Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation
Lastres-Becker, Isabel, Nonis, David, Eich, Florian, Klinkenberg, Michael, Gorospe, Myriam, Kötter, Peter, Klein, Fabrice A.C., Kedersha, Nancy, Auburger, Georg
Published in Biochimica et biophysica acta (01.09.2016)
Published in Biochimica et biophysica acta (01.09.2016)
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Journal Article
The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation
MALLARET, Martial, SYNOFZIK, Matthis, TRANCHANT, Christine, MIGNOT, Cyril, MANDEL, Jean-Louis, BEDFORD, Mark, BAUER, Peter, SALIH, Mustafa A, SCHÜLE, Rebecca, SCHÖLS, Ludger, ALDAZ, C. Marcelo, KOENIG, Michel, JAEHO LEE, SAGUM, Cari A, MAHAJNAH, Muhammad, SHARKIA, Rajech, DROUOT, Nathalie, RENAUD, Mathilde, KLEIN, Fabrice A. C, ANHEIM, Mathieu
Published in Brain (London, England : 1878) (01.02.2014)
Published in Brain (London, England : 1878) (01.02.2014)
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Journal Article
SynAggreg: A Multifunctional High-Throughput Technology for Precision Study of Amyloid Aggregation and Systematic Discovery of Synergistic Inhibitor Compounds
Aviolat, Hubert, Nominé, Yves, Gioria, Sophie, Bonhoure, Anna, Hoffmann, David, Ruhlmann, Christine, Nierengarten, Hélène, Ruffenach, Frank, Villa, Pascal, Trottier, Yvon, Klein, Fabrice A.C.
Published in Journal of molecular biology (07.12.2018)
Published in Journal of molecular biology (07.12.2018)
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Journal Article
Linear and extended: a common polyglutamine conformation recognized by the three antibodies MW1, 1C2 and 3B5H10
Klein, Fabrice A C, Zeder-Lutz, Gabrielle, Cousido-Siah, Alexandra, Mitschler, André, Katz, Aline, Eberling, Pascal, Mandel, Jean-Louis, Podjarny, Alberto, Trottier, Yvon
Published in Human molecular genetics (15.10.2013)
Published in Human molecular genetics (15.10.2013)
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Journal Article
Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease
Seefelder, Manuel, Klein, Fabrice A.C., Landwehrmeyer, Bernhard, Fernández-Busnadiego, Rubén, Kochanek, Stefan
Published in Journal of Huntington's Disease (01.01.2022)
Published in Journal of Huntington's Disease (01.01.2022)
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Book Review
Journal Article
Structure of a Single-Chain Fv Bound to the 17 N-Terminal Residues of Huntingtin Provides Insights into Pathogenic Amyloid Formation and Suppression
De Genst, Erwin, Chirgadze, Dimitri Y., Klein, Fabrice A.C., Butler, David C., Matak-Vinković, Dijana, Trottier, Yvon, Huston, James S., Messer, Anne, Dobson, Christopher M.
Published in Journal of molecular biology (19.06.2015)
Published in Journal of molecular biology (19.06.2015)
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Journal Article
Huntingtin affinity for partners is not changed by polyglutamine length: aggregation itself triggers aberrant interactions
Davranche, Aurélien, Aviolat, Hubert, Zeder-Lutz, Gabrielle, Busso, Didier, Altschuh, Danièle, Trottier, Yvon, Klein, Fabrice A.C.
Published in Human molecular genetics (15.07.2011)
Published in Human molecular genetics (15.07.2011)
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Journal Article
Pathogenic and Non-pathogenic Polyglutamine Tracts Have Similar Structural Properties: Towards a Length-dependent Toxicity Gradient
Klein, Fabrice A.C., Pastore, Annalisa, Masino, Laura, Zeder-Lutz, Gabrielle, Nierengarten, Hélène, Oulad-Abdelghani, Mustapha, Altschuh, Danièle, Mandel, Jean-Louis, Trottier, Yvon
Published in Journal of molecular biology (03.08.2007)
Published in Journal of molecular biology (03.08.2007)
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Journal Article
Biochemical and NMR mapping of the interface between CREB-binding protein and ligand binding domains of nuclear receptor: beyond the LXXLL motif
Klein, Fabrice A C, Atkinson, R Andrew, Potier, Noelle, Moras, Dino, Cavarelli, Jean
Published in The Journal of biological chemistry (18.02.2005)
Published in The Journal of biological chemistry (18.02.2005)
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Journal Article