Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer
Julien, Jean-Philippe, Cupo, Albert, Sok, Devin, Stanfield, Robyn L., Lyumkis, Dmitry, Deller, Marc C., Klasse, Per-Johan, Burton, Dennis R., Sanders, Rogier W., Moore, John P., Ward, Andrew B., Wilson, Ian A.
Published in Science (American Association for the Advancement of Science) (20.12.2013)
Published in Science (American Association for the Advancement of Science) (20.12.2013)
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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
Lyumkis, Dmitry, Julien, Jean-Philippe, de Val, Natalia, Cupo, Albert, Potter, Clinton S., Klasse, Per-Johan, Burton, Dennis R., Sanders, Rogier W., Moore, John P., Carragher, Bridget, Wilson, Ian A., Ward, Andrew B.
Published in Science (American Association for the Advancement of Science) (20.12.2013)
Published in Science (American Association for the Advancement of Science) (20.12.2013)
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Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens
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Published in eLife (04.08.2020)
Published in eLife (04.08.2020)
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Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer
Derking, Ronald, Ozorowski, Gabriel, Sliepen, Kwinten, Yasmeen, Anila, Cupo, Albert, Torres, Jonathan L, Julien, Jean-Philippe, Lee, Jeong Hyun, van Montfort, Thijs, de Taeye, Steven W, Connors, Mark, Burton, Dennis R, Wilson, Ian A, Klasse, Per-Johan, Ward, Andrew B, Moore, John P, Sanders, Rogier W
Published in PLoS pathogens (01.03.2015)
Published in PLoS pathogens (01.03.2015)
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Multiple CCR5 Conformations on the Cell Surface Are Used Differentially by Human Immunodeficiency Viruses Resistant or Sensitive to CCR5 Inhibitors
BERRO, Reem, JOHAN KLASSE, Per, LASCANO, Danny, FLEGLER, Ayanna, NAGASHIMA, Kirsten A, SANDERS, Rogier W, SAKMAR, Thomas P, HOPE, Thomas J, MOORE, John P
Published in Journal of Virology (01.08.2011)
Published in Journal of Virology (01.08.2011)
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Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques
MALCOLM, R. Karl, VEAZEY, Ronald S, DOYLE, Lara A, RASMUSSEN, Kelsi K, GOLDMAN, Laurie, KETAS, Thomas J, MOORE, John P, GEER, Leslie, LOWRY, Deborah, FETHERSTON, Susan M, MURPHY, Diarmaid J, BOYD, Peter, MAJOR, Ian, SHATTOCK, Robin J, KLASSE, Per Johan
Published in Antimicrobial Agents and Chemotherapy (01.05.2012)
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Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles
Brouwer, Philip J. M., Antanasijevic, Aleksandar, de Gast, Marlon, Allen, Joel D., Bijl, Tom P. L., Yasmeen, Anila, Ravichandran, Rashmi, Burger, Judith A., Ozorowski, Gabriel, Torres, Jonathan L., LaBranche, Celia, Montefiori, David C., Ringe, Rajesh P., van Gils, Marit J., Moore, John P., Klasse, Per Johan, Crispin, Max, King, Neil P., Ward, Andrew B., Sanders, Rogier W.
Published in npj vaccines (09.02.2021)
Published in npj vaccines (09.02.2021)
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Animal models for microbicide studies
Veazey, Ronald S, Shattock, Robin J, Klasse, Per Johan, Moore, John P
Published in Current HIV research (01.01.2012)
Published in Current HIV research (01.01.2012)
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Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
Huang, Jinghe, Kang, Byong H., Pancera, Marie, Lee, Jeong Hyun, Tong, Tommy, Feng, Yu, Imamichi, Hiromi, Georgiev, Ivelin S., Chuang, Gwo-Yu, Druz, Aliaksandr, Doria-Rose, Nicole A., Laub, Leo, Sliepen, Kwinten, van Gils, Marit J., de la Peña, Alba Torrents, Derking, Ronald, Klasse, Per-Johan, Migueles, Stephen A., Bailer, Robert T., Alam, Munir, Pugach, Pavel, Haynes, Barton F., Wyatt, Richard T., Sanders, Rogier W., Binley, James M., Ward, Andrew B., Mascola, John R., Kwong, Peter D., Connors, Mark
Published in Nature (London) (06.11.2014)
Published in Nature (London) (06.11.2014)
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Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Kong, Leopold, Lee, Jeong Hyun, Doores, Katie J, Murin, Charles D, Julien, Jean-Philippe, McBride, Ryan, Liu, Yan, Marozsan, Andre, Cupo, Albert, Klasse, Per-Johan, Hoffenberg, Simon, Caulfield, Michael, King, C Richter, Hua, Yuanzi, Le, Khoa M, Khayat, Reza, Deller, Marc C, Clayton, Thomas, Tien, Henry, Feizi, Ten, Sanders, Rogier W, Paulson, James C, Moore, John P, Stanfield, Robyn L, Burton, Dennis R, Ward, Andrew B, Wilson, Ian A
Published in Nature structural & molecular biology (01.07.2013)
Published in Nature structural & molecular biology (01.07.2013)
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Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
Medina-Ramírez, Max, Garces, Fernando, Escolano, Amelia, Skog, Patrick, de Taeye, Steven W, Del Moral-Sanchez, Ivan, McGuire, Andrew T, Yasmeen, Anila, Behrens, Anna-Janina, Ozorowski, Gabriel, van den Kerkhof, Tom L G M, Freund, Natalia T, Dosenovic, Pia, Hua, Yuanzi, Gitlin, Alexander D, Cupo, Albert, van der Woude, Patricia, Golabek, Michael, Sliepen, Kwinten, Blane, Tanya, Kootstra, Neeltje, van Breemen, Mariëlle J, Pritchard, Laura K, Stanfield, Robyn L, Crispin, Max, Ward, Andrew B, Stamatatos, Leonidas, Klasse, Per Johan, Moore, John P, Nemazee, David, Nussenzweig, Michel C, Wilson, Ian A, Sanders, Rogier W
Published in The Journal of experimental medicine (04.09.2017)
Published in The Journal of experimental medicine (04.09.2017)
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Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
Julien, Jean-Philippe, Lee, Jeong Hyun, Cupo, Albert, Murin, Charles D., Derking, Ronald, Hoffenberg, Simon, Caulfield, Michael J., King, C. Richter, Marozsan, Andre J., Klasse, Per Johan, Sanders, Rogier W., Moore, John P., Wilson, Ian A., Ward, Andrew B.
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2013)
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Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation
Ringe, Rajesh P., Sanders, Rogier W., Yasmeen, Anila, Kim, Helen J., Lee, Jeong Hyun, Cupo, Albert, Korzun, Jacob, Derking, Ronald, van Montfort, Thijs, Julien, Jean-Philippe, Wilson, Ian A., Klasse, Per Johan, Ward, Andrew B., Moore, John P.
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
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Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody
Burton, Dennis R, Hessell, Ann J, Keele, Brandon F, Klasse, Per Johan, Ketas, Thomas A, Moldt, Brian, Dunlop, D. Cameron, Poignard, Pascal, Doyle, Lara A, Cavacini, Lisa, Veazey, Ronald S, Moore, John P
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
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Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers
Horne, W. Seth, Johnson, Lisa M, Ketas, Thomas J, Klasse, Per Johan, Lu, Min, Moore, John P, Gellman, Samuel H
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.2009)
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Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens
Antanasijevic, Aleksandar, Ueda, George, Brouwer, Philip J M, Copps, Jeffrey, Huang, Deli, Allen, Joel D, Cottrell, Christopher A, Yasmeen, Anila, Sewall, Leigh M, Bontjer, Ilja, Ketas, Thomas J, Turner, Hannah L, Berndsen, Zachary T, Montefiori, David C, Klasse, Per Johan, Crispin, Max, Nemazee, David, Moore, John P, Sanders, Rogier W, King, Neil P, Baker, David, Ward, Andrew B
Published in PLoS pathogens (11.08.2020)
Published in PLoS pathogens (11.08.2020)
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Structural Characterization of Cleaved, Soluble HIV-1 Envelope Glycoprotein Trimers
Khayat, Reza, Lee, Jeong Hyun, Julien, Jean-Philippe, Cupo, Albert, Klasse, Per Johan, Sanders, Rogier W, Moore, John P, Wilson, Ian A, Ward, Andrew B
Published in Journal of Virology (01.09.2013)
Published in Journal of Virology (01.09.2013)
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Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures
Harris, Audray, Borgnia, Mario J, Shi, Dan, Bartesaghi, Alberto, He, Haifeng, Pejchal, Robert, Kang, Yun (Kenneth), Depetris, Rafael, Marozsan, Andre J, Sanders, Rogier W, Klasse, Per Johan, Milne, Jacqueline L.S, Wilson, Ian A, Olson, William C, Moore, John P, Subramaniam, Sriram
Published in Proceedings of the National Academy of Sciences - PNAS (12.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (12.07.2011)
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Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein
Klasse, Per Johan, Depetris, Rafael S, Pejchal, Robert, Julien, Jean-Philippe, Khayat, Reza, Lee, Jeong Hyun, Marozsan, Andre J, Cupo, Albert, Cocco, Nicolette, Korzun, Jacob, Yasmeen, Anila, Ward, Andrew B, Wilson, Ian A, Sanders, Rogier W, Moore, John P
Published in Journal of Virology (01.09.2013)
Published in Journal of Virology (01.09.2013)
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