A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis
Parafati, Maddalena, Kirby, R Jason, Khorasanizadeh, Sepideh, Rastinejad, Fraydoon, Malany, Siobhan
Published in Disease models & mechanisms (01.09.2018)
Published in Disease models & mechanisms (01.09.2018)
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Journal Article
Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators
Sangaralingham, S. Jeson, Whig, Kanupriya, Peddibhotla, Satyamaheshwar, Kirby, R. Jason, Sessions, Hampton E., Maloney, Patrick R., Hershberger, Paul M., Mose-Yates, Heather, Hood, Becky L., Vasile, Stefan, Pan, Shuchong, Zheng, Ye, Malany, Siobhan, Burnett, John C.
Published in Proceedings of the National Academy of Sciences - PNAS (28.12.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (28.12.2021)
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Journal Article
Discovery of small molecule antagonists of chemokine receptor CXCR6 that arrest tumor growth in SK-HEP-1 mouse xenografts as a model of hepatocellular carcinoma
Peddibhotla, Satyamaheshwar, Hershberger, Paul M., Jason Kirby, R., Sugarman, Eliot, Maloney, Patrick R., Hampton Sessions, E., Divlianska, Daniela, Morfa, Camilo J., Terry, David, Pinkerton, Anthony B., Smith, Layton H., Malany, Siobhan
Published in Bioorganic & medicinal chemistry letters (15.02.2020)
Published in Bioorganic & medicinal chemistry letters (15.02.2020)
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Pluripotent Stem Cell-Derived Hepatocytes Phenotypic Screening Reveals Small Molecules Targeting the CDK2/4-C/EBPα/DGAT2 Pathway Preventing ER-Stress Induced Lipid Accumulation
Parafati, Maddalena, Bae, Sang Hyo, Kirby, R Jason, Fitzek, Martina, Iyer, Preeti, Engkvist, Ola, Smith, David M, Malany, Siobhan
Published in International journal of molecular sciences (15.12.2020)
Published in International journal of molecular sciences (15.12.2020)
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Journal Article
The Natural Capital approach: A framework for the successful recovery of nature in estuaries
Dowdall, Lucy, Bowe, Colm, Kirby, Jason R.
Published in Ecological solutions and evidence (01.07.2022)
Published in Ecological solutions and evidence (01.07.2022)
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Journal Article
Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface
Fells, James I, Lee, Sue Chin, Fujiwara, Yuko, Norman, Derek D, Lim, Keng Gat, Tsukahara, Ryoko, Liu, Jianxiong, Patil, Renukadevi, Miller, Duane D, Kirby, R Jason, Nelson, Sandra, Seibel, William, Papoian, Ruben, Parrill, Abby L, Baker, Daniel L, Bittman, Robert, Tigyi, Gabor
Published in Molecular pharmacology (01.09.2013)
Published in Molecular pharmacology (01.09.2013)
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Journal Article
Onset of recent rapid sea-level rise in the western Atlantic Ocean
Gehrels, W. Roland, Kirby, Jason R., Prokoph, Andreas, Newnham, Rewi M., Achterberg, Eric P., Evans, Hywel, Black, Stuart, Scott, David B.
Published in Quaternary science reviews (01.10.2005)
Published in Quaternary science reviews (01.10.2005)
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Journal Article
Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif
Fells, James I., Lee, Sue Chin, Norman, Derek D., Tsukahara, Ryoko, Kirby, Jason R., Nelson, Sandra, Seibel, William, Papoian, Ruben, Patil, Renukadevi, Miller, Duane D., Parrill, Abby L., Pham, Truc‐Chi, Baker, Daniel L., Bittman, Robert, Tigyi, Gabor
Published in The FEBS journal (01.02.2014)
Published in The FEBS journal (01.02.2014)
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Journal Article
Rapid sea-level rise in the North Atlantic Ocean since the first half of the nineteenth century
Gehrels, W. Roland, Marshall, William A., Gehrels, Maria J., Larsen, Gudrún, Kirby, Jason R., Eiríksson, Jón, Heinemeier, Jan, Shimmield, Tracy
Published in Holocene (Sevenoaks) (01.11.2006)
Published in Holocene (Sevenoaks) (01.11.2006)
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Journal Article
Group 1B Phospholipase A2–Mediated Lysophospholipid Absorption Directly Contributes to Postprandial Hyperglycemia
LABONTE, Eric D, KIRBY, R. Jason, SCHILDMEYER, Nicholas M, CANNON, April M, HUGGINS, Kevin W, HUI, David Y
Published in Diabetes (New York, N.Y.) (01.04.2006)
Published in Diabetes (New York, N.Y.) (01.04.2006)
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Journal Article
Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress
Kirby, R Jason, Divlianska, Daniela B, Whig, Kanupriya, Bryan, Nadezda, Morfa, Camilo J, Koo, Ada, Nguyen, Kevin H, Maloney, Patrick, Peddibhotla, Satayamaheshwar, Sessions, E Hampton, Hershberger, Paul M, Smith, Layton H, Malany, Siobhan
Published in The Journal of pharmacology and experimental therapeutics (01.01.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2018)
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Journal Article
Assessment of drug-induced arrhythmic risk using limit cycle and autocorrelation analysis of human iPSC-cardiomyocyte contractility
Kirby, R. Jason, Qi, Feng, Phatak, Sharangdhar, Smith, Layton H., Malany, Siobhan
Published in Toxicology and applied pharmacology (15.08.2016)
Published in Toxicology and applied pharmacology (15.08.2016)
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