Brain Disorders Due to Lysosomal Dysfunction
Fraldi, Alessandro, Klein, Andrés D, Medina, Diego L, Settembre, Carmine
Published in Annual review of neuroscience (08.07.2016)
Published in Annual review of neuroscience (08.07.2016)
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Journal Article
RIPK3 as a potential therapeutic target for Gaucher's disease
Vitner, Einat B, Salomon, Ran, Farfel-Becker, Tamar, Meshcheriakova, Anna, Ali, Mohammad, Klein, Andrés D, Platt, Frances M, Cox, Timothy M, Futerman, Anthony H
Published in Nature medicine (01.02.2014)
Published in Nature medicine (01.02.2014)
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Journal Article
Delineating pathological pathways in a chemically induced mouse model of Gaucher disease
Vardi, Ayelet, Zigdon, Hila, Meshcheriakova, Anna, Klein, Andrés D, Yaacobi, Chen, Eilam, Raya, Kenwood, Brandon M, Rahim, Ahad A, Massaro, Giulia, Merrill Jr, Alfred H, Vitner, Einat B, Futerman, Anthony H
Published in The Journal of pathology (01.08.2016)
Published in The Journal of pathology (01.08.2016)
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Journal Article
Anatomically defined neuron-based rescue of neurodegenerative Niemann-Pick type C disorder
Lopez, Manuel E, Klein, Andres D, Dimbil, Ubah J, Scott, Matthew P
Published in The Journal of neuroscience (23.03.2011)
Published in The Journal of neuroscience (23.03.2011)
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Journal Article
Npc1 deficiency in the C57BL/6J genetic background enhances Niemann–Pick disease type C spleen pathology
Parra, Julio, Klein, Andrés D., Castro, Juan, Morales, María Gabriela, Mosqueira, Matías, Valencia, Ilse, Cortés, Victor, Rigotti, Attilio, Zanlungo, Silvana
Published in Biochemical and biophysical research communications (30.09.2011)
Published in Biochemical and biophysical research communications (30.09.2011)
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Journal Article
Complement is dispensable for neurodegeneration in Niemann-Pick disease type C
Lopez, Manuel E, Klein, Andres D, Scott, Matthew P
Published in Journal of neuroinflammation (17.09.2012)
Published in Journal of neuroinflammation (17.09.2012)
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Journal Article
Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage
Balboa, Elisa, Marín, Tamara, Oyarzún, Juan Esteban, Contreras, Pablo S., Hardt, Robert, van den Bosch, Thea, Alvarez, Alejandra R., Rebolledo-Jaramillo, Boris, Klein, Andres D., Winter, Dominic, Zanlungo, Silvana
Published in Cells (Basel, Switzerland) (21.08.2021)
Published in Cells (Basel, Switzerland) (21.08.2021)
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Journal Article
Modeling Parkinson’s Disease Heterogeneity to Accelerate Precision Medicine
Olivares, Gonzalo H., Olguín, Patricio, Klein, Andrés D.
Published in Trends in molecular medicine (01.12.2019)
Published in Trends in molecular medicine (01.12.2019)
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Journal Article
Genetic Background Matters: Population-Based Studies in Model Organisms for Translational Research
Olguín, Valeria, Durán, Anyelo, Las Heras, Macarena, Rubilar, Juan Carlos, Cubillos, Francisco A, Olguín, Patricio, Klein, Andrés D
Published in International journal of molecular sciences (08.07.2022)
Published in International journal of molecular sciences (08.07.2022)
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Journal Article
Rare diseases in Chile: challenges and recommendations in universal health coverage context
Encina, Gonzalo, Castillo-Laborde, Carla, Lecaros, Juan A, Dubois-Camacho, Karen, Calderón, Juan F, Aguilera, Ximena, Klein, Andrés D, Repetto, Gabriela M
Published in Orphanet journal of rare diseases (11.12.2019)
Published in Orphanet journal of rare diseases (11.12.2019)
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Journal Article
A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids
Durán, Anyelo, Priestman, David A, Las Heras, Macarena, Rebolledo-Jaramillo, Boris, Olguín, Valeria, Calderón, Juan F, Zanlungo, Silvana, Gutiérrez, Jaime, Platt, Frances M, Klein, Andrés D
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Journal Article
Gadolinium Chloride Rescues Niemann⁻Pick Type C Liver Damage
Klein, Andrés D, Oyarzún, Juan Esteban, Cortez, Cristian, Zanlungo, Silvana
Published in International journal of molecular sciences (14.11.2018)
Published in International journal of molecular sciences (14.11.2018)
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Journal Article
Lack of Annexin A6 Exacerbates Liver Dysfunction and Reduces Lifespan of Niemann-Pick Type C Protein–Deficient Mice
Meneses-Salas, Elsa, Garcia-Forn, Marta, Castany-Pladevall, Carla, Lu, Albert, Fajardo, Alba, Jose, Jaimy, Wahba, Mohamed, Bosch, Marta, Pol, Albert, Tebar, Francesc, Klein, Andrés D., Zanlungo, Silvana, Pérez-Navarro, Esther, Grewal, Thomas, Enrich, Carlos, Rentero, Carles
Published in The American journal of pathology (01.03.2021)
Published in The American journal of pathology (01.03.2021)
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Journal Article
Role of proteases in dysfunctional placental vascular remodelling in preeclampsia
Gutiérrez, Jaime A., Gómez, Isabel, Chiarello, Delia I., Salsoso, Rocío, Klein, Andrés D., Guzmán-Gutiérrez, Enrique, Toledo, Fernando, Sobrevia, Luis
Published in Biochimica et biophysica acta. Molecular basis of disease (01.02.2020)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.02.2020)
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Journal Article