Imaging drugs, metabolites and biomarkers in rodent lung: a DESI MS strategy for the evaluation of drug-induced lipidosis
Dexter, Alex, Steven, Rory T., Patel, Aateka, Dailey, Lea Ann, Taylor, Adam J., Ball, Doug, Klapwijk, Jan, Forbes, Ben, Page, Clive P., Bunch, Josephine
Published in Analytical and bioanalytical chemistry (01.12.2019)
Published in Analytical and bioanalytical chemistry (01.12.2019)
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Comparison of Oral, Intranasal and Aerosol Administration of Amiodarone in Rats as a Model of Pulmonary Phospholipidosis
Patel, Aateka, Hoffman, Ewelina, Ball, Doug, Klapwijk, Jan, Steven, Rory T, Dexter, Alex, Bunch, Josephine, Baker, Daniel, Murnane, Darragh, Hutter, Victoria, Page, Clive, Dailey, Lea Ann, Forbes, Ben
Published in Pharmaceutics (17.07.2019)
Published in Pharmaceutics (17.07.2019)
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A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 1 of 2)
Hailey, James R, Maleeff, Beverly E, Thomas, Heath C, Pearse, Gail, Klapwijk, Jan C, Cristofori, Patrizia G, Berridge, Brian, Kimbrough, Carie L, Parker, George A, Morton, Daniel, Elmore, Susan, Hardisty, Jerry F, Dybdal, Noel O, Rehagen, David A, Fikes, James D, Lamb, Martin, Biddle, Kathleen, Buetow, Bernard S, Carreira, Vinicius, Nyska, Abraham, Tripathi, Niraj K, Workman, Heather C, Bienvenu, Jean-Guy, Brees, Ingrid, Turk, James R, Adler, Rick R
Published in Toxicologic pathology (01.12.2017)
Published in Toxicologic pathology (01.12.2017)
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A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 2 of 2)
Hailey, James R, Maleeff, Beverly E, Thomas, Heath C, Pearse, Gail, Klapwijk, Jan C, Cristofori, Patrizia G, Berridge, Brian, Kimbrough, Carie L, Parker, George A, Morton, Daniel, Elmore, Susan, Hardisty, Jerry F, Dybdal, Noel O, Rehagen, David A, Fikes, James D, Lamb, Martin, Biddle, Kathleen, Buetow, Bernard S, Carreira, Vinicius, Nyska, Abraham, Tripathi, Niraj K, Workman, Heather C, Bienvenu, Jean-Guy, Brees, Ingrid, Turk, James R, Adler, Rick R
Published in Toxicologic pathology (01.12.2017)
Published in Toxicologic pathology (01.12.2017)
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96 Decitabine gene modulation sensitizes human non–small cell lung cancer (NSCLC) to NY-ESO-1 TCR immunotherapy (letetresgene autoleucel; GSK3377794) in vivo
Pankov, Dmitry, Eleftheriadou, Ioanna, Domogala, Anna, Brett, Sara, Patasic, Lea, Kijewska, Magdalena, Thripp, Gary, Euesden, Jack, Klapwijk, Jan, Soor, Katrina, Damm, Miriam, Hill, Mark D, Georgouli, Mirella, Shalabi, Aiman, Britten, Cedrik
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Industry survey of approaches to examination and terminology of spontaneous changes in the heart of young rats
Keenan, Charlotte M, Hughes-Earle, Angela R, Maleeff, Beverly E, Thomas, Heath C, Adler, Rick R, Cristofori, Patrizia G, Klapwijk, Jan C
Published in Toxicologic pathology (01.10.2010)
Published in Toxicologic pathology (01.10.2010)
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Morphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis
Hoffman, Ewelina, Patel, Aateka, Ball, Doug, Klapwijk, Jan, Millar, Val, Kumar, Abhinav, Martin, Abigail, Mahendran, Rhamiya, Dailey, Lea Ann, Forbes, Ben, Hutter, Victoria
Published in Pharmaceutical research (01.12.2017)
Published in Pharmaceutical research (01.12.2017)
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Journal Article
Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses
Forbes, Ben, O'Lone, Raegan, Allen, Philippa Pribul, Cahn, Anthony, Clarke, Chris, Collinge, Mark, Dailey, Lea Ann, Donnelly, Louise E., Dybowski, Joseph, Hassall, David, Hildebrand, Deon, Jones, Rhys, Kilgour, Joanne, Klapwijk, Jan, Maier, Curtis C., McGovern, Tim, Nikula, Kristen, Parry, Joel D., Reed, Matthew D., Robinson, Ian, Tomlinson, Lindsay, Wolfreys, Alison
Published in Advanced drug delivery reviews (01.05.2014)
Published in Advanced drug delivery reviews (01.05.2014)
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1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile
Fancelli, Daniele, Moll, Jürgen, Varasi, Mario, Bravo, Rodrigo, Artico, Roberta, Berta, Daniela, Bindi, Simona, Cameron, Alexander, Candiani, Ilaria, Cappella, Paolo, Carpinelli, Patrizia, Croci, Walter, Forte, Barbara, Giorgini, Maria Laura, Klapwijk, Jan, Marsiglio, Aurelio, Pesenti, Enrico, Rocchetti, Maurizio, Roletto, Fulvia, Severino, Dino, Soncini, Chiara, Storici, Paola, Tonani, Roberto, Zugnoni, Paola, Vianello, Paola
Published in Journal of medicinal chemistry (30.11.2006)
Published in Journal of medicinal chemistry (30.11.2006)
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Journal Article
Spontaneous cardiomyopathy in young Sprague-Dawley rats: evaluation of biological and environmental variability
Chanut, Franck, Kimbrough, Carie, Hailey, Rick, Berridge, Brian, Hughes-Earle, Angela, Davies, Rhiannon, Roland, Kimberly, Stokes, Alan, Casartelli, Alessandro, York, Malcolm, Jordan, Holly, Crivellente, Federica, Cristofori, Patrizia, Thomas, Heath, Klapwijk, Jan, Adler, Rick
Published in Toxicologic pathology (01.12.2013)
Published in Toxicologic pathology (01.12.2013)
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Good Laboratory Practice Preclinical Safety Studies for GSK2696273 (MLV Vector-Based Ex Vivo Gene Therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG Mice
Carriglio, Nicola, Klapwijk, Jan, Hernandez, Raisa Jofra, Vezzoli, Michela, Chanut, Franck, Lowe, Rhiannon, Draghici, Elena, Nord, Melanie, Albertini, Paola, Cristofori, Patrizia, Richards, Jane, Staton, Hazel, Appleby, Jonathan, Aiuti, Alessandro, Sauer, Aisha V
Published in Human gene therapy. Clinical development (01.03.2017)
Published in Human gene therapy. Clinical development (01.03.2017)
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Revised guides for organ sampling and trimming in rats and mice--Part 2. A joint publication of the RITA and NACAD groups
Kittel, Birgit, Ruehl-Fehlert, Christine, Morawietz, Gerd, Klapwijk, Jan, Elwell, Michael R, Lenz, Barbara, O'Sullivan, M Gerard, Roth, Daniel R, Wadsworth, Peter F
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.07.2004)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.07.2004)
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Hyalinization of the pyloric stomach in CD-1 mice following oral (dietary) administration of the corticosteroid agonists mometasone furoate, budesonide, and flunisolide
McKevitt, Tom P, Giffen, Paul, Woodfine, Jennie A, McCawley, Sean J, Papworth, Steve A, McGill, Paul, Osborne, Jan, Beard, Paul, Williams, Tom C, Klapwijk, Jan, Lewis, David J
Published in Toxicologic pathology (01.10.2011)
Published in Toxicologic pathology (01.10.2011)
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In vivo mapping of fractional plasma volume (fpv) and endothelial transfer coefficient (Kps) in solid tumors using a macromolecular contrast agent: Correlation with histology and ultrastructure
Marzola, Pasquina, Farace, Paolo, Calderan, Laura, Crescimanno, Caterina, Lunati, Ernesto, Nicolato, Elena, Benati, Donatella, Degrassi, Anna, Terron, Andrea, Klapwijk, Jan, Pesenti, Enrico, Sbarbati, Andrea, Osculati, Francesco
Published in International journal of cancer (20.04.2003)
Published in International journal of cancer (20.04.2003)
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Journal Article
Revised guides for organ sampling and trimming in rats and mice – Part 2
Kittel, Birgit, Ruehl-Fehlert, Christine, Morawietz, Gerd, Klapwijk, Jan, Elwell, Michael R., Lenz, Barbara, O'Sullivan, M. Gerard, Roth, Daniel R., Wadsworth, Peter F.
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (2004)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (2004)
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