Elvn-001, a Next Generation ATP-Competitive ABL1 Tyrosine Kinase Inhibitor for the Treatment of Chronic Myeloid Leukemia
Gross, Stefan D, Eide, Christopher A., Burkard, Michael R, Reister Schultz, Anna, Aujay, Monette A, Kintz, Samuel, Druker, Brian J., Lyssikatos, Joseph P
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Abstract 4019: Preclinical activity of ELVN-002: A potent, selective, and irreversible HER2 and pan-HER2 mutant small molecule inhibitor for the treatment of HER2 driven malignancies
Aujay, Monette, Broad, Amanda J., Gross, Stefan D., Ren, Li, Lyssikatos, Joseph P., Kintz, Samuel, Wang, Qi, Collins, Helen
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Discovery of N-substituted-endo-3-(8-aza-bicyclo[3.2.1]oct-3-yl)-phenol and -phenyl carboxamide series of μ-opioid receptor antagonists
Jiang, Lan, Beattie, David T., Jacobsen, John R., Kintz, Samuel, Obedencio, Glenmar P., Saito, Daisuke, Stergiades, Ioanna, Vickery, Ross G., Long, Daniel D.
Published in Bioorganic & medicinal chemistry letters (01.07.2017)
Published in Bioorganic & medicinal chemistry letters (01.07.2017)
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Mitigation of Acetylcholine Esterase Activity in the 1,7-Diazacarbazole Series of Inhibitors of Checkpoint Kinase 1
Gazzard, Lewis, Williams, Karen, Chen, Huifen, Axford, Lorraine, Blackwood, Elizabeth, Burton, Brenda, Chapman, Kerry, Crackett, Peter, Drobnick, Joy, Ellwood, Charles, Epler, Jennifer, Flagella, Michael, Gancia, Emanuela, Gill, Matthew, Goodacre, Simon, Halladay, Jason, Hewitt, Joanne, Hunt, Hazel, Kintz, Samuel, Lyssikatos, Joseph, Macleod, Calum, Major, Sarah, Médard, Guillaume, Narukulla, Raman, Ramiscal, Judi, Schmidt, Stephen, Seward, Eileen, Wiesmann, Christian, Wu, Ping, Yee, Sharon, Yen, Ivana, Malek, Shiva
Published in Journal of medicinal chemistry (25.06.2015)
Published in Journal of medicinal chemistry (25.06.2015)
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A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma
Long, Daniel D., Frieman, Bryan, Hegde, Sharath S., Hill, Craig M., Jiang, Lan, Kintz, Samuel, Marquess, Daniel G., Purkey, Hans, Shaw, Jeng-Pyng, Steinfeld, Tod, Wilson, Michael S., Wrench, Kevin
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
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