Targeting IFN activity to both B cells and plasmacytoid dendritic cells induces a robust tolerogenic response and protection against EAE
Cauwels, Anje, Van Lint, Sandra, Rogge, Elke, Verhee, Annick, Van Den Eeckhout, Bram, Pang, Shengru, Prinz, Marco, Kley, Niko, Uzé, Gilles, Tavernier, Jan
Published in Scientific reports (03.11.2021)
Published in Scientific reports (03.11.2021)
Get full text
Journal Article
Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments
Cauwels, Anje, Van Lint, Sandra, Paul, Franciane, Garcin, Geneviève, De Koker, Stefaan, Van Parys, Alexander, Wueest, Thomas, Gerlo, Sarah, Van der Heyden, José, Bordat, Yann, Catteeuw, Dominiek, Rogge, Elke, Verhee, Annick, Vandekerckhove, Bart, Kley, Niko, Uzé, Gilles, Tavernier, Jan
Published in Cancer research (Chicago, Ill.) (15.01.2018)
Published in Cancer research (Chicago, Ill.) (15.01.2018)
Get full text
Journal Article
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state
Van Lint, Sandra, Van Parys, Alexander, Van Den Eeckhout, Bram, Vandamme, Niels, Plaisance, Stephane, Verhee, Annick, Catteeuw, Dominiek, Rogge, Elke, De Geest, Jennifer, Vanderroost, Nele, Roels, Jana, Saeys, Yvan, Uzé, Gilles, Kley, Niko, Cauwels, Anje, Tavernier, Jan
Published in Molecular cancer (29.11.2023)
Published in Molecular cancer (29.11.2023)
Get full text
Journal Article
Safe eradication of large established tumors using neovasculature‐targeted tumor necrosis factor‐based therapies
Huyghe, Leander, Van Parys, Alexander, Cauwels, Anje, Van Lint, Sandra, De Munter, Stijn, Bultinck, Jennyfer, Zabeau, Lennart, Hostens, Jeroen, Goethals, An, Vanderroost, Nele, Verhee, Annick, Uzé, Gilles, Kley, Niko, Peelman, Frank, Vandekerckhove, Bart, Brouckaert, Peter, Tavernier, Jan
Published in EMBO molecular medicine (07.02.2020)
Published in EMBO molecular medicine (07.02.2020)
Get full text
Journal Article
High efficacy of huCD20-targeted AcTaferon in humanized patient derived xenograft models of aggressive B cell lymphoma
Daneels, Willem, Van Parys, Alexander, Huyghe, Leander, Rogge, Elke, De Rouck, Steffi, Christiaen, Ruben, Zabeau, Lennart, Taveirne, Sylvie, Van Dorpe, Jo, Kley, Niko, Cauwels, Anje, Depla, Erik, Tavernier, Jan, Offner, Fritz
Published in Experimental hematology & oncology (03.06.2024)
Published in Experimental hematology & oncology (03.06.2024)
Get full text
Journal Article
1402 A potent, CD8 T cell targeted IL-2 A-Kine with a broad therapeutic window induces antitumor immunity in syngeneic and humanized mouse tumor models
Zabeau, Lennart, Cauwels, Anje, Parys, Alexander Van, Taveirne, Sylvie, Lopes, Jared E, Depla, Erik, Kley, Niko
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
Get full text
Journal Article
Selective IL-1 activity on CD8+ T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication
Van Den Eeckhout, Bram, Huyghe, Leander, Van Lint, Sandra, Burg, Elianne, Plaisance, Stéphane, Peelman, Frank, Cauwels, Anje, Uzé, Gilles, Kley, Niko, Gerlo, Sarah, Tavernier, Jan
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
Get full text
Journal Article
Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant
Van Den Eeckhout, Bram, Van Hoecke, Lien, Burg, Elianne, Van Lint, Sandra, Peelman, Frank, Kley, Niko, Uzé, Gilles, Saelens, Xavier, Tavernier, Jan, Gerlo, Sarah
Published in npj vaccines (23.07.2020)
Published in npj vaccines (23.07.2020)
Get full text
Journal Article
Targeting interferon activity to dendritic cells enables in vivo tolerization and protection against EAE in mice
Cauwels, Anje, Van Lint, Sandra, Catteeuw, Dominiek, Pang, Shengru, Paul, Franciane, Rogge, Elke, Verhee, Annick, Prinz, Marco, Kley, Niko, Uzé, Gilles, Tavernier, Jan
Published in Journal of autoimmunity (01.02.2019)
Published in Journal of autoimmunity (01.02.2019)
Get full text
Journal Article
The use of mammalian two-hybrid technologies for high-throughput drug screening
Lievens, Sam, Caligiuri, Maureen, Kley, Niko, Tavernier, Jan
Published in Methods (San Diego, Calif.) (01.12.2012)
Published in Methods (San Diego, Calif.) (01.12.2012)
Get full text
Journal Article
Specific targeting of IL-1β activity to CD8 + T cells allows for safe use as a vaccine adjuvant
Van Den Eeckhout, Bram, Van Hoecke, Lien, Burg, Elianne, Van Lint, Sandra, Peelman, Frank, Kley, Niko, Uzé, Gilles, Saelens, Xavier, Tavernier, Jan, Gerlo, Sarah
Published in npj vaccines (23.07.2020)
Get full text
Published in npj vaccines (23.07.2020)
Journal Article