Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients
Franssen, Laurens E, Nijhof, Inger S, Couto, Suzana, Levin, Mark-David, Bos, Gerard M J, Broijl, Annemiek, Klein, Saskia K, Ren, Yan, Wang, Maria, Koene, Harry R, Bloem, Andries C, Beeker, Aart, Faber, Laura M, van der Spek, Ellen, Raymakers, Reinier, Leguit, Roos J, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk, Mutis, Tuna, Thakurta, Anjan, Qian, Xiaozhong, van de Donk, Niels W C J
Published in Haematologica (Roma) (01.08.2018)
Published in Haematologica (Roma) (01.08.2018)
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Journal Article
Treatment patterns and clinical outcomes of asciminib in a real-world multiresistant chronic myeloid leukemia patient population
Kockerols, Camille C B, Janssen, Jeroen J W M, Blijlevens, Nicole M A, Klein, Saskia K, Van Hussen-Daenen, Laura G M, Van Gorkom, Gwendolyn G Y, Smit, Willem M, Van Balen, Peter, Biemond, Bart J, Cruijsen, Marjan J, Corsten, Maarten F, Te Boekhorst, Peter A W, Koene, Harry R, Van Sluis, Geerte L, Cornelissen, Jan J, Westerweel, Peter E
Published in Haematologica (Roma) (01.01.2023)
Published in Haematologica (Roma) (01.01.2023)
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Journal Article
Implementation of erythroid lineage analysis by flow cytometry in diagnostic models for myelodysplastic syndromes
Cremers, Eline M P, Westers, Theresia M, Alhan, Canan, Cali, Claudia, Visser-Wisselaar, Heleen A, Chitu, Dana A, van der Velden, Vincent H J, Te Marvelde, Jeroen G, Klein, Saskia K, Muus, Petra, Vellenga, Edo, de Greef, Georgina E, Legdeur, Marie-Cecile C J C, Wijermans, Pierre W, Stevens-Kroef, Marian J P L, Silva-Coelho, Pedro da, Jansen, Joop H, Ossenkoppele, Gert J, van de Loosdrecht, Arjan A
Published in Haematologica (Roma) (01.02.2017)
Published in Haematologica (Roma) (01.02.2017)
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Journal Article
Assessing frailty in myeloma: The pursuit of simplicity may sacrifice precision of predicting clinical outcomes
Groen, Kazimierz, Smits, Febe, Nasserinejad, Kazem, Levin, Mark‐David, Regelink, Josien C., Timmers, Gert‐Jan, Waal, Esther G. M., Westerman, Matthijs, Velders, Gerjo A., Heer, Koen, Leys, Rineke B. L., Kampen, Roel J. W., Stege, Claudia A. M., Seefat, Maarten R., Nijhof, Inger S., Spek, Ellen, Klein, Saskia K., Donk, Niels W. C. J., Ypma, Paula F., Zweegman, Sonja
Published in HemaSphere (01.07.2024)
Published in HemaSphere (01.07.2024)
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Maintenance with daratumumab or observation following treatment with bortezomib, thalidomide, and dexamethasone with or without daratumumab and autologous stem-cell transplant in patients with newly diagnosed multiple myeloma (CASSIOPEIA): an open-label, randomised, phase 3 trial
Moreau, Philippe, Hulin, Cyrille, Perrot, Aurore, Arnulf, Bertrand, Belhadj, Karim, Benboubker, Lotfi, Béné, Marie C, Zweegman, Sonja, Caillon, Hélène, Caillot, Denis, Corre, Jill, Delforge, Michel, Dejoie, Thomas, Doyen, Chantal, Facon, Thierry, Sonntag, Cécile, Fontan, Jean, Mohty, Mohamad, Jie, Kon-Siong, Karlin, Lionel, Kuhnowski, Frédérique, Lambert, Jérôme, Leleu, Xavier, Macro, Margaret, Orsini-Piocelle, Frédérique, Roussel, Murielle, Stoppa, Anne-Marie, van de Donk, Niels W C J, Wuillème, Soraya, Broijl, Annemiek, Touzeau, Cyrille, Tiab, Mourad, Marolleau, Jean-Pierre, Meuleman, Nathalie, Vekemans, Marie-Christiane, Westerman, Matthijs, Klein, Saskia K, Levin, Mark-David, Offner, Fritz, Escoffre-Barbe, Martine, Eveillard, Jean-Richard, Garidi, Réda, Ahmadi, Tahamtan, Krevvata, Maria, Zhang, Ke, de Boer, Carla, Vara, Sanjay, Kampfenkel, Tobias, Vanquickelberghe, Veronique, Vermeulen, Jessica, Avet-Loiseau, Hervé, Sonneveld, Pieter
Published in The lancet oncology (01.10.2021)
Published in The lancet oncology (01.10.2021)
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Journal Article
Comment on: “CYP3A422 Genotype‑Guided Dosing of Kinase Inhibitors in Cancer Patients”
Oude Munnink, Thijs H., Klein, Saskia K., Touw, Daan J.
Published in Clinical pharmacokinetics (01.06.2024)
Published in Clinical pharmacokinetics (01.06.2024)
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Journal Article
Clinical Impact of Polymerase Chain Reaction–Based Aspergillus and Azole Resistance Detection in Invasive Aspergillosis: A Prospective Multicenter Study
Huygens, Sammy, Dunbar, Albert, Buil, Jochem B, Klaassen, Corné H W, Verweij, Paul E, van Dijk, Karin, de Jonge, Nick, Janssen, Jeroen J W M, van der Velden, Walter J F M, Biemond, Bart J, Bart, Aldert, Bruns, Anke H W, Haas, Pieter-Jan A, Demandt, Astrid M P, Oudhuis, Guy, von dem Borne, Peter, van der Beek, Martha T, Klein, Saskia K, Godschalk, Peggy, Span, Lambert F R, Postma, Douwe F, Kampinga, Greetje A, Maertens, Johan, Lagrou, Katrien, Mercier, Toine, Moors, Ine, Boelens, Jerina, Selleslag, Dominik, Reynders, Marijke, Zandijk, Willemien, Doorduijn, Jeanette K, Cornelissen, Jan J, Schauwvlieghe, Alexander F A D, Rijnders, Bart J A
Published in Clinical infectious diseases (05.07.2023)
Published in Clinical infectious diseases (05.07.2023)
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Journal Article
Ixazomib, Daratumumab, and Low-Dose Dexamethasone in Frail Patients With Newly Diagnosed Multiple Myeloma: The Hovon 143 Study
Stege, Claudia A M, Nasserinejad, Kazem, van der Spek, Ellen, Bilgin, Yavuz M, Kentos, Alain, Sohne, Maaike, van Kampen, Roel J W, Ludwig, Inge, Thielen, Noortje, Durdu-Rayman, Nazik, de Graauw, Nicole C H P, van de Donk, Niels W C J, de Waal, Esther G M, Vekemans, Marie-Christiane, Timmers, Gert Jan, van der Klift, Marjolein, Soechit, Savita, Geerts, Paul A F, Silbermann, Matthijs H, Oosterveld, Margriet, Nijhof, Inger S, Sonneveld, Pieter, Klein, Saskia K, Levin, Mark-David, Zweegman, Sonja
Published in Journal of clinical oncology (01.09.2021)
Published in Journal of clinical oncology (01.09.2021)
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Journal Article
Cryoglobulinemic Vasculitis in Disguise: Cryofibrinogenemia as Variant of Monoclonal Gammopathy of Renal Significance
Gant, Christina M., Koelman, Carin A., Nguyen, Tri Q., Abrahams, Alferso C., Wetzels, Jack F.M., Duineveld, Caroline, Jak, Margot, Minnema, Monique C., Klein, Saskia K., Jacobs, Joannes F.M., Bosma, Renate J.
Published in American journal of kidney diseases (01.03.2024)
Published in American journal of kidney diseases (01.03.2024)
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Journal Article
Bortezomib, thalidomide, and dexamethasone with or without daratumumab and followed by daratumumab maintenance or observation in transplant-eligible newly diagnosed multiple myeloma: long-term follow-up of the CASSIOPEIA randomised controlled phase 3 trial
Moreau, Philippe, Hulin, Cyrille, Perrot, Aurore, Arnulf, Bertrand, Belhadj, Karim, Benboubker, Lotfi, Zweegman, Sonja, Caillon, Hélène, Caillot, Denis, Avet-Loiseau, Hervé, Delforge, Michel, Dejoie, Thomas, Facon, Thierry, Sonntag, Cécile, Fontan, Jean, Mohty, Mohamad, Jie, Kon-Siong, Karlin, Lionel, Kuhnowski, Frédérique, Lambert, Jérôme, Leleu, Xavier, Macro, Margaret, Orsini-Piocelle, Frédérique, Roussel, Murielle, Schiano de Colella, Jean Marc, van de Donk, Niels WCJ, Wuillème, Soraya, Broijl, Annemiek, Touzeau, Cyrille, Tiab, Mourad, Marolleau, Jean-Pierre, Meuleman, Nathalie, Vekemans, Marie-Christiane, Westerman, Matthijs, Klein, Saskia K, Levin, Mark-David, Offner, Fritz, Escoffre-Barbe, Martine, Eveillard, Jean-Richard, Garidi, Réda, Hua, Winnie, Wang, Jianping, Tuozzo, Alba, de Boer, Carla, Rowe, Melissa, Vanquickelberghe, Veronique, Carson, Robin, Vermeulen, Jessica, Corre, Jill, Sonneveld, Pieter
Published in The lancet oncology (01.08.2024)
Published in The lancet oncology (01.08.2024)
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Journal Article
Ixazomib-Thalidomide-low dose dexamethasone induction followed by maintenance therapy with ixazomib or placebo in newly diagnosed multiple myeloma patients not eligible for autologous stem cell transplantation; results from the randomized phase II HOVON-126/NMSG 21.13 trial
Zweegman, Sonja, Stege, Claudia A M, Haukas, Einar, Schjesvold, Fredrik H, Levin, Mark-David, Waage, Anders, Leys, Rineke B L, Klein, Saskia K, Szatkowski, Damian, Axelsson, Per, Hieu Do, Trung, Knut-Bojanowska, Dorota, van der Spek, Ellen, Svirskaite, Asta, Klostergaard, Anja, Salomo, Morten, Blimark, Celine, Ypma, Paula F, Mellqvist, Ulf-Henrik, Poddighe, Pino J, Stevens-Kroef, Marian, van de Donk, Niels W C J, Sonneveld, Pieter, Hansson, Markus, van der Holt, Bronno, Abildgaard, Niels
Published in Haematologica (Roma) (01.12.2020)
Published in Haematologica (Roma) (01.12.2020)
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Journal Article
Therapeutic drug monitoring-guided treatment versus standard dosing of voriconazole for invasive aspergillosis in haematological patients: a multicentre, prospective, cluster randomised, crossover clinical trial
Veringa, Anette, Brüggemann, Roger J., Span, Lambert F.R., Biemond, Bart J., de Boer, Mark G.J., van den Heuvel, Edwin R., Klein, Saskia K., Kraemer, Doris, Minnema, Monique C., Prakken, Niek H.J., Rijnders, Bart J.A., Swen, Jesse J., Verweij, Paul E., Wondergem, Mariëlle J., Ypma, Paula F., Blijlevens, Nicole, Kosterink, Jos G.W., van der Werf, Tjip S., Alffenaar, Jan-Willem C.
Published in International journal of antimicrobial agents (01.02.2023)
Published in International journal of antimicrobial agents (01.02.2023)
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Journal Article
Midostaurin added to 10-day decitabine, for patients unfit for intensive chemotherapy with AML and higher risk MDS, irrespective of FLT3 mutational status, does not improve outcome
Huls, Gerwin, Chitu, Dana A, Tick, Lidwine, Boersma, Rinske, Breems, Dimitri, Herbers, Alexandra, Klein, Saskia K, de Jonge, Suzan, Westerweel, Peter E, Cruijsen, Marjan, Hoogendoorn, Mels, Cuijpers, Marlous, Deeren, Dries, Bailly, Benjamin, Visser, Otto, van Rhenen, Anna, Posthuma, Eduard F M, Valk, Peter J M, Cloos, Jacqueline, Ammatuna, Emanuele, Refos, Jeannine M, Fakkert, R, Löwenberg, Bob, Ossenkoppele, Gert J
Published in Annals of hematology (05.10.2024)
Published in Annals of hematology (05.10.2024)
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Journal Article
Ixazomib-Thalidomide-low dose dexamethasone induction followed by maintenance therapy with ixazomib or placebo in newly diagnosed multiple myeloma patients not eligible for autologous stem cell transplantation; results from the randomized phase II HOVON-126/NMSG 21.13 trial
Zweegman, Sonja, Stege, Claudia A M, Haukas, Einar, Schjesvold, Fredrik H, Levin, Mark-David, Waage, Anders, Leys, Rineke B L, Klein, Saskia K, Szatkowski, Damian, Axelsson, Per, Hieu Do, Trung, Knut-Bojanowska, Dorota, van der Spek, Ellen, Svirskaite, Asta, Klostergaard, Anja, Salomo, Morten, Blimark, Celine, Ypma, Paula F, Mellqvist, Ulf-Henrik, Poddighe, Pino J, Stevens-Kroef, Marian, van de Donk, Niels W C J, Sonneveld, Pieter, Hansson, Markus, van der Holt, Bronno, Abildgaard, Niels
Published in Haematologica (Roma) (01.12.2020)
Published in Haematologica (Roma) (01.12.2020)
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Journal Article
Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma
Nijhof, Inger S., Franssen, Laurens E., Levin, Mark-David, Bos, Gerard M.J., Broijl, Annemiek, Klein, Saskia K., Koene, Harry R., Bloem, Andries C., Beeker, Aart, Faber, Laura M., van der Spek, Ellen, Ypma, Paula F., Raymakers, Reinier, van Spronsen, Dick-Johan, Westerweel, Peter E., Oostvogels, Rimke, van Velzen, Jeroen, van Kessel, Berris, Mutis, Tuna, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk M., van de Donk, Niels W.C.J.
Published in Blood (10.11.2016)
Published in Blood (10.11.2016)
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Journal Article
Central nervous system localisation of chronic lymphocytic leukaemia, description of two very distinct cases and a review of the literature
Timmers, Nyanza K. L. M., de Maar, Josanne S., van Kruijsdijk, Rob C. M., Klein, Saskia K.
Published in Annals of hematology (01.09.2018)
Published in Annals of hematology (01.09.2018)
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Journal Article
Efficacy and safety of daratumumab combined with all-trans retinoic acid in relapsed/refractory multiple myeloma
Frerichs, Kristine A., Minnema, Monique C., Levin, Mark-David, Broijl, Annemiek, Bos, Gerard M.J., Kersten, Marie José, Mutis, Tuna, Verkleij, Christie P.M., Nijhof, Inger S., Maas-Bosman, Patricia W.C., Klein, Saskia K., Zweegman, Sonja, Sonneveld, Pieter, van de Donk, Niels W.C.J.
Published in Blood advances (14.12.2021)
Published in Blood advances (14.12.2021)
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Journal Article
Lenalidomide combined with low-dose cyclophosphamide and prednisone modulates Ikaros and Aiolos in lymphocytes, resulting in immunostimulatory effects in lenalidomide-refractory multiple myeloma patients
Franssen, Laurens E, Nijhof, Inger S, Bjorklund, Chad C, Chiu, Hsiling, Doorn, Ruud, van Velzen, Jeroen, Emmelot, Maarten, van Kessel, Berris, Levin, Mark-David, Bos, Gerard M J, Broijl, Annemiek, Klein, Saskia K, Koene, Harry R, Bloem, Andries C, Beeker, Aart, Faber, Laura M, van der Spek, Ellen, Raymakers, Reinier, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk M, Thakurta, Anjan, Qian, Xiaozhong, Mutis, Tuna, van de Donk, Niels W C J
Published in Oncotarget (21.09.2018)
Published in Oncotarget (21.09.2018)
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Journal Article
Genomic array as compared to karyotyping in myelodysplastic syndromes in a prospective clinical trial
Stevens‐Kroef, Marian J., Olde Weghuis, Daniel, ElIdrissi‐Zaynoun, Najat, van der Reijden, Bert, Cremers, Eline M. P., Alhan, Canan, Westers, Theresia M., Visser‐Wisselaar, Heleen A., Chitu, Dana A., Cunha, Sonia M., Vellenga, Edo, Klein, Saskia K., Wijermans, Pierre, de Greef, Georgine E., Schaafsma, M. Ron, Muus, Petra, Ossenkoppele, Gert J., van de Loosdrecht, Arjan A., Jansen, Joop H.
Published in Genes chromosomes & cancer (01.07.2017)
Published in Genes chromosomes & cancer (01.07.2017)
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