Pre-existing technological core and roots for the CRISPR breakthrough
Magee, Christopher L, Kleyn, Patrick W, Monks, Brendan M, Betz, Ulrich, Basnet, Subarna
Published in PloS one (19.09.2018)
Published in PloS one (19.09.2018)
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Genetic Variation as a Guide to Drug Development
Kleyn, Patrick W., Vesell, Elliot S.
Published in Science (American Association for the Advancement of Science) (18.09.1998)
Published in Science (American Association for the Advancement of Science) (18.09.1998)
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Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment
Lechner, Lara, Opitz, Robert, Silver, Matt J, Krabusch, Philipp M, Prentice, Andrew M, Field, Martha S, Stachelscheid, Harald, Leitão, Elsa, Schröder, Christopher, Fernandez Vallone, Valeria, Horsthemke, Bernhard, Jöckel, Karl-Heinz, Schmidt, Börge, Nöthen, Markus M, Hoffmann, Per, Herms, Stefan, Kleyn, Patrick W, Megges, Matthias, Blume-Peytavi, Ulrike, Weiss, Katja, Mai, Knut, Blankenstein, Oliver, Obermayer, Benedikt, Wiegand, Susanna, Kühnen, Peter
Published in Science translational medicine (19.07.2023)
Published in Science translational medicine (19.07.2023)
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Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort
WILSON, Scott G, ADAM, Gail, SAMBROOK, Philip N, KLEYN, Patrick W, SPECTOR, Tim D, LANGDOWN, Maria, RENELAND, Rikard, BRAUN, Andreas, ANDREW, Toby, SURDULESCU, Gabriela L, NORBERG, Maria, DUDBRIDGE, Frank, REED, Peter W
Published in European journal of human genetics : EJHG (01.03.2006)
Published in European journal of human genetics : EJHG (01.03.2006)
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Identification and functional analysis of novel human melanocortin-4 receptor variants
WEI GU, ZHIMING TU, FRANCO, L. S, BURN, P, YAGALOFF, K. A, NATHAN, J, HEYMSFIELD, S, ALBU, J, PI-SUNYER, F. X, ALLISON, D. B, KLEYN, P. W, KISSEBAH, A, DUPRAT, L, LEE, J, CHIN, W, MARUTI, S, DENG, N, FISHER, S. L
Published in Diabetes (New York, N.Y.) (01.03.1999)
Published in Diabetes (New York, N.Y.) (01.03.1999)
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TULP1 mutation in two extended Dominican kindreds with autosomal recessive Retinitis pigmentosa
Banerjee, Poulabi, Kleyn, Patrick W, Knowles, James A, Lewis, Charles A, Ross, Barbara M, Parano, Enrico, Kovats, Steve G, Lee, John J, Penchaszadeh, Graciela K, Ott, Jürg, Jacobson, Samuel G, Gilliam, T. Conrad
Published in Nature genetics (01.02.1998)
Published in Nature genetics (01.02.1998)
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Limatin (LIMAB1), an Actin-Binding LIM Protein, Maps to Mouse Chromosome 19 and Human Chromosome 10q25, a Region Frequently Deleted in Human Cancers
Kim, Anthony C., Peters, Luanne L., Knoll, Joan H.M., Van Huffel, Christophe, Ciciotte, Steven L., Kleyn, Patrick W., Chishti, Athar H.
Published in Genomics (San Diego, Calif.) (01.12.1997)
Published in Genomics (San Diego, Calif.) (01.12.1997)
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Journal Article
Pre-existing Technological Core and Roots for the CRISPR Breakthrough
Magee, Christopher L, Kleyn, Patrick W, Monks, Brendan M, Betz, Ulrich, Basnet, Subarna
Published in bioRxiv (24.05.2018)
Published in bioRxiv (24.05.2018)
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Paper
Identification and Characterization of the Mouse Obesity Gene tubby: A Member of a Novel Gene Family
Kleyn, Patrick W, Fan, Wei, Kovats, Steve G, Lee, John J, Pulido, Jacqueline C, Wu, Ye, Berkemeier, Lucy R, Misumi, Don J, Holmgren, Lisa, Charlat, Olga, Woolf, Elizabeth A, Tayber, Olga, Brody, Thomas, Shu, Pei, Hawkins, Fiona, Kennedy, Brenda, Baldini, Linda, Ebeling, Chris, Alperin, Geoffrey D, Deeds, Jim, Lakey, Nathan D, Culpepper, Janice, Chen, Hong, Glücksmann-Kuis, M.Alexandra, Carlson, George A, Duyk, Geoffrey M, Moore, Karen J
Published in Cell (19.04.1996)
Published in Cell (19.04.1996)
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Journal Article
Construction of a Yeast Artificial Chromosome Contig Spanning the Spinal Muscular Atrophy Disease Gene Region
Kleyn, Patrick W., Wang, Ching H., Lien, Lyndon L., Vitale, Emilia, Pan, Jie, Ross, Barbara M., Grunn, Adina, Palmer, David A., Warburton, Dorothy, Brzustowicz, Linda M., Kunkel, Louis M., Gilliam, T. Conrad
Published in Proceedings of the National Academy of Sciences - PNAS (15.07.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (15.07.1993)
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Journal Article
Refinement of the Spinal Muscular Atrophy Locus to the Interval between D5S435 and MAP1B
Soares, Vera M., Brzustowicz, Linda M., Kleyn, Patrick W., Knowles, James A., Palmer, David A., Asokan, Susha, Penchaszadeh, Graciela K., Munsat, Theodore L., Gilliam, T.Conrad
Published in Genomics (San Diego, Calif.) (01.02.1993)
Published in Genomics (San Diego, Calif.) (01.02.1993)
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Journal Article
Homozygosity and Physical Mapping of the Autosomal Recessive Retinitis Pigmentosa Locus (RP14) on Chromosome 6p21.3
Banerjee, Poulabi, Lewis, Charles A., Kleyn, Patrick W., Shugart, Yin Y., Ross, Barbara M., Penchaszadeh, Graciela K., Ott, Jurg, Jacobson, Samuel G., Gilliam, T.Conrad, Knowles, James A.
Published in Genomics (San Diego, Calif.) (01.03.1998)
Published in Genomics (San Diego, Calif.) (01.03.1998)
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Journal Article
Isolation of coding sequences and evaluation of candidate genes for spinal muscular atrophy
Wang, Ching H., Kleyn, Patrick W., Xu, Jin, Vitale, Emilia, Carter, Todd A., Ross, Barbara M., Das, Kamna, Soares, Marcelo B., Brzustowicz, Linda M., Kunkel, Louis M., Conrad Gilliam, T.
Published in Pediatric neurology (01.09.1994)
Published in Pediatric neurology (01.09.1994)
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