Tibolone: a steroid with a tissue-specific mode of action
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Journal Article
Conference Proceeding
Selective Tissue Distribution of Tibolone Metabolites in Mature Ovariectomized Female Cynomolgus Monkeys after Multiple Doses of Tibolone
VERHEUL, H. A. M, VAN LERSEL, M. L. P. S, DELBRESSINE, L. P. C, KLOOSTERBOER, H. J
Published in Drug metabolism and disposition (01.07.2007)
Published in Drug metabolism and disposition (01.07.2007)
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Journal Article
Pros and cons of existing treatment modalities in osteoporosis: a comparison between tibolone, SERMs and estrogen (±progestogen) treatments
Kloosterboer, H.J, Ederveen, A.G.H
Published in Journal of steroid biochemistry and molecular biology (01.12.2002)
Published in Journal of steroid biochemistry and molecular biology (01.12.2002)
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Journal Article
Conference Proceeding
Metabolism of exogenous sex steroids and effect on brain functions with a focus on tibolone
Verheul, H.A.M., Kloosterboer, H.J.
Published in Journal of steroid biochemistry and molecular biology (01.12.2006)
Published in Journal of steroid biochemistry and molecular biology (01.12.2006)
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Journal Article
Conference Proceeding
Tibolone Rapidly Attenuates the GABAB Response in Hypothalamic Neurones
Qiu, J., Bosch, M. A., Rønnekleiv, O. K., Kloosterboer, H. J., Kelly, M. J.
Published in Journal of neuroendocrinology (01.12.2008)
Published in Journal of neuroendocrinology (01.12.2008)
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Journal Article
Phosphodiesterase 3 inhibitors suppress oocyte maturation and consequent pregnancy without affecting ovulation and cyclicity in rodents
Wiersma, A, Hirsch, B, Tsafriri, A, Hanssen, R G, Van de Kant, M, Kloosterboer, H J, Conti, M, Hsueh, A J
Published in The Journal of clinical investigation (01.08.1998)
Published in The Journal of clinical investigation (01.08.1998)
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Journal Article
Tibolone Exerts Its Protective Effect on Trabecular Bone Loss Through the Estrogen Receptor
Ederveen, A. G. H., Kloosterboer, H. J.
Published in Journal of bone and mineral research (01.09.2001)
Published in Journal of bone and mineral research (01.09.2001)
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Journal Article
Pharmacokinetic Parameters of Tibolone and Metabolites in Plasma, Urine, Feces, and Bile from Ovariectomized Cynomolgus Monkeys after a Single Dose or Multiple Doses of Tibolone
VERHEUL, H. A. M, TIMMER, C. J, VAN LERSEL, M. L. P. S, DELBRESSINE, L. P. C, KLOOSTERBOER, H. J
Published in Drug metabolism and disposition (01.07.2007)
Published in Drug metabolism and disposition (01.07.2007)
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Journal Article
Development and Characterization of an In Vitro Ovulation Model Using Mouse Ovarian Follicles
ROSE, U. M, HANSSEN, R. G. J. M, KLOOSTERBOER, H. J
Published in Biology of reproduction (01.08.1999)
Published in Biology of reproduction (01.08.1999)
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Journal Article
Molecular Portrait of the Progestagenic and Estrogenic Actions of Tibolone: Behavior of Cellular Networks in Response to Tibolone
Hanifi-Moghaddam, P, Gielen, S. C. J. P, Kloosterboer, H. J, De Gooyer, M. E, Sijbers, A. M, van Gool, A. J, Smid, M, Moorhouse, M, van Wijk, F. H, Burger, C. W, Blok, L. J
Published in The journal of clinical endocrinology and metabolism (01.02.2005)
Published in The journal of clinical endocrinology and metabolism (01.02.2005)
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Journal Article
Progestagenic Effects of Tibolone on Human Endometrial Cancer Cells
Blok, L. J, De Ruiter, P. E, Kühne, E. C. M, Hanekamp, E. E, Grootegoed, J. A, Smid-Koopman, E, Gielen, S. C. J. P, De Gooyer, M. E, Kloosterboer, H. J, Burger, C. W
Published in The journal of clinical endocrinology and metabolism (01.05.2003)
Published in The journal of clinical endocrinology and metabolism (01.05.2003)
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Journal Article
Effects of stable transfection of human fetal osteoblast cells with estrogen receptor-alpha on regulation of gene expression by tibolone
Maran, A., Shogren, K., Zhang, M., Yaszemski, M.J., Hefferan, T.E., Spelsberg, T.C., Kloosterboer, H.J., Turner, R.T.
Published in Bone (New York, N.Y.) (01.09.2006)
Published in Bone (New York, N.Y.) (01.09.2006)
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Journal Article
Molecular analysis of human endometrium : short-term tibolone signaling differs significantly from estrogen and estrogen + progestagen signaling
HANIFI-MOGHADDAM, P, BOERS-SIJMONS, B, BLOK, L. J, KLAASSENS, A. H. A, VAN WIJK, F. H, DEN BAKKER, M. A, OTT, M. C, SHIPLEY, G. L, VERHEUL, H. A. M, KLOOSTERBOER, H. J, BURGER, C. W
Published in Journal of molecular medicine (Berlin, Germany) (01.05.2007)
Published in Journal of molecular medicine (Berlin, Germany) (01.05.2007)
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Journal Article
Historical milestones in the development of tibolone (Livial®)
Kloosterboer, H. J.
Published in Climacteric : the journal of the International Menopause Society (01.12.2011)
Published in Climacteric : the journal of the International Menopause Society (01.12.2011)
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Journal Article
In vitro effects of tibolone and its metabolites on human vascular coronary cells
Seeger, H, Kloosterboer, H.J, Studen, M, Wallwiener, D, Mueck, A.O
Published in Maturitas (20.09.2007)
Published in Maturitas (20.09.2007)
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Journal Article
Effect of 16 Months of Treatment with Tibolone on Bone Mass, Turnover, and Biomechanical Quality in Mature Ovariectomized Rats
Ederveen, A. G. H., Spanjers, C. P. M., Quaijtaal, J. H. M., Kloosterboer, H. J.
Published in Journal of bone and mineral research (01.09.2001)
Published in Journal of bone and mineral research (01.09.2001)
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Journal Article