Thiophene‐Based Ligands for Histological Multiplex Spectral Detection of Distinct Protein Aggregates in Alzheimer's Disease
Lantz, Linda, Shirani, Hamid, Ghetti, Bernardino, Vidal, Ruben, Klingstedt, Therése, Nilsson, K. Peter R.
Published in Chemistry : a European journal (13.04.2023)
Published in Chemistry : a European journal (13.04.2023)
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Synthesis and Characterization of Thiophene‐based Donor–Acceptor–Donor Heptameric Ligands for Spectral Assignment of Polymorphic Amyloid‐β Deposits
Lantz, Linda, Shirani, Hamid, Klingstedt, Therése, Nilsson, K. Peter R.
Published in Chemistry : a European journal (10.06.2020)
Published in Chemistry : a European journal (10.06.2020)
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Distinct Heterocyclic Moieties Govern the Selectivity of Thiophene-Vinylene-Based Ligands towards Aβ or Tau Pathology in Alzheimer's Disease
Bjork, Linnea, Shirani, Hamid, Todarwal, Yogesh, Linares, Mathieu, Vidal, Ruben, Ghetti, Bernardino, Norman, Patrick, Klingstedt, Therese, Nilsson, K. Peter R.
Published in European journal of organic chemistry (02.11.2023)
Published in European journal of organic chemistry (02.11.2023)
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Proteophenes – Amino Acid Functionalized Thiophene‐based Fluorescent Ligands for Visualization of Protein Deposits in Tissue Sections with Alzheimer's Disease Pathology
Björk, Linnea, Bäck, Marcus, Lantz, Linda, Ghetti, Bernardino, Vidal, Ruben, Klingstedt, Therése, Nilsson, K. Peter R.
Published in Chemistry : a European journal (07.11.2022)
Published in Chemistry : a European journal (07.11.2022)
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In vitro metabolism study of ADB-P-5Br-INACA and ADB-4en-P-5Br-INACA using human hepatocytes, liver microsomes, and in-house synthesized references
Rautio, Tobias, Obrist, Robin, Krebs, Lucas, Klingstedt, Therése, Dahlén, Johan, Wu, Xiongyu, Gréen, Henrik
Published in Drug testing and analysis (23.07.2024)
Published in Drug testing and analysis (23.07.2024)
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Synthesis of Thiophene‐Based Optical Ligands That Selectively Detect Tau Pathology in Alzheimer's Disease
Shirani, Hamid, Appelqvist, Hanna, Bäck, Marcus, Klingstedt, Therése, Cairns, Nigel J., Nilsson, K. Peter R.
Published in Chemistry : a European journal (01.12.2017)
Published in Chemistry : a European journal (01.12.2017)
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Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish [beta]-Amyloid or Tau Polymorphic Aggregates
Klingstedt, Therése, Shirani, Hamid, Mahler, Jasmin, Wegenast-Braun, Bettina M, Nystrom, Sofie, Goedert, Michel, Jucker, Mathias, Nilsson, K Peter R
Published in Chemistry : a European journal (15.06.2015)
Published in Chemistry : a European journal (15.06.2015)
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Tau Protein Binding Modes in Alzheimer’s Disease for Cationic Luminescent Ligands
Todarwal, Yogesh, Gustafsson, Camilla, Thi Minh, Nghia Nguyen, Ertzgaard, Ingrid, Klingstedt, Therése, Ghetti, Bernardino, Vidal, Ruben, König, Carolin, Lindgren, Mikael, Nilsson, K. Peter R, Linares, Mathieu, Norman, Patrick
Published in The journal of physical chemistry. B (28.10.2021)
Published in The journal of physical chemistry. B (28.10.2021)
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Novel Pentameric Thiophene Derivatives for in Vitro and in Vivo Optical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses
Åslund, Andreas, Sigurdson, Christina J, Klingstedt, Therése, Grathwohl, Stefan, Bolmont, Tristan, Dickstein, Dara L, Glimsdal, Eirik, Prokop, Stefan, Lindgren, Mikael, Konradsson, Peter, Holtzman, David M, Hof, Patrick R, Heppner, Frank L, Gandy, Samuel, Jucker, Mathias, Aguzzi, Adriano, Hammarström, Per, Nilsson, K. Peter R
Published in ACS chemical biology (21.08.2009)
Published in ACS chemical biology (21.08.2009)
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Host oligodendrogliopathy and α-synuclein strains dictate disease severity in multiple system atrophy
Torre-Muruzabal, Teresa, Van der Perren, Anke, Coens, Audrey, Gelders, Géraldine, Janer, Anna Barber, Camacho-Garcia, Sara, Klingstedt, Therése, Nilsson, Peter, Stefanova, Nadia, Melki, Ronald, Baekelandt, Veerle, Peelaerts, Wouter
Published in Brain (London, England : 1878) (05.01.2023)
Published in Brain (London, England : 1878) (05.01.2023)
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Thiophene-Based Ligands for Specific Assignment of Distinct Aβ Pathologies in Alzheimer's Disease
Klingstedt, Therése, Lantz, Linda, Shirani, Hamid, Ge, Junyue, Hanrieder, Jörg, Vidal, Ruben, Ghetti, Bernardino, Nilsson, K. Peter R.
Published in ACS chemical neuroscience (03.04.2024)
Published in ACS chemical neuroscience (03.04.2024)
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The Structural Basis for Optimal Performance of Oligothiophene-Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates
Klingstedt, Therése, Shirani, Hamid, Åslund, K. O. Andreas, Cairns, Nigel J., Sigurdson, Christina J., Goedert, Michel, Nilsson, K. Peter R.
Published in Chemistry : a European journal (29.07.2013)
Published in Chemistry : a European journal (29.07.2013)
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Synapsin III gene silencing redeems alpha-synuclein transgenic mice from Parkinson's disease-like phenotype
Faustini, Gaia, Longhena, Francesca, Masato, Anna, Bassareo, Valentina, Frau, Roberto, Klingstedt, Therése, Shirani, Hamid, Brembati, Viviana, Parrella, Edoardo, Vezzoli, Marika, Nilsson, K. Peter R., Pizzi, Marina, Spillantini, Maria Grazia, Bubacco, Luigi, Bellucci, Arianna
Published in Molecular therapy (06.04.2022)
Published in Molecular therapy (06.04.2022)
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Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson's disease and multiple system atrophy
Klingstedt, Therése, Ghetti, Bernardino, Holton, Janice L, Ling, Helen, Nilsson, K Peter R, Goedert, Michel
Published in Acta neuropathologica communications (03.12.2019)
Published in Acta neuropathologica communications (03.12.2019)
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Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates
Klingstedt, Therese, Aslund, Andreas, Simon, Rozalyn A., Johansson, Leif B. G., Mason, Jeffrey J., Nystrom, Sofie, Hammarstrom, Per, Nilsson, K. Peter R.
Published in Organic & biomolecular chemistry (21.12.2011)
Published in Organic & biomolecular chemistry (21.12.2011)
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Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates
Klingstedt, Therése, Shirani, Hamid, Mahler , Jasmin, Wegenast-Braun , Bettina M., Nyström, Sofie, Goedert, Michel, Jucker , Mathias, Nilsson, K. Peter R.
Published in Chemistry : a European journal (15.06.2015)
Published in Chemistry : a European journal (15.06.2015)
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