Different stages of rheumatoid arthritis: features of the synovium in the preclinical phase
van de Sande, M G H, de Hair, M J H, van der Leij, C, Klarenbeek, P L, Bos, W H, Smith, M D, Maas, M, de Vries, N, van Schaardenburg, D, Dijkmans, B A C, Gerlag, D M, Tak, P P
Published in Annals of the rheumatic diseases (01.05.2011)
Published in Annals of the rheumatic diseases (01.05.2011)
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Journal Article
Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease
Klarenbeek, P L, de Hair, M J H, Doorenspleet, M E, van Schaik, B D C, Esveldt, R E E, van de Sande, M G H, Cantaert, T, Gerlag, D M, Baeten, D, van Kampen, A H C, Baas, F, Tak, P P, de Vries, N
Published in Annals of the rheumatic diseases (01.06.2012)
Published in Annals of the rheumatic diseases (01.06.2012)
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Journal Article
IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study
Al-Soudi, A, Doorenspleet, M E, Esveldt, R E, Burgemeister, L T, Hak, A E, van den Born, B J H, Tas, S W, van Vollenhoven, R F, Klarenbeek, P L, de Vries, N
Published in Arthritis research & therapy (31.01.2019)
Published in Arthritis research & therapy (31.01.2019)
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Journal Article
Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years
Klarenbeek, P L, Remmerswaal, E B M, ten Berge, I J M, Doorenspleet, M E, van Schaik, B D C, Esveldt, R E E, Koch, S D, ten Brinke, A, van Kampen, A H C, Bemelman, F J, Tak, P P, Baas, F, de Vries, N, van Lier, R A W
Published in PLoS pathogens (01.09.2012)
Published in PLoS pathogens (01.09.2012)
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Journal Article
Enhanced gene transfer to arthritic joints using adeno-associated virus type 5: implications for intra-articular gene therapy
Adriaansen, J, Tas, S W, Klarenbeek, P L, Bakker, A C, Apparailly, F, Firestein, G S, Jorgensen, C, Vervoordeldonk, M J B M, Tak, P P
Published in Annals of the rheumatic diseases (01.12.2005)
Published in Annals of the rheumatic diseases (01.12.2005)
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Journal Article
Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity
Doorenspleet, M E, Klarenbeek, P L, de Hair, M J H, van Schaik, B D C, Esveldt, R E E, van Kampen, A H C, Gerlag, D M, Musters, A, Baas, F, Tak, P P, de Vries, N
Published in Annals of the rheumatic diseases (01.04.2014)
Published in Annals of the rheumatic diseases (01.04.2014)
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Journal Article
Intestinal CD8+ T cell responses are abundantly induced early in human development but show impaired cytotoxic effector capacities
Schreurs, R. R. C. E., Sagebiel, A. F., Steinert, F. L., Highton, A. J., Klarenbeek, P. L., Drewniak, A., Bakx, R., The, S. M. L., Ribeiro, C. M. S., Perez, D., Reinshagen, K., Geijtenbeek, T. B. H., van Goudoever, J. B., Bunders, M. J.
Published in Mucosal immunology (01.05.2021)
Published in Mucosal immunology (01.05.2021)
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Journal Article
B‐cell and T‐cell receptor repertoire in chronic inflammatory demyelinating polyneuropathy, a prospective cohort study
Lieverloo, G. G. A., Al‐Soudi, A., Wieske, L., Klarenbeek, P. L., Anang, D. C., Adrichem, M. E., Niewold, I., Schaik, B. D. C., Kampen, A. H. C., Schaik, I. N., Vries, N., Eftimov, F.
Published in Journal of the peripheral nervous system (01.03.2023)
Published in Journal of the peripheral nervous system (01.03.2023)
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P075 Targeting NF-ΚB signalling in B cells: a potential new treatment modality for anca-associated vasculitis
Van Hamburg, JP, Tuijnenburg, P, Helder, B, van Keep, LS, Rutten, LA, Wesenhagen, K, Kucharzewska, P, Jansen, MH, Al-Soudi, A, Klarenbeek, PL, Olsson, HK, de Vries, N, Kuijpers, TW, Tas, SW
Published in Annals of the rheumatic diseases (01.03.2019)
Published in Annals of the rheumatic diseases (01.03.2019)
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Journal Article
The BLIMP-1 risk allele is associated with increased synovial inflammation in rheumatoid arthritis
Herenius, M M J, van Baarsen, L G M, Klarenbeek, P L, Wijbrandts, C A, Canete, J D, Plenge, R M, Tak, P P, de Vries, N
Published in Annals of the rheumatic diseases (01.03.2011)
Published in Annals of the rheumatic diseases (01.03.2011)
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Journal Article
T- and B cell clones circulate between synovial tissue and lymph node in early stages of rheumatoid arthritis (RA): elucidating the role of lymph nodes in RA
Klarenbeek, P L, de Hair, M J, Doorenspleet, M E, Alivernini, S, van Schaik, B D C, van de Sande, M G, Berger, F H, van Kampen, A H C, Gerlag, D M, Baas, F, Tak, P P, de Vries, N
Published in Annals of the rheumatic diseases (01.03.2011)
Published in Annals of the rheumatic diseases (01.03.2011)
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Journal Article
In rheumatoid arthritis highly expanded B cell clones can be found in the early synovitis stage
Doorenspleet, M E, de Hair, M J, Herenius, M M, Klarenbeek, P L, Wijbrandts, C A, van de Sande, M G, van Schaik, B D, Esveldt, R E, Singh, J K, van Kampen, A H, Gerlag, D M, Baas, F, Tak, P P, de Vries, N
Published in Annals of the rheumatic diseases (01.03.2011)
Published in Annals of the rheumatic diseases (01.03.2011)
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Journal Article
The T cell receptor repertoire in synovial tissue of patients with early rheumatoid arthritis (RA) is dominated by highly expanded clones, which is not the case in established RA
Klarenbeek, P L, Doorenspleet, M E, de Hair, M J, Herenius, M M, van Schaik, B D C, Wijbrandts, C A, van de Sande, M G, Esveldt, R E, van Kampen, A H C, Baas, F, Tak, P P, de Vries, N
Published in Annals of the rheumatic diseases (01.03.2011)
Published in Annals of the rheumatic diseases (01.03.2011)
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Journal Article
Complete T and B cell receptor repertoire analysis in rheumatoid arthritis using high throughput sequencing
Klarenbeek, P L, Doorenspleet, M E, van Schaik, B D C, Herenius, M M, Jakobs, M E, Cantaert, T, Baeten, D L P, van Kampen, A H C, Baas, F, Tak, P P, de Vries, N
Published in Annals of the rheumatic diseases (01.03.2010)
Published in Annals of the rheumatic diseases (01.03.2010)
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Journal Article
High throughput sequencing (HTS) provides full repertoire analysis of the B and T cell receptors in humans and mice, both in blood and synovial tissue
Klarenbeek, P L, Tak, P P, Doorenspleet, M E, van Schaik, B D C, Wensveen, F M, Gottschal, L, Jakobs, M E, Derks, I A M, Eldering, E, van Kampen, A H C, Baas, F, de Vries, N
Published in Annals of the rheumatic diseases (01.03.2010)
Published in Annals of the rheumatic diseases (01.03.2010)
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Journal Article
Disruption of dominant B cell/plasma cell clones in rheumatoid arthritis synovium by rituximab correlates with treatment response
Doorenspleet, ME, Klarenbeek, PL, Boumans, MJ, Thurlings, RM, Esveldt, RE, van Schaik, BD, van Kampen, AH, Gerlag, DM, Baas, F, Tak, PP, Plenge, RM, de Vries, N
Published in Annals of the rheumatic diseases (01.02.2012)
Published in Annals of the rheumatic diseases (01.02.2012)
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Journal Article
Identification of HIV-1-specific regulatory T cells using HLA-class-II tetramers
Angin, M, Klarenbeek, PL, King, M, Wucherpfennig, KW, Addo, MM
Published in Retrovirology (13.09.2012)
Published in Retrovirology (13.09.2012)
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Journal Article
Expanded memory CD4+ T Cells in the fetal and the infant Gut; a mucosal route for mother-to-child transmission of HIV-1
Bunders, MJ, van der Loos, C, Klarenbeek, PL, van Hamme, J, Wilde, J, de Vries, N, van Lier, RA, Kootstra, N, Pals, ST, Kuijpers, TW
Published in Retrovirology (13.09.2012)
Published in Retrovirology (13.09.2012)
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