The Integrin Adaptor Kindlin-3 Is a Gatekeeper for Germinal Center Responses and the Development of Chronic Lymphocytic Leukemia
Li, Lixia, Härzschel, Andrea, Krenn, Peter, Danner, Danielle-Justine, Polcik, Laura, Fernández-Rego, Adrián, Schönbeck, Jennifer, Riedle, Melissa, Kissel, Sandra, Miething, Cornelius, Duyster, Justus, Koehler, Natalie, Fagerholm, Susanna, Carrasco, Yolanda, Maity, Palash, Hartmann, Tanja Nicole
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms
Jaeger, Amelie, Gambheer, Sudheer Madan Mohan, Sun, Xiaoyang, Chernyakov, Dmitry, Skorobohatko, Oleksandra, Mack, Thomas, Kissel, Sandra, Pfeifer, Dietmar, Zeiser, Robert, Fisch, Paul, Andrieux, Geoffroy, Bräuer-Hartmann, Daniela, Bauer, Marcus, Schulze, Susann, Follo, Marie, Boerries, Melanie, von Bubnoff, Nikolas, Miething, Cornelius, Hidalgo, Jose Villacorta, Klein, Claudius, Weber, Thomas, Wickenhauser, Claudia, Binder, Mascha, Dierks, Christine
Published in Blood (08.06.2023)
Published in Blood (08.06.2023)
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The Pan-PIM Kinase Inhibitor LGB321 Strongly Increases Ibrutinib Effects in CLL, By Blocking Anti-Apoptotic Pathways and Microenvironmental Interactions
Decker, Sarah, Saleem, Shifa, Kissel, Sandra, Zwick, Anabel, Aumann, Konrad, Zirlik, Katja, Duyster, Justus, Dierks, Christine
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Establishment and Characterization of Mouse Models with Primary and Acquired BTK Inhibitor Resistance
Polcik, Laura, Dannewitz Prosseda, Svenja, Underbayev, Chingiz, Andrieux, Geoffroy, Li, Lixia, Danner, Danielle-Justine, Ashok, Driti, Kissel, Sandra, Parsa, Sara, Koehler, Natalie, Börries, Melanie, Duyster, Justus, Bibikova, Elena, Wiestner, Adrian, Hartmann, Tanja Nicole
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Optimized Xenograft Protocol for Chronic Lymphocytic Leukemia Results in High Engraftment Efficiency for All CLL Subgroups
Decker, Sarah, Zwick, Anabel, Khaja Saleem, Shifa, Kissel, Sandra, Rettig, Andres, Aumann, Konrad, Dierks, Christine
Published in International journal of molecular sciences (12.12.2019)
Published in International journal of molecular sciences (12.12.2019)
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CD49d Shapes B Cell Receptor Responsiveness and Tissue Distribution in an Aggressive Chronic Lymphocytic Leukemia Murine Model
Polcik, Laura, Danner, Danielle-Justine, Bomben, Riccardo, Bittolo, Tamara, Li, Lixia, Ashok, Driti, Kissel, Sandra, Koehler, Natalie, Härzschel, Andrea, Andrieux, Geoffroy, Boerries, Melanie, Engel, Sophia, Haslauer, Theresa, Hoepner, Jan, Zaborsky, Nadja, Greil, Richard, Miething, Cornelius, Shoumariyeh, Khalid, Duque Afonso, Jesus, Duyster, Justus, Zucchetto, Antonella, Gattei, Valter, Hartmann, Tanja Nicole
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling
Rückert, Tamina, Andrieux, Geoffroy, Boerries, Melanie, Hanke-Müller, Kathrin, Woessner, Nadine M, Doetsch, Stephanie, Schell, Christoph, Aumann, Konrad, Kolter, Julia, Schmitt-Graeff, Annette, Schiff, Marcel, Braun, Lukas M, Haring, Eileen, Kissel, Sandra, Siranosian, Benjamin A, Bhatt, Ami S, Nordkild, Peter, Wehkamp, Jan, Jensen, Benjamin A H, Minguet, Susana, Duyster, Justus, Zeiser, Robert, Köhler, Natalie
Published in Science translational medicine (21.12.2022)
Published in Science translational medicine (21.12.2022)
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The Pan-PIM Kinase Inhibitor LGB321 Affects Apoptotic Pathways and Microenvironmental Interactions in CLL
Decker, Sarah, Kissel, Sandra, Aumann, Konrad, Zenz, Thorsten, Zirlik, Katja, Claus, Rainer, Duyster, Justus, Dierks, Christine
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1)
Decker, Sarah, Finter, Johannes, Forde, Aaron James, Kissel, Sandra, Schwaller, Juerg, Mack, Thomas Sebastian, Kuhn, Anabel, Gray, Nathanael, Follo, Marie, Jumaa, Hassan, Burger, Meike, Zirlik, Katja, Pfeifer, Dietmar, Miduturu, Chandrasekhar V, Eibel, Hermann, Veelken, Hendrik, Dierks, Christine
Published in Molecular cancer therapeutics (01.05.2014)
Published in Molecular cancer therapeutics (01.05.2014)
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Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression
Klein, Claudius, Zwick, Anabel, Kissel, Sandra, Forster, Christine Ulrike, Pfeifer, Dietmar, Follo, Marie, Illert, Anna Lena, Decker, Sarah, Benkler, Thomas, Pahl, Heike, Oostendorp, Robert A J, Aumann, Konrad, Duyster, Justus, Dierks, Christine
Published in The Journal of experimental medicine (08.02.2016)
Published in The Journal of experimental medicine (08.02.2016)
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TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia
Szenes, Eva, Härzschel, Andrea, Decker, Sarah, Tissino, Erika, Pischeli, Justine, Gutjahr, Julia Christine, Kissel, Sandra, Pennisi, Sandra, Höpner, Jan Philip, Egle, Alexander, Zaborsky, Nadja, Dierks, Christine, Follo, Marie, Chigaev, Alexandre, Zucchetto, Antonella, Greil, Richard, Gattei, Valter, Hartmann, Tanja Nicole
Published in Leukemia (01.09.2020)
Published in Leukemia (01.09.2020)
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PIM1 inhibition effectively enhances plerixafor-induced HSC mobilization by counteracting CXCR4 upregulation and blocking CXCL12 secretion
Müller, Tony Andreas, Pennisi, Sandra, Zwick, Anabel, Decker, Sarah, Klein, Claudius, Rister, Benjamin, Rudorf, Alina, Kissel, Sandra, Follo, Marie, Wäsch, Ralph, Illert, Anna Lena, Pfeifer, Dietmar, Oostendorp, Robert, Waskow, Claudia, Dierks, Christine, Duyster, Justus
Published in Leukemia (01.05.2019)
Published in Leukemia (01.05.2019)
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Journal Article
PIM1 Inhibition Enhances and Prolongs Plerixafor-Induced Mobilization of HSCs
Müller, Tony Andreas, Zwick, Anabel, Decker, Sarah, Klein, Claudius, Rister, Benjamin, Rudorf, Alina, Kissel, Sandra, Follo, Marie, Wäsch, Ralph, Illert, Anna Lena, Waskow, Claudia, Dierks, Christine, Duyster, Justus
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Depletion of Ptch2 Activates Canonical and Non-Canonical HH Signaling within the Niche Leading to Myeloproliferation, Stem Cell Exhaustion and Accelerates JAK2V617F Driven Disease
Klein, Claudius, Kuhn, Anabel, Kissel, Sandra, Follo, Marie, Illert, Anna Lena, Pfeifer, Dietmar, Pahl, Heike L, Oostendorp, Robert A.J., Duyster, Justus, Dierks, Christine
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression
Klein, Claudius, Zwick, Anabel, Kissel, Sandra, Forster, Christine Ulrike, Pfeifer, Dietmar, Follo, Marie, Illert, Anna Lena, Decker, Sarah, Benkler, Thomas, Pahl, Heike, Oostendorp, Robert A.J., Aumann, Konrad, Duyster, Justus, Dierks, Christine
Published in The Journal of cell biology (15.02.2016)
Published in The Journal of cell biology (15.02.2016)
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Journal Article
Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression
Klein, Claudius, Zwick, Anabel, Kissel, Sandra, Forster, Christine Ulrike, Pfeifer, Dietmar, Follo, Marie, Illert, Anna Lena, Decker, Sarah, Benkler, Thomas, Pahl, Heike, Oostendorp, Robert A.J., Aumann, Konrad, Duyster, Justus, Dierks, Christine
Published in The Journal of cell biology (01.02.2016)
Published in The Journal of cell biology (01.02.2016)
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