Treatment of Major Depressive Disorder
Bidlack, Jean M, Knapp, Brian I, Deaver, Daniel R, Plotnikava, Margarita, Arnelle, Derrick, Wonsey, Angela M, Fern Toh, May, Pin, Sokhom S, Namchuk, Mark N
Published in The Journal of pharmacology and experimental therapeutics (01.11.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2018)
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Journal Article
Antidepressant-like effects of 3-carboxamido seco-nalmefene (3CS-nalmefene), a novel opioid receptor modulator, in a rat IFN-α-induced depression model
Callaghan, Charlotte K., Rouine, Jennifer, Dean, Reginald L., Knapp, Brian I., Bidlack, Jean M., Deaver, Daniel R., O'Mara, Shane M.
Published in Brain, behavior, and immunity (01.01.2018)
Published in Brain, behavior, and immunity (01.01.2018)
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Journal Article
Structural Requirements for CNS Active Opioid Glycopeptides
Lefever, Mark, Li, Yingxue, Anglin, Bobbi, Muthu, Dhanasekaran, Giuvelis, Denise, Lowery, John J, Knapp, Brian I, Bidlack, Jean M, Bilsky, Edward J, Polt, Robin
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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Journal Article
Can Amphipathic Helices Influence the CNS Antinociceptive Activity of Glycopeptides Related to β‑Endorphin?
Li, Yingxue, St. Louis, Lindsay, Knapp, Brian I, Muthu, Dhanasekaran, Anglin, Bobbi, Giuvelis, Denise, Bidlack, Jean M, Bilsky, Edward J, Polt, Robin
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
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Journal Article
Synthesis and Pharmacological Evaluation of Aminothiazolomorphinans at the Mu and Kappa Opioid Receptors
Provencher, Brian A, Sromek, Anna W, Li, Wei, Russell, Shayla, Chartoff, Elena, Knapp, Brian I, Bidlack, Jean M, Neumeyer, John L
Published in Journal of medicinal chemistry (14.11.2013)
Published in Journal of medicinal chemistry (14.11.2013)
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Journal Article
Aminothiazolomorphinans with Mixed κ and μ Opioid Activity
Zhang, Tangzhi, Yan, Zhaohua, Sromek, Anna, Knapp, Brian I, Scrimale, Thomas, Bidlack, Jean M, Neumeyer, John L
Published in Journal of medicinal chemistry (24.03.2011)
Published in Journal of medicinal chemistry (24.03.2011)
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Journal Article
Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling
Ding, Xinxin, Hough, Lindsay B, Conroy, Jennie L, Fang, Cheng, Gu, Jun, Zeitlin, Scott O, Yang, Weizhu, Yang, Jun, VanAlstine, Melissa A, Nalwalk, Julia W, Albrecht, Phillip J, Mazurkiewicz, Joseph E, Snyder-Keller, Abigail, Shan, Zhixing, Zhang, Shao-Zhong, Wentland, Mark P, Behr, Melissa, Knapp, Brian I, Bidlack, Jean M, Zuiderveld, Obbe P, Leurs, Rob
Published in Nature neuroscience (01.03.2010)
Published in Nature neuroscience (01.03.2010)
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Journal Article
Synthesis, Binding Affinity, and Functional in Vitro Activity of 3-Benzylaminomorphinan and 3-Benzylaminomorphine Ligands at Opioid Receptors
Neumeyer, John L, Zhang, Bin, Zhang, Tangzhi, Sromek, Anna W, Knapp, Brian I, Cohen, Dana J, Bidlack, Jean M
Published in Journal of medicinal chemistry (26.04.2012)
Published in Journal of medicinal chemistry (26.04.2012)
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Journal Article
Preliminary Pharmacological Evaluation of Enantiomeric Morphinans
Sromek, Anna W, Provencher, Brian A, Russell, Shayla, Chartoff, Elena, Knapp, Brian I, Bidlack, Jean M, Neumeyer, John L
Published in ACS chemical neuroscience (19.02.2014)
Published in ACS chemical neuroscience (19.02.2014)
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Journal Article
Univalent and Bivalent Ligands of Butorphan: Characteristics of the Linking Chain Determine the Affinity and Potency of Such Opioid Ligands
Decker, Michael, Fulton, Brian S, Zhang, Bin, Knapp, Brian I, Bidlack, Jean M, Neumeyer, John L
Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Journal Article
Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors
VanAlstine, Melissa A., Wentland, Mark P., Alvarez, Juan, Cao, Qing, Cohen, Dana J., Knapp, Brian I., Bidlack, Jean M.
Published in Bioorganic & medicinal chemistry letters (01.04.2013)
Published in Bioorganic & medicinal chemistry letters (01.04.2013)
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Journal Article
Phase Structures and Self-assembled Helical Suprastructures via Hydrogen Bonding in a Series of Achiral 4-Biphenyl Carboxylic Acid Compounds
Jeong, Kwang-Un, Jin, Shi, Ge, Jason J, Knapp, Brian S, Graham, Matthew J, Ruan, Jrjeng, Guo, Mingming, Xiong, Huiming, Harris, Frank W, Cheng, Stephen Z. D
Published in Chemistry of materials (31.05.2005)
Published in Chemistry of materials (31.05.2005)
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Journal Article
Synthesis and Preliminary In vitro Investigation of Bivalent Ligands Containing Homo- and Heterodimeric Pharmacophores at μ, δ, and κ Opioid Receptors
Peng, Xuemei, Knapp, Brian I, Bidlack, Jean M, Neumeyer, John L
Published in Journal of medicinal chemistry (12.01.2006)
Published in Journal of medicinal chemistry (12.01.2006)
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