The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody
Smith, Sheena N., Schubert, Rajib, Simic, Branko, Brücher, Dominik, Schmid, Markus, Kirk, Niels, Freitag, Patrick C., Gradinaru, Viviana, Plückthun, Andreas
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2021)
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An engineered T-cell engager with selectivity for high mesothelin-expressing cells and activity in the presence of soluble mesothelin
Snell, Daniel, Gunde, Tea, Warmuth, Stefan, Chatterjee, Bithi, Brock, Matthias, Hess, Christian, Johansson, Maria, Simonin, Alexandre, Spiga, Fabio Mario, Weinert, Christopher, Kirk, Niels, Bassler, Nicole, Campos Carrascosa, Lucia, Flückiger, Naomi, Heiz, Robin, Wagen, Sandro, Giezendanner, Noreen, Alberti, Alessandra, Yaman, Yasemin, Mahler, Dana, Diem, Dania, Lichtlen, Peter, Urech, David
Published in Oncoimmunology (31.12.2023)
Published in Oncoimmunology (31.12.2023)
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1389 An assessment of ROR1 expression across tumor tissue and the investigation of a ROR1-targeted T cell engager as a therapeutic strategy to target ROR1 positive tumors
Snell, Daniel, Kirk, Niels, Bassler, Nicole, Carrascosa, Lucia Campos, Chrom, Pawel, Lichtlen, Peter, Urech, David
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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844 A trispecific ROR1 x CD3 T cell engager mediates in vitro tumor cell killing and in vivo tumor eradication
Chatterjee, Bithi, Snell, Daniel, Hess, Christian, Brock, Matthias, Spiga, Fabio, Simonin, Alexandre, Gunde, Tea, Warmuth, Stefan, Weinert, Christopher, Bassler, Nicole, Kirk, Niels, Schumacher, Nina, Mahler, Dana, Yaman, Yasemin, Bommer, Bettina, Gambino, Giorgio, Giezendanner, Noreen, Kuettner, Benjamin, Flueckiger, Naomi, Heiz, Robin, Wagen, Sandro, Diem, Dania, Zeberer, Julia, Urech, David
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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684 A low affinity bivalent mesothelin-binding MATCH4 multispecific T cell engager increases cytotoxic selectivity for high mesothelin expressing cells
Chatterjee, Bithi, Simonin, Alexandre, Snell, Daniel, Gunde, Tea, Hess, Christian, Brock, Matthias, Warmuth, Stefan, Weinert, Christopher, Kirk, Niels, Diem, Dania, Flückiger, Naomi, Heiz, Robin, Küttner, Benjamin, Mahler, Dana, Morenzoni, Diego, Wagen, Sandro, Zeberer, Julia, Urech, David
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Haematological rather than skeletal muscle adaptations contribute to the increase in peak oxygen uptake induced by moderate endurance training
Montero, David, Cathomen, Adrian, Jacobs, Robert A., Flück, Daniela, Leur, Jeroen, Keiser, Stefanie, Bonne, Thomas, Kirk, Niels, Lundby, Anne‐Kristine, Lundby, Carsten
Published in The Journal of physiology (15.10.2015)
Published in The Journal of physiology (15.10.2015)
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Twenty‐eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle
Jacobs, Robert A., Lundby, Anne‐Kristine Meinild, Fenk, Simone, Gehrig, Saskia, Siebenmann, Christoph, Flück, Daniela, Kirk, Niels, Hilty, Matthias P., Lundby, Carsten
Published in The Journal of physiology (01.03.2016)
Published in The Journal of physiology (01.03.2016)
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Journal Article
Twenty-eight days of exposure to 3,454 m increases mitochondrial volume density in human skeletal muscle
Jacobs, Robert A., Meinild Lundby, Anne-Kristine, Fenk, Simone, Gehrig, Saskia, Christoph, Siebenmann, Flück, Daniela, Kirk, Niels, Hilty, Matthias P., Lundby, Carsten
Published in The Journal of physiology (2015)
Published in The Journal of physiology (2015)
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Abstract 2870: Dose selection investigations and combination strategies of NM21-1480, a PD-L1/4-1BB/HSA trispecific MATCH3 therapeutic clinical candidate
Snell, Daniel, Gunde, Tea, Warmuth, Stefan, Lichtlen, Peter, Liu, Linlin, Teng, Shu-wen, Zhang, Lan, Pan, ChaoHsuan, Li, Peiqi, Tietz, Julia, Brock, Matthias, Simonim, Alexandre, Hess, Christian, Weinert, Christopher, Johansson, Maria, Chatterjeee, Bithi, Bassler, Nicole, Kirk, Niels, Mendes, Catia, Heiz, Robin, Flueckiger, Naomi, Diem, Dania, Mahler, Dana, Wickihalder, Belinda, Muntwiler, Simone, Wagen, Sandro, vom Baur, Elmar, Tse, Archie N., Urech, David
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 2871: NM28-2746, a reduced affinity bivalent mesothelin-binding MATCH4 T cell engager, with half-life extension, increases selectivity for killing of mesothelin-overexpressing cells
Chatterjee, Bithi, Hess, Christian, Snell, Daniel, Gunde, Tea, Warmuth, Stefan, Simonin, Alexandre, Brock, Matthias, Spiga, Fabio, Johansson, Maria, Weinert, Christopher, Tietz, Julia, Kirk, Niels, Bassler, Nicole, Mahler, Dana, Diem, Dania, Carrella, Alessandra, Giezendanner, Noreen, Alberti, Alessandra, Gambino, Giorgio, Wickihalder, Belinda, Bommer, Bettina, Muntwiler, Simone, Yaman, Yasemin, Flueckiger, Naomi, Heiz, Robin, Wagen, Sandro, Urech, David
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Muscle Activity during Functional Coordination Training: Implications for Strength Gain and Rehabilitation
Jørgensen, Marie B, Andersen, Lars L, Kirk, Niels, Pedersen, Mogens T, Søgaard, Karen, Holtermann, Andreas
Published in Journal of strength and conditioning research (01.07.2010)
Published in Journal of strength and conditioning research (01.07.2010)
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Determination of the Rate Constants k1 and k2 of the Linderstrøm-Lang Model for Protein Amide Hydrogen Exchange: A Study of the Individual Amides in Hen Egg-white Lysozyme
Pedersen, Torben Graves, Thomsen, Niels Kirk, Andersen, Kim Vilbour, Madsen, Jens Chr, Poulsen, Flemming M.
Published in Journal of molecular biology (20.03.1993)
Published in Journal of molecular biology (20.03.1993)
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Structure and interactions of NCAM modules 1 and 2, basic elements in neural cell adhesion
Poulsen, Flemming M, Jensen, Peter Holme, Soroka, Vladislav, Thomsen, Niels Kirk, Ralets, Igor, Berezin, Vladimir, Bock, Elisabeth
Published in Nature structural biology (01.05.1999)
Published in Nature structural biology (01.05.1999)
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