Epac2-Rap1 Signaling Regulates Reactive Oxygen Species Production and Susceptibility to Cardiac Arrhythmias
Yang, Zhaokang, Kirton, Hannah M, Al-Owais, Moza, Thireau, Jérôme, Richard, Sylvain, Peers, Chris, Steele, Derek S
Published in Antioxidants & redox signaling (20.07.2017)
Published in Antioxidants & redox signaling (20.07.2017)
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Flecainide induces a sustained countercurrent dependent effect on RyR2 in permeabilized WT ventricular myocytes but not in intact cells
Steer, Emma J, Yang, Zhaokang, Al-Owais, Moza M, Kirton, Hannah M, White, Edward, Steele, Derek S
Published in Frontiers in pharmacology (12.04.2023)
Published in Frontiers in pharmacology (12.04.2023)
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Super-Resolution Analysis of the Origins of the Elementary Events of ER Calcium Release in Dorsal Root Ganglion Neurons
Hurley, Miriam E, Shah, Shihab S, Sheard, Thomas M D, Kirton, Hannah M, Steele, Derek S, Gamper, Nikita, Jayasinghe, Izzy
Published in Cells (Basel, Switzerland) (23.12.2023)
Published in Cells (Basel, Switzerland) (23.12.2023)
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A correlative super-resolution protocol to visualise structural underpinnings of fast second-messenger signalling in primary cell types
Hurley, Miriam E., Sheard, Thomas M.D., Norman, Ruth, Kirton, Hannah M., Shah, Shihab S., Pervolaraki, Eleftheria, Yang, Zhaokang, Gamper, Nikita, White, Ed, Steele, Derek, Jayasinghe, Izzy
Published in Methods (San Diego, Calif.) (01.09.2021)
Published in Methods (San Diego, Calif.) (01.09.2021)
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Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy
Sheard, Thomas M. D, Hurley, Miriam E, Colyer, John, White, Ed, Norman, Ruth, Pervolaraki, Eleftheria, Narayanasamy, Kaarjel K, Hou, Yufeng, Kirton, Hannah M, Yang, Zhaokang, Hunter, Liam, Shim, Jung-uk, Clowsley, Alexander H, Smith, Andrew J, Baddeley, David, Soeller, Christian, Colman, Michael A, Jayasinghe, Izzy
Published in ACS nano (26.02.2019)
Published in ACS nano (26.02.2019)
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A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K + channels in carbon monoxide-induced proarrhythmic early afterdepolarizations
Al-Owais, Moza M, Hettiarachchi, Nishani T, Kirton, Hannah M, Hardy, Matthew E, Boyle, John P, Scragg, Jason L, Steele, Derek S, Peers, Chris
Published in The FASEB journal (01.11.2017)
Published in The FASEB journal (01.11.2017)
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The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway
Yang, Zhaokang, Kirton, Hannah M, MacDougall, David A, Boyle, John P, Deuchars, James, Frater, Brenda, Ponnambalam, Sreenivasan, Hardy, Matthew E, White, Edward, Calaghan, Sarah C, Peers, Chris, Steele, Derek S
Published in Science signaling (13.10.2015)
Published in Science signaling (13.10.2015)
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The EPAC2 Inhibitor ESI-05 Prolongs the Action Potential and Increases Susceptibility to EAD Arrhythmias
Kirton, Hannah M., Al-Owais, Moza, Peers, Chris, Steele, Derek S.
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Journal Article
Optical Superresolution Analysis of Intracellular Calcium Handling Proteins and Correlating Calcium Signal Morphology
Hurley, Miriam E., Sheard, Thomas M., Norman, Ruth, Kirton, Hannah M., Shah, Shihab S., Pervolaraki, Eleftheria, Yang, Zhaokang, Steele, Derek S., Gamper, Nikita, White, Ed, Jayasinghe, Izzy
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
A super-resolution protocol to correlate structural underpinnings of fast second-messenger signalling in primary cell types
Hurley, Miriam E, Sheard, Thomas M D, Norman, Ruth, Kirton, Hannah M, Shah, Shihab S, Pervolaraki, Eleftheria, Yang, Zhaokang, Gamper, Nikita, White, Ed, Steele, Derek, Jayasinghe, Izzy
Published in bioRxiv (30.09.2020)
Published in bioRxiv (30.09.2020)
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