Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers
van Dissel, Jaap T, Arend, Sandra M, Prins, Corine, Bang, Peter, Tingskov, Pernille Nyholm, Lingnau, Karen, Nouta, Jan, Klein, Michèl R, Rosenkrands, Ida, Ottenhoff, Tom H.M, Kromann, Ingrid, Doherty, T. Mark, Andersen, Peter
Published in Vaccine (30.04.2010)
Published in Vaccine (30.04.2010)
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Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis
Leyten, Eliane M.S., Lin, May Young, Franken, Kees L.M.C., Friggen, Annemieke H., Prins, Corine, van Meijgaarden, Krista E., Voskuil, Martin I., Weldingh, Karin, Andersen, Peter, Schoolnik, Gary K., Arend, Sandra M., Ottenhoff, Tom H.M., Klein, Michèl R.
Published in Microbes and infection (01.07.2006)
Published in Microbes and infection (01.07.2006)
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Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA–PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice
Bivas-Benita, Maytal, Lin, May Young, Bal, Suzanne M, van Meijgaarden, Krista E, Franken, Kees L.M.C, Friggen, Annemieke H, Junginger, Hans E, Borchard, Gerrit, Klein, Michèl R, Ottenhoff, Tom H.M
Published in Vaccine (19.06.2009)
Published in Vaccine (19.06.2009)
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Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area
Chegou, Novel N, Essone, Paulin N, Loxton, Andre G, Stanley, Kim, Black, Gillian F, van der Spuy, Gian D, van Helden, Paul D, Franken, Kees L, Parida, Shreemanta K, Klein, Michel R, Kaufmann, Stefan H E, Ottenhoff, Tom H M, Walzl, Gerhard
Published in PloS one (05.06.2012)
Published in PloS one (05.06.2012)
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Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection
Caccamo, Nadia, Guggino, Giuliana, Meraviglia, Serena, Gelsomino, Giuseppe, Di Carlo, Paola, Titone, Lucina, Bocchino, Marialuisa, Galati, Domenico, Matarese, Alessandro, Nouta, Jan, Klein, Michel R, Salerno, Alfredo, Sanduzzi, Alessandro, Dieli, Francesco, Ottenhoff, Tom H M
Published in PloS one (13.05.2009)
Published in PloS one (13.05.2009)
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Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting
Chegou, Novel N, Black, Gillian F, Loxton, Andre G, Stanley, Kim, Essone, Paulin N, Klein, Michel R, Parida, Shreemanta K, Kaufmann, Stefan H E, Doherty, T Mark, Friggen, Annemieke H, Franken, Kees L, Ottenhoff, Tom H, Walzl, Gerhard
Published in BMC infectious diseases (20.01.2012)
Published in BMC infectious diseases (20.01.2012)
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Cross-Reactive Immunity to Mycobacterium tuberculosis DosR Regulon-Encoded Antigens in Individuals Infected with Environmental, Nontuberculous Mycobacteria
Lin, May Young, Reddy, T.B.K, Arend, Sandra M, Friggen, Annemieke H, Franken, Kees L.M.C, van Meijgaarden, Krista E, Verduyn, Marleen J.C, Schoolnik, Gary K, Klein, Michel R, Ottenhoff, Tom H.M
Published in Infection and Immunity (01.11.2009)
Published in Infection and Immunity (01.11.2009)
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Monokine induced by interferon gamma and IFN-γ response to a fusion protein of Mycobacterium tuberculosis ESAT-6 and CFP-10 in Brazilian tuberculosis patients
Abramo, Clarice, Meijgaarden, Krista E., Garcia, Daniely, Franken, Kees L.M.C., Klein, Michèl R., Kolk, Arend J., Oliveira, Sérgio C., Ottenhoff, Tom H.M., Teixeira, Henrique C.
Published in Microbes and infection (2006)
Published in Microbes and infection (2006)
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ESAT-6/CFP-10 Fusion Protein and Peptides for Optimal Diagnosis of Mycobacterium tuberculosis Infection by Ex Vivo Enzyme-Linked Immunospot Assay in The Gambia
Hill, Philip C, Jackson-Sillah, Dolly, Fox, Annette, Franken, Kees L. M. C, Lugos, Moses D, Jeffries, David J, Donkor, Simon A, Hammond, Abdulrahman S, Adegbola, Richard A, Ottenhoff, Tom H. M, Klein, Michel R, Brookes, Roger H
Published in Journal of Clinical Microbiology (01.05.2005)
Published in Journal of Clinical Microbiology (01.05.2005)
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Immunogenicity of Eight Dormancy Regulon-Encoded Proteins of Mycobacterium tuberculosis in DNA-Vaccinated and Tuberculosis-Infected Mice
Roupie, Virginie, Romano, Marta, Zhang, Lei, Korf, Hannelie, Lin, May Young, Franken, Kees L.M.C, Ottenhoff, Tom H.M, Klein, Michèl R, Huygen, Kris
Published in Infection and Immunity (01.02.2007)
Published in Infection and Immunity (01.02.2007)
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Consistent Associations of HLA Class I and II and Transporter Gene Products with Progression of Human Immunodeficiency Virus Type 1 Infection in Homosexual Men
Keet, Ireneus P. M., Tang, James, Klein, Michèl R., LeBlanc, Susan, Enger, Cheryl, Rivers, Charles, Apple, Raymond J., Mann, Dean, Goedert, James J., Miedema, Frank, Kaslow, Richard A.
Published in The Journal of infectious diseases (01.08.1999)
Published in The Journal of infectious diseases (01.08.1999)
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Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity
Joosten, Simone A, van Meijgaarden, Krista E, van Weeren, Pascale C, Kazi, Fatima, Geluk, Annemieke, Savage, Nigel D L, Drijfhout, Jan W, Flower, Darren R, Hanekom, Willem A, Klein, Michèl R, Ottenhoff, Tom H M
Published in PLoS pathogens (26.02.2010)
Published in PLoS pathogens (26.02.2010)
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T-Cell Recognition of the HspX Protein of Mycobacterium tuberculosis Correlates with Latent M. tuberculosis Infection but Not with M. bovis BCG Vaccination
Geluk, Annemieke, Lin, May Young, van Meijgaarden, Krista E, Leyten, Eliane M.S, Franken, Kees L.M.C, Ottenhoff, Tom H.M, Klein, Michèl R
Published in Infection and Immunity (01.06.2007)
Published in Infection and Immunity (01.06.2007)
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Identification of a human CD8⁺ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4
Joosten, Simone A, van Meijgaarden, Krista E, Savage, Nigel D.L, de Boer, Tjitske, Triebel, Frédéric, van der Wal, Annemieke, de Heer, Emile, Klein, Michèl R, Geluk, Annemieke, Ottenhoff, Tom H.M
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2007)
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Lack of Immune Responses to Mycobacterium tuberculosis DosR Regulon Proteins following Mycobacterium bovis BCG Vaccination
Lin, May Young, Geluk, Annemieke, Smith, Steven G, Stewart, Amanda L, Friggen, Annemieke H, Franken, Kees L.M.C, Verduyn, Marleen J.C, van Meijgaarden, Krista E, Voskuil, Martin I, Dockrell, Hazel M, Huygen, Kris, Ottenhoff, Tom H.M, Klein, Michèl R
Published in Infection and Immunity (01.07.2007)
Published in Infection and Immunity (01.07.2007)
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Genome-based in silico identification of new Mycobacterium tuberculosis antigens activating polyfunctional CD8+ T cells in human tuberculosis
Tang, Sheila T, van Meijgaarden, Krista E, Caccamo, Nadia, Guggino, Giuliana, Klein, Michèl R, van Weeren, Pascale, Kazi, Fatima, Stryhn, Anette, Zaigler, Alexander, Sahin, Ugur, Buus, Søren, Dieli, Francesco, Lund, Ole, Ottenhoff, Tom H M
Published in The Journal of immunology (1950) (15.01.2011)
Published in The Journal of immunology (1950) (15.01.2011)
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Immunogenicity of Novel DosR Regulon-Encoded Candidate Antigens of Mycobacterium tuberculosis in Three High-Burden Populations in Africa
Black, Gillian F, Thiel, Bonnie A, Ota, Martin O, Parida, Shreemanta K, Adegbola, Richard, Boom, W Henry, Dockrell, Hazel M, Franken, Kees L M C, Friggen, Annemiek H, Hill, Philip C, Klein, Michel R, Lalor, Maeve K, Mayanja, Harriet, Schoolnik, Gary, Stanley, Kim, Weldingh, Karin, Kaufmann, Stefan H E, Walzl, Gerhard, Ottenhoff, Tom H M
Published in Clinical and Vaccine Immunology (01.08.2009)
Published in Clinical and Vaccine Immunology (01.08.2009)
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Vigorous but Short-Term Gamma Interferon T-Cell Responses against a Dominant HLA-A02-Restricted Measles Virus Epitope in Patients with Measles
Jaye, Assan, Herberts, Carla A, Jallow, Sabelle, Atabani, Sowsan, Klein, Michel R, Hoogerhout, Peter, Kidd, Michael, van Els, Cécile A C M, Whittle, Hilton C
Published in Journal of Virology (01.04.2003)
Published in Journal of Virology (01.04.2003)
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Mycobacterium bovis BCG Vaccine Strains Lack narK2 and narX Induction and Exhibit Altered Phenotypes during Dormancy
Honaker, Ryan W, Stewart, Amanda, Schittone, Stephanie, Izzo, Angelo, Klein, Michèl R, Voskuil, Martin I
Published in Infection and Immunity (01.06.2008)
Published in Infection and Immunity (01.06.2008)
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