A Pegylated Leptin Antagonist Ameliorates CKD-Associated Cachexia in Mice
CHEUNG, Wai W, WEI DING, GUNTA, Sujana S, YONG GU, TABAKMAN, Rinat, KLAPPER, Leah N, GERTLER, Arieh, MAK, Robert H
Published in Journal of the American Society of Nephrology (01.01.2014)
Published in Journal of the American Society of Nephrology (01.01.2014)
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Journal Article
Tumor-inhibitory antibodies to HER-2/erbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2
KLAPPER, L. N, WATERMAN, H, SELA, M, YARDEN, Y
Published in Cancer research (Chicago, Ill.) (01.07.2000)
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Published in Cancer research (Chicago, Ill.) (01.07.2000)
Journal Article
Biochemical and Clinical Implications of the ErbB/HER Signaling Network of Growth Factor Receptors
Klapper, Leah N., Kirschbaum, Mark H., Seta, Michael, Yarden, Yosef
Published in Advances in Cancer Research (1999)
Published in Advances in Cancer Research (1999)
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Book Chapter
Journal Article
The ErbB-2/HER2 Oncoprotein of Human Carcinomas May Function Solely as a Shared Coreceptor for Multiple Stroma-Derived Growth Factors
Klapper, Leah N., Glathe, Stefanie, Vaisman, Nora, Hynes, Nancy E., Andrews, Glenn C., Sela, Michael, Yarden, Yosef
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.1999)
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Journal Article
177 Suppression of Gluten-Induced Enteropathy by the Copolymer Bl-7010 in NOD/DQ8 Transgenic Mice, an Animal Model of Celiac Disease (CD)
Galipeau, Heather, Wiepjes, Michelle, Jury, Jennifer, Huang, XianXi, Naftali, Esmira, Klapper, Leah N, Nisemblat, Yotam, Verdu, Elena F
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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Journal Article
Bivalence of EGF-like ligands drives the ErbB signaling network
Tzahar, Eldad, Pinkas-Kramarski, Ronit, Moyer, James D., Klapper, Leah N., Alroy, Iris, Levkowitz, Gil, Shelly, Maya, Henis, Sivan, Eisenstein, Miriam, Ratzkin, Barry J., Sela, Michael, Andrews, Glenn C., Yarden, Yosef
Published in The EMBO journal (15.08.1997)
Published in The EMBO journal (15.08.1997)
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Journal Article
A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors
KLAPPER, L. N, VAISMAN, N, HURWITZ, E, PINKAS-KRAMARSKI, R, YARDEN, Y, SELA, M
Published in Oncogene (01.05.1997)
Published in Oncogene (01.05.1997)
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Journal Article
The adjuvant activity of BAT antibody enables DNA vaccination to inhibit the progression of established autochthonous Her-2/neu carcinomas in BALB/c mice
Quaglino, Elena, Mastini, Cristina, Iezzi, Manuela, Forni, Guido, Musiani, Piero, Klapper, Leah N., Hardy, Britta, Cavallo, Federica
Published in Vaccine (09.05.2005)
Published in Vaccine (09.05.2005)
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Journal Article
The oncogenic ErbB-2/ErbB-3 heterodimer is a surrogate receptor of the epidermal growth factor and betacellulin
PINKAS-KRAMARSKI, R, LENFERINK, A. E. G, BACUS, S. S, LYASS, L, VAN DE POLL, M. L. M, KLAPPER, L. N, TZAHAR, E, SELA, M, VAN ZOELEN, E. J. J, YARDEN, Y
Published in Oncogene (12.03.1998)
Published in Oncogene (12.03.1998)
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Journal Article
c-Cbl Is a Suppressor of the Neu Oncogene
Levkowitz, Gil, Oved, Shlomo, Klapper, Leah N., Harari, Daniel, Lavi, Sara, Sela, Michael, Yarden, Yosef
Published in The Journal of biological chemistry (10.11.2000)
Published in The Journal of biological chemistry (10.11.2000)
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Journal Article
Specific inhibition of the reaction between a tumor-inhibitory antibody and the ErbB-2 receptor by a mimotope derived from a phage display library
Vaisman, Nora, Nissim, Ahuva, Klapper, Leah N, Tirosh, Boaz, Yarden, Yosef, Sela, Michael
Published in Immunology letters (01.12.2000)
Published in Immunology letters (01.12.2000)
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Journal Article
The CXCR4 Antagonist BL-8040 Efficiently Induces Apoptosis and Inhibits The Survival Of AML Cells
Tavor, Sigal, Weiss, Ido, Beider, Katia, Wald, Hanna, Eizenberg, Orly, Pereg, Yaron, Klapper, Leah, Nagler, Arnon, Peled, Amnon, Abraham, Michal
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Pharmacokinetic and efficacy study of cisplatin and paclitaxel formulated in a new injectable poly(sebacic-co-ricinoleic acid) polymer
Levy-Nissenbaum, Etgar, Khan, Wahid, Pawar, Rajendra P., Tabakman, Rinat, Naftali, Esmira, Winkler, Ilan, Kaufman, Olga, Klapper, Leah, Domb, Abraham J.
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2012)
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2012)
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Journal Article
A Novel Recombinant Fusion Protein Encoding a 20-Amino Acid Residue of the Third Extracellular (E3) Domain of CCR2 Neutralizes the Biological Activity of CCL2
Izhak, Liat, Wildbaum, Gizi, Zohar, Yaniv, Anunu, Rachel, Klapper, Leah, Elkeles, Adi, Seagal, Jane, Yefenof, Eitan, Ayalon-Soffer, Michal, Karin, Nathan
Published in The Journal of immunology (1950) (01.07.2009)
Published in The Journal of immunology (1950) (01.07.2009)
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Journal Article
BL-8040, a CXCR4 antagonist, synergizes with the FLT3 inhibitor AC220 inducing apoptosis and reducing minimal residual disease to prolong survival of AML diseased mice
Pereg, Yaron, Wald, Hanna, Eizenberg, Orly, Bulvik, Baruch, Tavor, Sigal, Beider, Katia, Nagler, Arnon, Klapper, Leah, Peled, Amnon, Abraham, Michal
Published in Clinical lymphoma, myeloma and leukemia (01.06.2015)
Published in Clinical lymphoma, myeloma and leukemia (01.06.2015)
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Journal Article
BL-1020: A novel antipsychotic drug with GABAergic activity and low catalepsy, is efficacious in a rat model of schizophrenia
Geffen, Yona, Nudelman, Abraham, Gil-Ad, Irit, Rephaeli, Ada, Huang, Mei, Savitsky, Kinneret, Klapper, Leah, Winkler, Ilan, Meltzer, Herbert Y, Weizman, Abraham
Published in European neuropsychopharmacology (01.01.2009)
Published in European neuropsychopharmacology (01.01.2009)
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Journal Article
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
Pinkas‐Kramarski, R., Soussan, L., Waterman, H., Levkowitz, G., Alroy, I., Klapper, L., Lavi, S., Seger, R., Ratzkin, B. J., Sela, M., Yarden, Y.
Published in The EMBO journal (15.05.1996)
Published in The EMBO journal (15.05.1996)
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Journal Article
Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers
Lenferink, Anne E.G., Pinkas-Kramarski, Ronit, van de Poll, Monique L.M., van Vugt, Marianne J.H., Klapper, Leah N., Tzahar, Eldad, Waterman, Hadassa, Sela, Michael, van Zoelen, Everardus J.J., Yarden, Yosef
Published in The EMBO journal (15.06.1998)
Published in The EMBO journal (15.06.1998)
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Journal Article
Coupling of the c-Cbl protooncogene product to ErbB-1/EGF-receptor but not to other ErbB proteins
Levkowitz, G, Klapper, L N, Tzahar, E, Freywald, A, Sela, M, Yarden, Y
Published in Oncogene (07.03.1996)
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Published in Oncogene (07.03.1996)
Journal Article
Inhibition of tumor growth by poly(ethylene glycol) derivatives of anti-ErbB2 antibodies
HURWITZ, E, KLAPPER, L. N, WILCHEK, M, YARDEN, Y, SELA, M
Published in Cancer Immunology, Immunotherapy (01.07.2000)
Published in Cancer Immunology, Immunotherapy (01.07.2000)
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Journal Article