Specific γ-hydroxybutyrate-binding sites but loss of pharmacological effects of γ-hydroxybutyrate in GABAB(1)-deficient mice
Kaupmann, Klemens, Cryan, John F., Wellendorph, Petrine, Mombereau, Cedric, Sansig, Gilles, Klebs, Klaus, Schmutz, Markus, Froestl, Wolfgang, Van Der Putten, Herman, Mosbacher, Johannes, Bräuner-Osborne, Hans, Waldmeier, Peter, Bettler, Bernhard
Published in The European journal of neuroscience (01.11.2003)
Published in The European journal of neuroscience (01.11.2003)
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Mutagenesis and Modeling of the GABAB Receptor Extracellular Domain Support a Venus Flytrap Mechanism for Ligand Binding
Galvez, Thierry, Parmentier, Marie-Laure, Joly, Cécile, Malitschek, Barbara, Kaupmann, Klemens, Kuhn, Rainer, Bittiger, Helmut, Froestl, Wolfgang, Bettler, Bernhard, Pin, Jean-Philippe
Published in The Journal of biological chemistry (07.05.1999)
Published in The Journal of biological chemistry (07.05.1999)
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Point mutations in the transmembrane region of GABAB2 facilitate activation by the positive modulator N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) in the absence of the GABAB1 subunit
Dupuis, Delphine S, Relkovic, Dinko, Lhuillier, Loic, Mosbacher, Johannes, Kaupmann, Klemens
Published in Molecular pharmacology (01.12.2006)
Published in Molecular pharmacology (01.12.2006)
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Both GABAB receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats
Vlachou, Styliani, Paterson, Neil E, Guery, Sebastien, Kaupmann, Klemens, Froestl, Wolfgang, Banerjee, Deboshri, Finn, M.G, Markou, Athina
Published in European journal of pharmacology (25.03.2011)
Published in European journal of pharmacology (25.03.2011)
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Journal Article
Synthesis and Biological Evaluation of New Triazolo- and Imidazolopyridine ROR[gamma]t Inverse Agonists
Hintermann, Samuel, Guntermann, Christine, Mattes, Henri, Carcache, David A, Wagner, Juergen, Vulpetti, Anna, Billich, Andreas, Dawson, Janet, Kaupmann, Klemens, Kallen, Joerg, Stringer, Rowan, Orain, David
Published in ChemMedChem (01.12.2016)
Published in ChemMedChem (01.12.2016)
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Journal Article
Both GABA(B) receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats
Vlachou, Styliani, Paterson, Neil E, Guery, Sebastien, Kaupmann, Klemens, Froestl, Wolfgang, Banerjee, Deboshri, Finn, M G, Markou, Athina
Published in European journal of pharmacology (25.03.2011)
Published in European journal of pharmacology (25.03.2011)
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Journal Article
C-Terminal Interaction Is Essential for Surface Trafficking But Not for Heteromeric Assembly of GABAB Receptors
Pagano, Adriana, Rovelli, Giorgio, Mosbacher, Johannes, Lohmann, Tania, Duthey, Beatrice, Stauffer, Daniela, Ristig, Dorothee, Schuler, Valerie, Meigel, Ingeborg, Lampert, Christina, Stein, Thomas, Prezeau, Laurent, Blahos, Jaroslav, Pin, Jean-Philippe, Froestl, Wolfgang, Kuhn, Rainer, Heid, Jakob, Kaupmann, Klemens, Bettler, Bernhard
Published in The Journal of neuroscience (15.02.2001)
Published in The Journal of neuroscience (15.02.2001)
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Journal Article
Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice
Kaupmann, Klemens, Cryan, John F, Wellendorph, Petrine, Mombereau, Cedric, Sansig, Gilles, Klebs, Klaus, Schmutz, Markus, Froestl, Wolfgang, van der Putten, Herman, Mosbacher, Johannes, Bräuner-Osborne, Hans, Waldmeier, Peter, Bettler, Bernhard
Published in The European journal of neuroscience (01.11.2003)
Published in The European journal of neuroscience (01.11.2003)
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Journal Article
Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors
Kaupmann, K, Huggel, K, Heid, J, Flor, P J, Bischoff, S, Mickel, S J, McMaster, G, Angst, C, Bittiger, H, Froestl, W, Bettler, B
Published in Nature (London) (20.03.1997)
Published in Nature (London) (20.03.1997)
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Specific roles of GABAB(1) receptor isoforms in cognition
JACOBSON, Laura H, KELLY, Peter H, BETTLER, Bernhard, KAUPMANN, Klemens, CRYAN, John F
Published in Behavioural brain research (19.07.2007)
Published in Behavioural brain research (19.07.2007)
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Journal Article
The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function
Tiao, Jim Y, Bradaia, Amyaouch, Biermann, Barbara, Kaupmann, Klemens, Metz, Michaela, Haller, Corinne, Rolink, Antonius G, Pless, Elin, Barlow, Paul N, Gassmann, Martin, Bettler, Bernhard
Published in The Journal of biological chemistry (07.11.2008)
Published in The Journal of biological chemistry (07.11.2008)
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Journal Article
Specific roles of GABA(B(1)) receptor isoforms in cognition
Jacobson, Laura H, Kelly, Peter H, Bettler, Bernhard, Kaupmann, Klemens, Cryan, John F
Published in Behavioural brain research (19.07.2007)
Published in Behavioural brain research (19.07.2007)
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Journal Article
Blunted 5-HT 1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABA B1a but not GABA B1b subunit isoforms
Jacobson, Laura H, Hoyer, Daniel, Fehlmann, Dominique, Bettler, Bernhard, Kaupmann, Klemens, Cryan, John F
Published in Psychopharmacology (Berlin, Germany) (01.05.2017)
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Published in Psychopharmacology (Berlin, Germany) (01.05.2017)
Journal Article
Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors
KAUPMANN, K, HUGGEL, K, SETTLER, B, HELD, J, FLOR, P. J, BLSCHOFF, S, MICKEL, S. J, MCMASTER, G, ANGST, C, BITTIGER, H, FROESTL, W
Published in Nature (London) (20.03.1997)
Published in Nature (London) (20.03.1997)
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Journal Article
Exploring subtype selectivity and metabolic stability of a novel series of ligands for the benzodiazepine binding site of the GABA A receptor
Hintermann, Samuel, Hurth, Konstanze, Nozulak, Joachim, Tintelnot-Blomley, Marina, Aichholz, Reiner, Blanz, Joachim, Kaupmann, Klemens, Mosbacher, Johannes
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
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Journal Article
Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors
Mombereau, Cedric, Kaupmann, Klemens, van der Putten, Herman, Cryan, John F.
Published in European journal of pharmacology (16.08.2004)
Published in European journal of pharmacology (16.08.2004)
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Journal Article
Exploring subtype selectivity and metabolic stability of a novel series of ligands for the benzodiazepine binding site of the GABAA receptor
HINTERMANN, Samuel, HURTH, Konstanze, NOZULAK, Joachim, TINTELNOT-BLOMLEY, Marina, AICHHOLZ, Reiner, BLANZ, Joachim, KAUPMANN, Klemens, MOSBACHER, Johannes
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
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Journal Article
The RXR-Type Endoplasmic Reticulum-Retention/Retrieval Signal of GABA B1 Requires Distant Spacing from the Membrane to Function
Gassmann, Martin, Haller, Corinne, Stoll, Yanick, Aziz, Said Abdel, Biermann, Barbara, Mosbacher, Johannes, Kaupmann, Klemens, Bettler, Bernhard
Published in Molecular pharmacology (01.07.2005)
Published in Molecular pharmacology (01.07.2005)
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