Aviation Decompression Sickness in Aerospace and Hyperbaric Medicine
Kutz, Craig J, Kirby, Ian J, Grover, Ian R, Tanaka, Hideaki L
Published in Aerospace medicine and human performance (01.01.2023)
Published in Aerospace medicine and human performance (01.01.2023)
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Journal Article
Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery
Lee, E-Chiang, Liang, Qi, Ali, Hanif, Bayliss, Luke, Beasley, Alastair, Bloomfield-Gerdes, Tara, Bonoli, Laura, Brown, Richard, Campbell, Jamie, Carpenter, Adam, Chalk, Sara, Davis, Alison, England, Nick, Fane-Dremucheva, Alla, Franz, Bettina, Germaschewski, Volker, Holmes, Helen, Holmes, Steve, Kirby, Ian, Kosmac, Miha, Legent, Anais, Lui, Hui, Manin, Anais, O'Leary, Siobhan, Paterson, Jemima, Sciarrillo, Rocco, Speak, Anneliese, Spensberger, Dominik, Tuffery, Laura, Waddell, Nikole, Wang, Wei, Wells, Sophie, Wong, Vivian, Wood, Andrew, Owen, Michael J, Friedrich, Glenn A, Bradley, Allan
Published in Nature biotechnology (01.04.2014)
Published in Nature biotechnology (01.04.2014)
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Journal Article
High resolution structures of HIV-1 RT from four RT-inhibitor complexes
Ren, J, Esnouf, R, Garman, E, Somers, D, Ross, C, Kirby, I, Keeling, J, Darby, G, Jones, Y, Stuart, D
Published in Nature structural biology (01.04.1995)
Published in Nature structural biology (01.04.1995)
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Identification of Contact Residues and Definition of the CAR-Binding Site of Adenovirus Type 5 Fiber Protein
Kirby, I, Davison, E, Beavil, A J, Soh, C P, Wickham, T J, Roelvink, P W, Kovesdi, I, Sutton, B J, Santis, G
Published in Journal of Virology (01.03.2000)
Published in Journal of Virology (01.03.2000)
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Mutations in the DG Loop of Adenovirus Type 5 Fiber Knob Protein Abolish High-Affinity Binding to Its Cellular Receptor CAR
Kirby, I, Davison, E, Beavil, A J, Soh, C P, Wickham, T J, Roelvink, P W, Kovesdi, I, Sutton, B J, Santis, G
Published in Journal of Virology (01.11.1999)
Published in Journal of Virology (01.11.1999)
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Adenovirus Type 9 Fiber Knob Binds to the Coxsackie B Virus-Adenovirus Receptor (CAR) with Lower Affinity than Fiber Knobs of Other CAR-Binding Adenovirus Serotypes
Kirby, I, Lord, R, Davison, E, Wickham, T J, Roelvink, P W, Kovesdi, I, Sutton, B J, Santis, G
Published in Journal of Virology (01.08.2001)
Published in Journal of Virology (01.08.2001)
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3′-Azido-3′-Deoxythymidine Drug Resistance Mutations in HIV-1 Reverse Transcriptase Can Induce Long Range Conformational Changes
Ren, Jingshan, Esnouf, Robert M., Hopkins, Andrew L., Jones, E. Yvonne, Kirby, Ian, Keeling, James, Ross, Carl K., Larder, Brendan A., Stuart, David I., Stammers, David K.
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.1998)
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Hematopoietic Stem Cells Expressing Engineered CD45 Enable a Near Universal Targeted Therapy for Hematologic Diseases
Marone, Romina, Garaudé, Simon, Lepore, Rosalba, Devaux, Anna, Beerlage, Astrid, Simonetta, Federico, Camus, Anna, Durzynska, Izabela, Kirby, Ian, Van Berkel, Patrick, Kunz, Christian, Urlinger, Stefanie, Jeker, Lukas T
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Abstract 234: Pre-clinical characterization of 3A4-PL1601, a novel pyrrolobenzodiazepine (PBD) dimer-based antibody-drug conjugate (ADC) directed against KAAG1-expressing malignancies
Zammarchi, Francesca, Bertelli, Francois, Havenith, Karin, Kirby, Ian, Chivers, Simon, Berkel, Patrick H. van
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Development of Anti-CD45 Antibody Drug Conjugates As Targeted Conditioning Agents for Transplantation/Gene Therapy with Potent Anti-Leukemic Properties
Yeung, Jenny, Liao, Aiyin, Shaw, Matthew, Caetano-Silva, Soraia, Vetharoy, Winston, Kirby, Ian, Zammarchi, Francesca, Havenith, Karin, van Berkel, Patrick H, Booth, Claire, Gaspar, H Bobby, Thrasher, Adrian J., Chester, Kerry, Amrolia, Persis J
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant
Yeung, Jenny, Liao, Aiyin, Shaw, Matthew, Silva, Soraia, Vetharoy, Winston, Rico, Diego Leon, Kirby, Ian, Zammarchi, Francesca, Havenith, Karin, de Haan, Lolke, van Berkel, Patrick H., Sebire, Neil, Ogunbiyi, Olumide K., Booth, Claire, Gaspar, H. Bobby, Thrasher, Adrian J., Chester, Kerry A., Amrolia, Persis J.
Published in Molecular therapy (05.06.2024)
Published in Molecular therapy (05.06.2024)
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Selective haematological cancer eradication with preserved haematopoiesis
Garaudé, Simon, Marone, Romina, Lepore, Rosalba, Devaux, Anna, Beerlage, Astrid, Seyres, Denis, Dell’ Aglio, Alessandro, Juskevicius, Darius, Zuin, Jessica, Burgold, Thomas, Wang, Sisi, Katta, Varun, Manquen, Garret, Li, Yichao, Larrue, Clément, Camus, Anna, Durzynska, Izabela, Wellinger, Lisa C., Kirby, Ian, Van Berkel, Patrick H., Kunz, Christian, Tamburini, Jérôme, Bertoni, Francesco, Widmer, Corinne C., Tsai, Shengdar Q., Simonetta, Federico, Urlinger, Stefanie, Jeker, Lukas T.
Published in Nature (London) (20.06.2024)
Published in Nature (London) (20.06.2024)
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Bioaccumulation and effects of dietary exposure to the alternative flame retardant, bis(2‐ethylhexyl) tetrabromophthalate (TBPH), in the Atlantic killifish, Fundulus heteroclitus
Nacci, Diane, Clark, Bryan, La Guardia, Mark J., Miller, Ken, Champlin, Denise, Kirby, Ian, Bertrand, Ashley, Jayaraman, Saro
Published in Environmental toxicology and chemistry (01.09.2018)
Published in Environmental toxicology and chemistry (01.09.2018)
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Bioaccumulation and effects of dietary exposure to the alternative flame retardant, bis(2-ethylhexyl) tetrabromophthalate (TBPH), in the Atlantic killifish, Fundulus heteroclitus: TBPH bioaccumulation and effects in killifish
Nacci, Diane, Clark, Bryan, La Guardia, Mark J., Miller, Ken, Champlin, Denise, Kirby, Ian, Bertrand, Ashley, Jayaraman, Saro
Published in Environmental toxicology and chemistry (30.05.2018)
Published in Environmental toxicology and chemistry (30.05.2018)
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Abstract 3122: Preclinical development of a novel camptothecin-based antibody-drug conjugate targeting solid tumors expressing Claudin-6
Tsang, Nicola, Veillard, Nicolas, Horsley, Elizabeth, Havenith, Karin, Janghra, Narinder, Zaitseva, Kristina, Oblette, Cecile, Kirby, Ian, Hogg, Paul W., Zammarchi, Francesca, de Haan, Lolke, van Berkel, Patrick H.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 5085: Preclinical development of NaPi2b-PL2202, a novel camptothecin-based antibody-drug conjugate targeting solid tumors expressing NaPi2b
Horsley, Elizabeth, Jabeen, Asma, Veillard, Nicolas, Havenith, Karin, Janghra, Narinder, Alves, Pedro, Oblette, Cecile, Kirby, Ian, Hogg, Paul W., Zammarchi, Francesca, de Haan, Lolke, van Berkel, Patrick
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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