Erlotinib in combination with pemetrexed for patients with advanced non-small-cell lung cancer (NSCLC): a phase I dose-finding study
Ranson, M., Reck, M., Anthoney, A., Hanauske, A.-R., Dean, E., Melezinek, I., Klingelschmitt, G., Kletzl, H., Blatter, J., Twelves, C.
Published in Annals of oncology (01.11.2010)
Published in Annals of oncology (01.11.2010)
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First-in-man study with a novel PEGylated recombinant human insulin-like growth factor-I
Kletzl, H, Guenther, A, Hoeflich, A, Hoeflich, C, Frystyk, J, Staack, R.F, Schick, E, Wandel, C, Bleich, N, Metzger, F
Published in Growth hormone & IGF research (01.04.2017)
Published in Growth hormone & IGF research (01.04.2017)
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P232 Bioavailability and bioequivalence of Risdiplam tablets in healthy volunteers
Kletzl, H., Heinig, K., Jaber, B., Lomeli, B., Yeung, W., Young, A., Coleman, H., Morrison, D.
Published in Neuromuscular disorders : NMD (01.10.2023)
Published in Neuromuscular disorders : NMD (01.10.2023)
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P227 MANATEE: GYM329 (RO7204239) in combination with Risdiplam treatment in patients with spinal muscular atrophy (SMA)
Duong, T., Darras, B., Morrow, J., Muntoni, F., Servais, L., Rabbia, M., Gerber, M., Kletzl, H., Gaki, E., Fletcher, S., Scalco, R., Wagner, K., Mercuri, E.
Published in Neuromuscular disorders : NMD (01.10.2023)
Published in Neuromuscular disorders : NMD (01.10.2023)
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21O RAINBOWFISH: 2-year efficacy and safety data of risdiplam in infants with presymptomatic SMA
Servais, L., Finkel, R., Farrar, M., Vlodavets, D., Zanoteli, E., Al-Muhaizea, M., Araújo, A., Nelson, L., Jaber, B., Gorni, K., Kletzl, H., Palfreeman, L., Gaki, E., Rabbia, M., Summers, D., Fontoura, P., Bertini, E.
Published in Neuromuscular disorders : NMD (01.10.2024)
Published in Neuromuscular disorders : NMD (01.10.2024)
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P.210 Safety, tolerability, pharmacokinetics and metabolism of balovaptan, a selective vasopressin 1a receptor antagonist, in healthy subjects
Derks, M., Lennon-Chrimes, S., Guenther, A., Squassante, L., Wandel, C., Paehler, A., Kletzl, H.
Published in European neuropsychopharmacology (01.12.2019)
Published in European neuropsychopharmacology (01.12.2019)
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P.141 Manoeuvre study design: A study of GYM329 (RO7204239) in patients with facioscapulohumeral muscular dystrophy (FSHD)
Vissing, J., Eichinger, K., Morrow, J., Statland, J., Tasca, G., Dodman, A., Jaber, B., Kletzl, H., McIver, T., Scalco, R., Yeung, W., Gaki, E., Wagner, K.
Published in Neuromuscular disorders : NMD (01.10.2022)
Published in Neuromuscular disorders : NMD (01.10.2022)
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P.110 JEWELFISH: 24-month safety and pharmacodynamic data in non-treatment-naïve patients with spinal muscular atrophy (SMA)
Chiriboga, C., Bruno, C., Duong, T., Fischer, D., Kirschner, J., Scoto, M., Mercuri, E., Gerber, M., Gorni, K., Kletzl, H., Carruthers, I., Martin, C., Gidaro, T., Muntoni, F.
Published in Neuromuscular disorders : NMD (01.10.2022)
Published in Neuromuscular disorders : NMD (01.10.2022)
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P212 RAINBOWFISH: Primary efficacy and safety data in risdiplam-treated infants with presymptomatic spinal muscular atrophy (SMA)
Finkel, R., Farrar, M., Servais, L., Vlodavets, D., Zanoteli, E., Al-Muhaizea, M., Prufer, A., Nelson, L., Fischer, C., Gerber, M., Gorni, K., Kletzl, H., Palfreeman, L., Gaki, E., Fontoura, P., Bertini, E.
Published in Neuromuscular disorders : NMD (01.10.2023)
Published in Neuromuscular disorders : NMD (01.10.2023)
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SMA - TREATMENT: EP.279 JEWELFISH: Safety, pharmacodynamic and exploratory efficacy data in non-naïve patients with spinal muscular atrophy (SMA) receiving risdiplam
Chiriboga, C., Bruno, C., Duong, T., Fischer, D., Kirschner, J., Mercuri, E., Gerber, M., Gorni, K., Kletzl, H., Carruthers, I., Martin, C., Warren, F., Scoto, M.
Published in Neuromuscular disorders : NMD (01.10.2021)
Published in Neuromuscular disorders : NMD (01.10.2021)
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Journal Article
SMA - TREATMENT
Chiriboga, C., Bruno, C., Duong, T., Fischer, D., Kirschner, J., Mercuri, E., Gerber, M., Gorni, K., Kletzl, H., Carruthers, I., Martin, C., Warren, F., Scoto, M.
Published in Neuromuscular disorders : NMD (01.10.2021)
Published in Neuromuscular disorders : NMD (01.10.2021)
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Journal Article
6587 POSTER A phase IB, dose-finding study of erlotinib in combination with pemetrexed in patients with advanced (stage IIIB/IV) non-small-cell lung cancer (NSCLC): a preliminary analysis of the BP18193 study
Ranson, M, Reck, M, Anthoney, A, Hanauske, A, Akimov, M, Klingelschmitt, G, Kletzl, H, Twelves, C
Published in European journal of cancer supplements (2007)
Published in European journal of cancer supplements (2007)
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FP.24 RAINBOWFISH: Preliminary efficacy and safety data in risdiplam-treated infants with presymptomatic spinal muscular atrophy (SMA)
Finkel, R., Farrar, M., Vlodavets, D., Zanoteli, E., Al-Muhaizea, M., Nelson, L., Prufer, A., Servais, L., Wang, Y., Fisher, C., Gerber, M., Gorni, K., Kletzl, H., Palfreeman, L., Scalco, R., Bertini, E.
Published in Neuromuscular disorders : NMD (01.10.2022)
Published in Neuromuscular disorders : NMD (01.10.2022)
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P.363JEWELFISH: safety and pharmacodynamic data in patients with spinal muscular atrophy (SMA) receiving treatment with risdiplam (RG7916) that have previously been treated with nusinersen
Chiriboga, C., Mercuri, E., Fischer, D., Day, J., Kraus, D., Yeung, W., Kletzl, H., Gerber, M., Cleary, Y., Gorni, K.
Published in Neuromuscular disorders : NMD (01.10.2019)
Published in Neuromuscular disorders : NMD (01.10.2019)
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SMA – THERAPY: P.273 Jewelfish: Safety and pharmacodynamic data in non-naïve patients with spinal muscular atrophy receiving treatment with risdiplam (RG7916)
Chiriboga, C., Bruno, C., Duong, T., Fischer, D., Kirschner, J., Mercuri, E., Gerber, M., Gorni, K., Kletzl, H., McIver, T., Scalco, R., Warren, F., Scoto, M.
Published in Neuromuscular disorders : NMD (01.10.2020)
Published in Neuromuscular disorders : NMD (01.10.2020)
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SMA – THERAPY
Chiriboga, C., Bruno, C., Duong, T., Fischer, D., Kirschner, J., Mercuri, E., Gerber, M., Gorni, K., Kletzl, H., McIver, T., Scalco, R., Warren, F., Scoto, M.
Published in Neuromuscular disorders : NMD (01.10.2020)
Published in Neuromuscular disorders : NMD (01.10.2020)
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Subcutaneous Ocrelizumab in Patients with Multiple Sclerosis: Results of the Phase III OCARINA II Study Authors
Newsome, SD, Krzystanek, E, Selmaj, K, Figueiredo, C, Wolf, C, Schneble, H-M, Bortolami, O, Kletzl, H, Bursic, L, Zecevic, D, Centonze, D
Published in Multiple sclerosis and related disorders (01.12.2023)
Published in Multiple sclerosis and related disorders (01.12.2023)
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Journal Article
CLINICAL TRIAL HIGHLIGHTS: O.4 RAINBOWFISH: A study of risdiplam in infants with presymptomatic spinal muscular atrophy (SMA)
Servais, L., Al-Muhaizea, M., Farrar, M., Nelson, L., Prufer, A., Finkel, R., Wang, Y., Zanoteli, E., El-Khairi, M., Gerber, M., Gorni, K., Kletzl, H., Palfreeman, L., Scalco, R., Bertini, E.
Published in Neuromuscular disorders : NMD (01.10.2021)
Published in Neuromuscular disorders : NMD (01.10.2021)
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Journal Article
CLINICAL TRIAL HIGHLIGHTS
Servais, L., Al-Muhaizea, M., Farrar, M., Nelson, L., Prufer, A., Finkel, R., Wang, Y., Zanoteli, E., El-Khairi, M., Gerber, M., Gorni, K., Kletzl, H., Palfreeman, L., Scalco, R., Bertini, E.
Published in Neuromuscular disorders : NMD (01.10.2021)
Published in Neuromuscular disorders : NMD (01.10.2021)
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Journal Article
706 POSTER A phase I dose escalation pharmacokinetic (PK) and pharmacodynamic (PD) study of weekly and twice weekly erlotinib in advanced stage solid malignancies
Chia, S, Chi, K, Kollmannsberger, C, Paton, K, Bhagat, K, D'Aloisio, S, Das-Gupta, A, Kletzl, H, Zwanziger, E, Gelmon, K
Published in European journal of cancer supplements (2007)
Published in European journal of cancer supplements (2007)
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