A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer's disease
Shahpasand-Kroner, Hedieh, Klafki, Hans-W, Bauer, Chris, Schuchhardt, Johannes, Hüttenrauch, Melanie, Stazi, Martina, Bouter, Caroline, Wirths, Oliver, Vogelgsang, Jonathan, Wiltfang, Jens
Published in Alzheimer's research & therapy (08.12.2018)
Published in Alzheimer's research & therapy (08.12.2018)
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Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation
Klafki, Hans-W, Vogelgsang, Jonathan, Manuilova, Ekaterina, Bauer, Chris, Jethwa, Alexander, Esselmann, Hermann, Jahn-Brodmann, Anke, Osterloh, Dirk, Lachmann, Ingolf, Breitling, Benedict, Rauter, Carolin, Hansen, Niels, Bouter, Caroline, Palme, Stefan, Schuchhardt, Johannes, Wiltfang, Jens
Published in Alzheimer's research & therapy (07.09.2022)
Published in Alzheimer's research & therapy (07.09.2022)
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Development and Technical Validation of an Immunoassay for the Detection of APP669–711 (Aβ−3–40) in Biological Samples
Klafki, Hans W., Rieper, Petra, Matzen, Anja, Zampar, Silvia, Wirths, Oliver, Vogelgsang, Jonathan, Osterloh, Dirk, Rohdenburg, Lara, Oberstein, Timo J., Jahn, Olaf, Beyer, Isaak, Lachmann, Ingolf, Knölker, Hans-Joachim, Wiltfang, Jens
Published in International journal of molecular sciences (08.09.2020)
Published in International journal of molecular sciences (08.09.2020)
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Validation of a Commercial Chemiluminescence Immunoassay for the Simultaneous Measurement of Three Different Amyloid-β Peptides in Human Cerebrospinal Fluid and Application to a Clinical Cohort
Klafki, Hans-W, Hafermann, Henning, Bauer, Chris, Haussmann, Ute, Kraus, Inga, Schuchhardt, Johannes, Muck, Stephan, Scherbaum, Norbert, Wiltfang, Jens
Published in Journal of Alzheimer's disease (06.09.2016)
Published in Journal of Alzheimer's disease (06.09.2016)
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Journal Article
N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models
Wirths, Oliver, Walter, Susanne, Kraus, Inga, Klafki, Hans W., Stazi, Martina, Oberstein, Timo J., Ghiso, Jorge, Wiltfang, Jens, Bayer, Thomas A., Weggen, Sascha
Published in Alzheimer's research & therapy (04.10.2017)
Published in Alzheimer's research & therapy (04.10.2017)
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Journal Article
An Inhibitor of Tau Hyperphosphorylation Prevents Severe Motor Impairments in Tau Transgenic Mice
Le Corre, Sylvie, Klafki, Hans W., Plesnila, Nikolaus, Hübinger, Gabriele, Obermeier, Axel, Sahagún, Heidi, Monse, Barbara, Seneci, Pierfausto, Lewis, Jada, Eriksen, Jason, Zehr, Cynthia, Yue, Mei, McGowan, Eileen, Dickson, Dennis W., Hutton, Michael, Roder, Hanno M.
Published in Proceedings of the National Academy of Sciences - PNAS (20.06.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (20.06.2006)
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Micro-droplet arrays for micro-compartmentalization using an air/water interface
Kunding, Andreas H, Busk, Louise L, Webb, Helen, Klafki, Hans W, Otto, Markus, Kutter, Jörg P, Dufva, Martin
Published in Lab on a chip (01.01.2018)
Published in Lab on a chip (01.01.2018)
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Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid
Schieb, Heinke, Kratzin, Hartmut, Jahn, Olaf, Möbius, Wiebke, Rabe, Sabine, Staufenbiel, Matthias, Wiltfang, Jens, Klafki, Hans W
Published in The Journal of biological chemistry (30.09.2011)
Published in The Journal of biological chemistry (30.09.2011)
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Journal Article
Automated Capillary Electrophoresis Immunoblot for the Detection of Alpha-Synuclein in Mouse Tissue
Erdmann, Leonie, Santos, Patrícia I., Rieper, Petra, Klafki, Hans W., Beutner, Dirk, Wiltfang, Jens, Outeiro, Tiago F., Setz, Cristian
Published in Journal of Parkinson's disease (01.01.2024)
Published in Journal of Parkinson's disease (01.01.2024)
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Journal Article
Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models
Reinert, Jochim, Richard, Bernhard C, Klafki, Hans W, Friedrich, Beate, Bayer, Thomas A, Wiltfang, Jens, Kovacs, Gabor G, Ingelsson, Martin, Lannfelt, Lars, Paetau, Anders, Bergquist, Jonas, Wirths, Oliver
Published in Acta neuropathologica communications (08.03.2016)
Published in Acta neuropathologica communications (08.03.2016)
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Journal Article
method to prevent cross contamination during 2-DE by β-amyloid peptides
Schieb, Heinke, Spitzer, Philipp, Riess, Verena, Wiltfang, Jens, Klafki, Hans W
Published in Proteomics (Weinheim) (01.10.2010)
Published in Proteomics (Weinheim) (01.10.2010)
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Profiling Of Membrane-anchored β-secretase Inhibitors In Cell Cultures
Schieb, Heinke, Knölker, Hans-Joachim, Weidlich, Sebastian, Wiltfang, Jens, Klafki, Hans W
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
Inhibition of PHF-like Tau Hyperphosphorylation in SH-SY5Y Cells and Rat Brain Slices by K252a
Hübinger, Gabriele, Geis, Silvia, LeCorre, Sylvie, Mühlbacher, Susanne, Gordon, Sandra, Fracasso, R. Paul, Hoffman, Fred, Ferrand, Sandrine, Klafki, Hans W., Roder, Hanno M.
Published in Journal of Alzheimer's disease (01.04.2008)
Published in Journal of Alzheimer's disease (01.04.2008)
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Journal Article
Electrophoretic Separation of βA4 Peptides (1–40) and (1–42)
Klafki, Hans-W., Wiltfang, Jens, Staufenbiel, Matthias
Published in Analytical biochemistry (15.05.1996)
Published in Analytical biochemistry (15.05.1996)
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Journal Article
P1-071: High resolution 1d and 2d analysis of A-beta peptides in plasma, Csf and brains of APP23 transgenic mice
Klafki, Hans W, Schieb, Heinke, Paul, Sabine, Esselmann, Hermann, Leuthäusser, Sabine, Maler, Juan Manuel, Bibl, Mirko, Staufenbiel, Matthias, Wiltfang, Jens
Published in Alzheimer's & dementia (01.07.2008)
Published in Alzheimer's & dementia (01.07.2008)
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Micro-droplet arrays for micro-compartmentalization using an air/water interfaceElectronic supplementary information (ESI) available. See DOI: 10.1039/c8lc00608c
Kunding, Andreas H, Busk, Louise L, Webb, Helen, Klafki, Hans W, Otto, Markus, Kutter, Jörg P, Dufva, Martin
Year of Publication 11.09.2018
Year of Publication 11.09.2018
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Journal Article
Calpain inhibitor I decreases βA4 secretion from human embryonal kidney cells expressing β-amyloid precursor protein carrying the APP670/671 double mutation
Klafki, Hans-W., Paganetti, Paolo A., Sommer, Bernd, Staufenbiel, Matthias
Published in Neuroscience letters (01.12.1995)
Published in Neuroscience letters (01.12.1995)
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Journal Article
Deposition of C-terminally truncated A beta species A beta 37 and A beta 39 in Alzheimer's disease and transgenic mouse models
Reinert, Jochim, Richard, Bernhard C., Klafki, Hans W., Friedrich, Beate, Bayer, Thomas A., Wiltfang, Jens, Kovacs, Gabor G., Ingelsson, Martin, Lannfelt, Lars, Paetau, Anders, Bergquist, Jonas, Wirths, Oliver
Published in Acta neuropathologica communications (08.03.2016)
Published in Acta neuropathologica communications (08.03.2016)
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