Randomized placebo-controlled dose-ranging and pharmacodynamics study of roxadustat (FG-4592) to treat anemia in nondialysis-dependent chronic kidney disease (NDD-CKD) patients
Besarab, Anatole, Provenzano, Robert, Hertel, Joachim, Zabaneh, Raja, Klaus, Stephen J, Lee, Tyson, Leong, Robert, Hemmerich, Stefan, Yu, Kin-Hung Peony, Neff, Thomas B
Published in Nephrology, dialysis, transplantation (01.10.2015)
Published in Nephrology, dialysis, transplantation (01.10.2015)
Get full text
Journal Article
Connective tissue growth factor–specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer
Aikawa, Takuma, Gunn, Jason, Spong, Suzanne M, Klaus, Stephen J, Korc, Murray
Published in Molecular cancer therapeutics (01.05.2006)
Published in Molecular cancer therapeutics (01.05.2006)
Get full text
Journal Article
HIF–prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques
Hsieh, Matthew M., Linde, N. Seth, Wynter, Aisha, Metzger, Mark, Wong, Carol, Langsetmo, Ingrid, Lin, Al, Smith, Reginald, Rodgers, Griffin P., Donahue, Robert E., Klaus, Stephen J., Tisdale, John F.
Published in Blood (15.09.2007)
Published in Blood (15.09.2007)
Get full text
Journal Article
Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer
Seeley, Todd W, Sternlicht, Mark D, Klaus, Stephen J, Neff, Thomas B, Liu, David Y
Published in Hypoxia (01.01.2017)
Published in Hypoxia (01.01.2017)
Get full text
Journal Article
Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization
Paliege, Alexander, Rosenberger, Christian, Bondke, Anja, Sciesielski, Lina, Shina, Ahuva, Heyman, Samuel N., Flippin, Lee A., Arend, Michael, Klaus, Stephen J., Bachmann, Sebastian
Published in Kidney international (01.02.2010)
Published in Kidney international (01.02.2010)
Get full text
Journal Article
An Endoplasmic Reticulum Transmembrane Prolyl 4-Hydroxylase Is Induced by Hypoxia and Acts on Hypoxia-inducible Factor α
Koivunen, Peppi, Tiainen, Päivi, Hyvärinen, Jaana, Williams, Kim E., Sormunen, Raija, Klaus, Stephen J., Kivirikko, Kari I., Myllyharju, Johanna
Published in The Journal of biological chemistry (19.10.2007)
Published in The Journal of biological chemistry (19.10.2007)
Get full text
Journal Article
Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney
Rosenberger, Christian, Rosen, Seymour, Shina, Ahuva, Frei, Ulrich, Eckardt, Kai-Uwe, Flippin, Lee A., Arend, Michael, Klaus, Stephen J., Heyman, Samuel N.
Published in Nephrology, dialysis, transplantation (01.11.2008)
Published in Nephrology, dialysis, transplantation (01.11.2008)
Get full text
Journal Article
Prevention of Experimental Allergic Encephalomyelitis via Inhibition of IL-12 Signaling and IL-12-Mediated Th1 Differentiation: An Effect of the Novel Anti-Inflammatory Drug Lisofylline
Bright, John J, Du, Caigan, Coon, Michael, Sriram, Subramaniam, Klaus, Stephen J
Published in The Journal of immunology (1950) (15.12.1998)
Published in The Journal of immunology (1950) (15.12.1998)
Get full text
Journal Article
Protein Kinase C μ (PKCμ) Associates with the B Cell Antigen Receptor Complex and Regulates Lymphocyte Signaling
Sidorenko, Svetlana P, Law, Che-Leung, Klaus, Stephen J, Chandran, Karen A, Takata, Minoru, Kurosaki, Tomohiro, Clark, Edward A
Published in Immunity (Cambridge, Mass.) (01.10.1996)
Published in Immunity (Cambridge, Mass.) (01.10.1996)
Get full text
Journal Article
CD22 regulates thymus-independent responses and the lifespan of B cells
Otipoby, Kevin L, Andersson, Kristin B, Draves, Kevin E, Klaus, Stephen J, Farr, Andrew G, Kerner, James D, Perlmutter, Roger M, Law, Che-Leung, Clark, Edward A
Published in Nature (London) (01.12.1996)
Published in Nature (London) (01.12.1996)
Get full text
Journal Article
CD22 regulates thymus-independent responses and the lifespan of B cells
Otipoby, K L, Andersson, K B, Draves, K E, Klaus, S J, Farr, A G, Kerner, J D, Perlmutter, R M, Law, C L, Clark, E A
Published in Nature (London) (19.12.1996)
Published in Nature (London) (19.12.1996)
Get full text
Journal Article
Hypoxia-inducible factor-2[alpha]-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization
Paliege, Alexander, Rosenberger, Christian, Bondke, Anja, Sciesielski, Lina, Shina, Ahuva, Heyman, Samuel N, Flippin, Lee A, Arend, Michael, Klaus, Stephen J, Bachmann, Sebastian
Published in Kidney international (01.02.2010)
Published in Kidney international (01.02.2010)
Get full text
Journal Article
An Endoplasmic Reticulum Transmembrane Prolyl 4-Hydroxylase Is Induced by Hypoxia and Acts on Hypoxia-inducible Factor Î
Peppi Koivunen, Päivi Tiainen, Jaana Hyvärinen, Kim E. Williams, Raija Sormunen, Stephen J. Klaus, Kari I. Kivirikko, Johanna Myllyharju
Published in The Journal of biological chemistry (19.10.2007)
Published in The Journal of biological chemistry (19.10.2007)
Get full text
Journal Article
Functional CD40 ligand expressed by human blood dendritic cells is up- regulated by CD40 ligation
Pinchuk, LM, Klaus, SJ, Magaletti, DM, Pinchuk, GV, Norsen, JP, Clark, EA
Published in The Journal of immunology (1950) (15.11.1996)
Published in The Journal of immunology (1950) (15.11.1996)
Get full text
Journal Article
Costimulation through CD28 enhances T cell-dependent B cell activation via CD40-CD40L interaction
Klaus, SJ, Pinchuk, LM, Ochs, HD, Law, CL, Fanslow, WC, Armitage, RJ, Clark, EA
Published in The Journal of immunology (1950) (15.06.1994)
Published in The Journal of immunology (1950) (15.06.1994)
Get full text
Journal Article
ENHANCED ERYTHROPOIESIS AND IRON METABOLISM
KLAUS, Stephen J, NEFF, Thomas B, MOLINEAUX, Christopher J, LANGSETMO PAROBOK, Ingrid, STEPHENSON, Robert C, SEELEY, Todd W, GUENZLER-PUKALL, Volkmar
Year of Publication 06.06.2024
Get full text
Year of Publication 06.06.2024
Patent
Enhanced erythropoiesis and iron metabolism
Klaus, Stephen J, Guenzler-Pukall, Volkmar, Lin, Al Y, Neff, Thomas B, Flippin, Lee A, Arend, Michael P, Wang, Qingjian
Year of Publication 20.06.2023
Get full text
Year of Publication 20.06.2023
Patent