Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity
Coomans, Claudia P, van den Berg, Sjoerd A A, Houben, Thijs, van Klinken, Jan-Bert, van den Berg, Rosa, Pronk, Amanda C M, Havekes, Louis M, Romijn, Johannes A, van Dijk, Ko Willems, Biermasz, Nienke R, Meijer, Johanna H
Published in The FASEB journal (01.04.2013)
Published in The FASEB journal (01.04.2013)
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The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South Asian and Europid men
Nahon, Kimberly J., Janssen, Laura G. M., Sardjoe Mishre, Aashley S. D., Bilsen, Manu P., Eijk, Jari A., Botani, Kani, Overduin, Lisanne A., Ruiz, Jonatan R., Burakiewicz, Jedrzej, Dzyubachyk, Oleh, Webb, Andrew G., Kan, Hermien E., Berbée, Jimmy F. P., Klinken, Jan‐Bert, Dijk, Ko Willems, Weeghel, Michel, Vaz, Frédéric M., Coskun, Tamer, Jazet, Ingrid M., Kooijman, Sander, Martinez‐Tellez, Borja, Boon, Mariëtte R., Rensen, Patrick C. N.
Published in Diabetes, obesity & metabolism (01.11.2020)
Published in Diabetes, obesity & metabolism (01.11.2020)
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Alterations in ether lipid metabolism and the consequences for the mouse lipidome
Lackner, Katharina, Sailer, Sabrina, van Klinken, Jan-Bert, Wever, Eric, Pras-Raves, Mia L., Dane, Adrie D., Honsho, Masanori, Abe, Yuichi, Keller, Markus A., Golderer, Georg, Werner-Felmayer, Gabriele, Fujiki, Yukio, Vaz, Frédéric M., Werner, Ernst R., Watschinger, Katrin
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.04.2023)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.04.2023)
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Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake
van den Berg, Sjoerd A A, Heemskerk, Mattijs M, Geerling, Janine J, van Klinken, Jan-Bert, Schaap, Frank G, Bijland, Silvia, Berbée, Jimmy F P, van Harmelen, Vanessa J A, Pronk, Amanda C M, Schreurs, Marijke, Havekes, Louis M, Rensen, Patrick C N, van Dijk, Ko Willems
Published in The FASEB journal (01.08.2013)
Published in The FASEB journal (01.08.2013)
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A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes
Liu, Jun, van Klinken, Jan Bert, Semiz, Sabina, van Dijk, Ko Willems, Verhoeven, Aswin, Hankemeier, Thomas, Harms, Amy C, Sijbrands, Eric, Sheehan, Nuala A, van Duijn, Cornelia M, Demirkan, Ayşe
Published in Diabetes (New York, N.Y.) (01.11.2017)
Published in Diabetes (New York, N.Y.) (01.11.2017)
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Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease
Lee, Richard G, Balasubramaniam, Shanti, Stentenbach, Maike, Kralj, Tom, McCubbin, Tim, Padman, Benjamin, Smith, Janine, Riley, Lisa G, Priyadarshi, Archana, Peng, Liuyu, Nuske, Madison R, Webster, Richard, Peacock, Ken, Roberts, Philip, Stark, Zornitza, Lemire, Gabrielle, Ito, Yoko A, Boycott, Kym M, Geraghty, Michael T, van Klinken, Jan Bert, Ferdinandusse, Sacha, Zhou, Ying, Walsh, Rebecca, Marcellin, Esteban, Thorburn, David R, Rosciolli, Tony, Fletcher, Janice, Rackham, Oliver, Vaz, Frédéric M, Reid, Gavin E, Filipovska, Aleksandra
Published in Human molecular genetics (28.10.2022)
Published in Human molecular genetics (28.10.2022)
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Journal Article
Tracer‐based lipidomics enables the discovery of disease‐specific candidate biomarkers in mitochondrial β‐oxidation disorders
Schwantje, Marit, Mosegaard, Signe, Knottnerus, Suzan J. G., Klinken, Jan Bert, Wanders, Ronald J., Lenthe, Henk, Hermans, Jill, IJlst, Lodewijk, Denis, Simone W., Jaspers, Yorrick R. J., Fuchs, Sabine A., Houtkooper, Riekelt H., Ferdinandusse, Sacha, Vaz, Frédéric M.
Published in The FASEB journal (29.02.2024)
Published in The FASEB journal (29.02.2024)
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A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
Deelen, Joris, Kettunen, Johannes, Fischer, Krista, van der Spek, Ashley, Trompet, Stella, Kastenmüller, Gabi, Boyd, Andy, Zierer, Jonas, van den Akker, Erik B, Ala-Korpela, Mika, Amin, Najaf, Demirkan, Ayse, Ghanbari, Mohsen, van Heemst, Diana, Ikram, M Arfan, van Klinken, Jan Bert, Mooijaart, Simon P, Peters, Annette, Salomaa, Veikko, Sattar, Naveed, Spector, Tim D, Tiemeier, Henning, Verhoeven, Aswin, Waldenberger, Melanie, Würtz, Peter, Davey Smith, George, Metspalu, Andres, Perola, Markus, Menni, Cristina, Geleijnse, Johanna M, Drenos, Fotios, Beekman, Marian, Jukema, J Wouter, van Duijn, Cornelia M, Slagboom, P Eline
Published in Nature communications (20.08.2019)
Published in Nature communications (20.08.2019)
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Hepatic triglyceride content is intricately associated with numerous metabolites and biochemical pathways
Faquih, Tariq O., Klinken, Jan Bert, Li‐Gao, Ruifang, Noordam, Raymond, Heemst, Diana, Boone, Sebastiaan, Sheridan, Patricia A., Michelotti, Gregory, Lamb, Hildo, Mutsert, Renée, Rosendaal, Frits R., Hylckama Vlieg, Astrid, Dijk, Ko Willems, Mook‐Kanamori, Dennis O.
Published in Liver international (01.07.2023)
Published in Liver international (01.07.2023)
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Adverse generational changes in obesity development converge at midlife without increased cardiometabolic risk
Ibi, Dorina, Rietman, M. Liset, Picavet, H. S. J., Klinken, Jan Bert, Dijk, Ko Willems, Dollé, Martijn E. T., Verschuren, W.M. Monique
Published in Obesity (Silver Spring, Md.) (01.11.2021)
Published in Obesity (Silver Spring, Md.) (01.11.2021)
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Reduced Feed Intake, Rather than Increased Energy Losses, Explains Variation in Growth Rates of Normal-Birth-Weight Piglets
van Erp, Rik J J, van Hees, Hubert M J, Zijlstra, Ruurd T, van Kempen, Theo A T G, van Klinken, Jan Bert, Gerrits, Walter J J
Published in The Journal of nutrition (01.11.2018)
Published in The Journal of nutrition (01.11.2018)
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CD36 is important for adipocyte recruitment and affects lipolysis
Vroegrijk, Irene O.C.M., Klinken, Jan Bert, Diepen, Janna A., den Berg, Sjoerd A.A., Febbraio, Maria, Steinbusch, Laura K.M., Glatz, Jan F.C., Havekes, Louis M., Voshol, Peter J., Rensen, Patrick C.N., Dijk, Ko Willems, Harmelen, Vanessa
Published in Obesity (Silver Spring, Md.) (01.10.2013)
Published in Obesity (Silver Spring, Md.) (01.10.2013)
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Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry
Jaspers, Yorrick R.J., Meyer, Sven W., Pras-Raves, Mia L., Dijkstra, Inge M.E., Wever, Eric J.M., Dane, Adrie D., van Klinken, Jan-Bert, Salomons, Gajja S., Houtkooper, Riekelt H., Engelen, Marc, Kemp, Stephan, Van Weeghel, Michel, Vaz, Frédéric M.
Published in Journal of lipid research (01.06.2024)
Published in Journal of lipid research (01.06.2024)
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Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation
Held, Ntsiki M, Kuipers, Eline N, van Weeghel, Michel, van Klinken, Jan Bert, Denis, Simone W, Lombès, Marc, Wanders, Ronald J, Vaz, Frédéric M, Rensen, Patrick C N, Verhoeven, Arthur J, Boon, Mariëtte R, Houtkooper, Riekelt H
Published in Scientific reports (22.06.2018)
Published in Scientific reports (22.06.2018)
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Long-term niacin treatment induces insulin resistance and adrenergic responsiveness in adipocytes by adaptive downregulation of phosphodiesterase 3B
Heemskerk, Mattijs M, van den Berg, Sjoerd A A, Pronk, Amanda C M, van Klinken, Jan-Bert, Boon, Mariëtte R, Havekes, Louis M, Rensen, Patrick C N, van Dijk, Ko Willems, van Harmelen, Vanessa
Published in American journal of physiology: endocrinology and metabolism (01.04.2014)
Published in American journal of physiology: endocrinology and metabolism (01.04.2014)
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Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses
Demirkan, Ayşe, Henneman, Peter, Verhoeven, Aswin, Dharuri, Harish, Amin, Najaf, van Klinken, Jan Bert, Karssen, Lennart C, de Vries, Boukje, Meissner, Axel, Göraler, Sibel, van den Maagdenberg, Arn M J M, Deelder, André M, C 't Hoen, Peter A, van Duijn, Cornelia M, van Dijk, Ko Willems
Published in PLoS genetics (01.01.2015)
Published in PLoS genetics (01.01.2015)
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Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue
van Eenige, Robin, In het Panhuis, Wietse, Schönke, Milena, Jouffe, Céline, Devilee, Thomas H., Siebeler, Ricky, Streefland, Trea C.M., Sips, Hetty C.M., Pronk, Amanda C.M., Vorderman, Ruben H.P., Mei, Hailiang, van Klinken, Jan Bert, van Weeghel, Michel, Uhlenhaut, Nina H., Kersten, Sander, Rensen, Patrick C.N., Kooijman, Sander
Published in Molecular metabolism (Germany) (01.06.2022)
Published in Molecular metabolism (Germany) (01.06.2022)
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Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: A two-hit model of hypertrophic cardiomyopathy
Nollet, Edgar E., Algül, Sila, Goebel, Max, Schlossarek, Saskia, van der Wel, Nicole N., Jans, Judith J.M., van de Wiel, Mark A., Knol, Jaco C., Pham, Thang V., Piersma, Sander R., de Goeij-de Haas, Richard, Hermans, Jill, van Klinken, Jan Bert, van Weeghel, Michel, Houtkooper, Riekelt H., Carrier, Lucie, Jimenez, Connie R., Kuster, Diederik W.D., van der Velden, Jolanda
Published in Journal of Molecular and Cellular Cardiology Plus (Online) (01.12.2023)
Published in Journal of Molecular and Cellular Cardiology Plus (Online) (01.12.2023)
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High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57B1/6 mice
VAN DEN BERG, Sjoerd A. A, NABBEN, Miranda, WILLEMS VAN DIJK, Ko, BIJLAND, Silvia, VOSHOL, Peter J, BERT VAN KLINKEN, Jan, HAVEKES, Louis M, ROMIJN, Johannes A, HOEKS, Joris, HESSELINK, Matthijs K, SCHRAUWEN, Patrick
Published in Metabolism, clinical and experimental (01.11.2010)
Published in Metabolism, clinical and experimental (01.11.2010)
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