Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia
Brands, Xanthe, Haak, Bastiaan W, Klarenbeek, Augustijn M, Otto, Natasja A, Faber, Daniël R, Lutter, René, Scicluna, Brendon P, Wiersinga, W Joost, van der Poll, Tom
Published in Frontiers in immunology (06.05.2020)
Published in Frontiers in immunology (06.05.2020)
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The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis
Khan, Hina N, Brands, Xanthe, Aufiero, Simona, Hoogendijk, Arie J, Klarenbeek, Augustijn M, van Engelen, Tjitske S R, Haak, Bastiaan W, van Vught, Lonneke A, Horn, Janneke, Schultz, Marcus J, Zwinderman, Aeilko H, van der Poll, Tom, Scicluna, Brendon P
Published in Critical care (London, England) (13.07.2020)
Published in Critical care (London, England) (13.07.2020)
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An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration
Brands, Xanthe, Haak, Bastiaan W, Klarenbeek, Augustijn M, Butler, Joe, Uhel, Fabrice, Qin, Wanhai, Otto, Natasja A, Jakobs, Marja E, Faber, Daniël R, Lutter, René, Wiersinga, W Joost, van der Poll, Tom, Scicluna, Brendon P
Published in Genome medicine (16.08.2021)
Published in Genome medicine (16.08.2021)
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Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia
Schuurman, Alex R., Butler, Joe M., Michels, Erik H.A., Otto, Natasja A., Brands, Xanthe, Haak, Bastiaan W., Uhel, Fabrice, Klarenbeek, Augustijn M., Faber, Daniël R., Schomakers, Bauke V., van Weeghel, Michel, de Vos, Alex F., Scicluna, Brendon P., Houtkooper, Riekelt H., Wiersinga, W. Joost, van der Poll, Tom
Published in iScience (21.07.2023)
Published in iScience (21.07.2023)
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Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalization
Kullberg, Robert F.J., Brands, Xanthe, Klarenbeek, Augustijn M., Butler, Joe M., Otto, Natasja A., Faber, Daniël R., Scicluna, Brendon P., van der Poll, Tom, Wiersinga, W. Joost, Haak, Bastiaan W.
Published in iScience (19.08.2022)
Published in iScience (19.08.2022)
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Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia
Brands, Xanthe, Haak, Bastiaan W, Klarenbeek, Augustijn M, Otto, Natasja A, Faber, Daniël R, Lutter, René, Scicluna, Brendon P, Wiersinga, W Joost, van der Poll, Tom
Published in Frontiers in immunology (2020)
Published in Frontiers in immunology (2020)
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Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia
Michels, Erik H A, Appelman, Brent, de Brabander, Justin, van Amstel, Rombout B E, van Linge, Christine C A, Chouchane, Osoul, Reijnders, Tom D Y, Schuurman, Alex R, Sulzer, Titia A L, Klarenbeek, Augustijn M, Douma, Renée A, Bos, Lieuwe D J, Wiersinga, W Joost, Peters-Sengers, Hessel, van der Poll, Tom
Published in American journal of respiratory and critical care medicine (15.02.2024)
Published in American journal of respiratory and critical care medicine (15.02.2024)
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Human alveolar macrophages do not rely on glucose metabolism upon activation by lipopolysaccharide
Pereverzeva, Liza, van Linge, Christine C.A., Schuurman, Alex R., Klarenbeek, Augustijn M., Ramirez Moral, Ivan, Otto, Natasja A., Peters-Sengers, Hessel, Butler, Joe M., Schomakers, Bauke V., van Weeghel, Michel, Houtkooper, Riekelt H., Wiersinga, W. Joost, Bonta, Peter I., Annema, Jouke T., de Vos, Alex F., van der Poll, Tom
Published in Biochimica et biophysica acta. Molecular basis of disease (01.10.2022)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.10.2022)
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Intracellular pyruvate levels positively correlate with cytokine production capacity in tolerant monocytes from patients with pneumonia
Otto, Natasja A., Butler, Joe M., Schuurman, Alex R., Brands, Xanthe, Haak, Bastiaan W., Klarenbeek, Augustijn M., van Weeghel, Michel, Houtkooper, Riekelt H., Jakobs, Marja E., Faber, Daniël R., de Vos, Alex F., Wiersinga, W. Joost, Scicluna, Brendon P., van der Poll, Tom
Published in Biochimica et biophysica acta. Molecular basis of disease (01.11.2022)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.11.2022)
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Association of Hyperferritinemia With Distinct Host Response Aberrations in Patients With Community-Acquired Pneumonia
Brands, Xanthe, van Engelen, Tjitske S R, de Vries, Floris M C, Haak, Bastiaan W, Klarenbeek, Augustijn M, Kanglie, Maadrika M N P, van den Berk, Inge A H, Schuurman, Alex R, Peters-Sengers, Hessel, Otto, Natasja A, Faber, Daniël R, Lutter, René, Scicluna, Brendon P, Stoker, Jaap, Prins, Jan M, Joost Wiersinga, W, van der Poll, Tom
Published in The Journal of infectious diseases (01.06.2022)
Published in The Journal of infectious diseases (01.06.2022)
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Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis upon ICU Admission
Scicluna, Brendon P, Wiewel, Maryse A, van Vught, Lonneke A, Hoogendijk, Arie J, Klarenbeek, Augustijn M, Franitza, Marek, Toliat, Mohammad R, Nürnberg, Peter, Horn, Janneke, Bonten, Marc J, Schultz, Marcus J, Cremer, Olaf L, van der Poll, Tom
Published in American journal of respiratory and critical care medicine (15.04.2018)
Published in American journal of respiratory and critical care medicine (15.04.2018)
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Journal Article
Thrombocytopenia is associated with a dysregulated host response in severe COVID-19
Appelman, Brent, Michels, Erik H.A., de Brabander, Justin, Peters-Sengers, Hessel, van Amstel, Rombout B.E., Noordzij, Sophie M., Klarenbeek, Augustijn M., van Linge, Christine C.A., Chouchane, Osoul, Schuurman, Alex R., Reijnders, Tom D.Y., Douma, Renée A., Bos, Lieuwe D.J., Wiersinga, W. Joost, van der Poll, Tom
Published in Thrombosis research (01.09.2023)
Published in Thrombosis research (01.09.2023)
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Journal Article
Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death
Léopold, Valentine, Chouchane, Osoul, Butler, Joe M., Schuurman, Alex R., Michels, Erik H.A., de Brabander, Justin, Schomakers, Bauke V., van Weeghel, Michel, Picavet-Havik, Daisy I., Grootemaat, Anita E., Douma, Renée A., Reijnders, Tom D.Y., Klarenbeek, Augustijn M., Appelman, Brent, Agtmael, Michiel van, Algera, Anne Geke, Appelman, Brent, van Baarle, Floor, Beudel, Martijn, Bogaard, Harm Jan, Bomers, Marije, Bonta, Peter, Bos, Lieuwe, Botta, Michela, de Brabander, Justin, de Bree, Godelieve, de Bruin, Sanne, Bugiani, Marianna, Bulle, Esther, Buis, David T.P., Chouchane, Osoul, Clohert, Alex, Dijkstra, Mirjam, Dongelmans, Dave A., Dujardin, Romein W.G., Elbers, Paul, Fleuren, Lucas, Geerlings, Suzanne, Geijtenbeek, Theo, Girbes, Armand, Goorhuis, Bram, Grobusch, Martin P., Hagens, Laura, Hamann, Jorg, Harris, Vanessa, Hemke, Robert, Hermans, Sabine M., Heunks, Leo, Hollmann, Markus, Horn, Janneke, Hovius, Joppe W., de Jong, Menno D., Koning, Rutger, Lim, Endry H.T., van Mourik, Niels, Nellen, Jeaninne, Nossent, Esther J., Olie, Sabine, Paulus, Frederique, Peters, Edgar, Pina-Fuentes, Dan A.I., van der Poll, Tom, Preckel, Bennedikt, Raasveld, Jorinde, Reijnders, Tom, de Rotte, Maurits C.F.J., Schinkel, Michiel, Schultz, Marcus J., Schrauwen, Femke A.P., Schuurman, Alex, Schuurmans, Jaap, Sigaloff, Kim, Slim, Marleen A., Smeele, Patrick, Smit, Marry, Stijnis, Cornelis S., Stilma, Willemke, Teunissen, Charlotte, Thoral, Patrick, Tsonas, Anissa M., Tuinman, Pieter R., van der Valk, Marc, Veelo, Denise, Volleman, Carolien, de Vries, Heder, Vught, Lonneke A., van Vugt, Michèle, Wouters, Dorien, Zwinderman, A.H., Brouwer, Matthijs C., Wiersinga, W. Joost, Vlaar, Alexander P.J., van de Beek, Diederik, Wiersinga, W. Joost, van der Wel, Nicole N., den Dunnen, Jeroen, Houtkooper, Riekelt H., van't Veer, Cornelis, van der Poll, Tom
Published in Research and practice in thrombosis and haemostasis (01.10.2023)
Published in Research and practice in thrombosis and haemostasis (01.10.2023)
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Journal Article
Age-related changes in plasma biomarkers and their association with mortality in COVID-19
Michels, Erik H A, Appelman, Brent, de Brabander, Justin, van Amstel, Rombout B E, Chouchane, Osoul, van Linge, Christine C A, Schuurman, Alex R, Reijnders, Tom D Y, Sulzer, Titia A L, Klarenbeek, Augustijn M, Douma, Renée A, Bos, Lieuwe D J, Wiersinga, W Joost, Peters-Sengers, Hessel, van der Poll, Tom, van Agtmael, Michiel, Algera, Anne Geke, Appelman, Brent, van Baarle, Floor, Beudel, Martijn, Bogaard, Harm Jan, Bomers, Marije, Bonta, Peter, Bos, Lieuwe, Botta, Michela, de Brabander, Justin, de Bree, Godelieve, de Bruin, Sanne, Bugiani, Marianna, Bulle, Esther, Buis, David T P, Chouchane, Osoul, Cloherty, Alex, Dijkstra, Mirjam, Dongelmans, Dave A, Dujardin, Romein W G, Elbers, Paul, Fleuren, Lucas, Geerlings, Suzanne, Geijtenbeek, Theo, Girbes, Armand, Goorhuis, Bram, Grobusch, Martin P, Hagens, Laura, Hamann, Jorg, Harris, Vanessa, Hemke, Robert, Hermans, Sabine M, Heunks, Leo, Hollmann, Markus, Horn, Janneke, Hovius, Joppe W, de Jong, Hanna K, de Jong, Menno D, Koning, Rutger, Lemkes, Bregje, Lim, Endry H T, van Mourik, Niels, Nellen, Jeaninne, Nossent, Esther J, Olie, Sabine, Paulus, Frederique, Peters, Edgar, Pina-Fuentes, Dan A I, van der Poll, Tom, Preckel, Bennedikt, Prins, Jan M, Raasveld, Jorinde, Reijnders, Tom, de Rotte, Maurits C F J, Schinkel, Michiel, Schultz, Marcus J, Schrauwen, Femke A P, Schuurman, Alex, Schuurmans, Jaap, Sigaloff, Kim, Slim, Marleen A, Smeele, Patrick, Smit, Marry, Stijnis, Cornelis S, Stilma, Willemke, Teunissen, Charlotte, Thoral, Patrick, Tsonas, Anissa M, Tuinman, Pieter R, van der Valk, Marc, Veelo, Denise P, Volleman, Carolien, de Vries, Heder, Vught, Lonneke A, van Vugt, Michèle, Wouters, Dorien, Zwinderman, A H Koos, Brouwer, Matthijs C, Wiersinga, W Joost, Vlaar, Alexander P J, van de Beek, Diederik
Published in The European respiratory journal (01.07.2023)
Published in The European respiratory journal (01.07.2023)
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