A Novel Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Has in Vivo Activity and Antipsychotic-Like Effects in Rat Behavioral Models
Kinney, Gene G, O'Brien, Julie A, Lemaire, Wei, Burno, Maryann, Bickel, Denise J, Clements, Michelle K, Chen, Tsing-Bau, Wisnoski, David D, Lindsley, Craig W, Tiller, Philip R, Smith, Sheri, Jacobson, Marlene A, Sur, Cyrille, Duggan, Mark E, Pettibone, Douglas J, Conn, P Jeffrey, Williams, Jr, David L
Published in The Journal of pharmacology and experimental therapeutics (01.04.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2005)
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Metabotropic Glutamate Subtype 5 Receptors Modulate Locomotor Activity and Sensorimotor Gating in Rodents
Kinney, Gene G, Burno, Maryann, Campbell, Una C, Hernandez, Lisa M, Rodriguez, Dana, Bristow, Linda J, Conn, P Jeffrey
Published in The Journal of pharmacology and experimental therapeutics (01.07.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2003)
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OP0205 Clinical and Preclinical Assessment of The Anti-MCAM Monoclonal Antibody PRX003, A Potential Novel Treatment for Th17-Mediated Inflammatory Diseases
Koller, M., Flanagan, K., Skov, M., Goldblum, R., Griffith, S.G., Barbour, R.M., Ehsani-Chimeh, N., Marinkovich, M.P., Zago, W., Yednock, T.A., Kinney, G.G., Ness, D.
Published in Annals of the rheumatic diseases (01.06.2016)
Published in Annals of the rheumatic diseases (01.06.2016)
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The Glycine Transporter Type 1 Inhibitor N-[3-(4'-Fluorophenyl)-3-(4'-Phenylphenoxy)Propyl]Sarcosine Potentiates NMDA Receptor-Mediated Responses In Vivo and Produces an Antipsychotic Profile in Rodent Behavior
Kinney, Gene G, Sur, Cyrille, Burno, Maryann, Mallorga, Pierre J, Williams, Jacinta B, Figueroa, David J, Wittmann, Marion, Lemaire, Wei, Conn, P. Jeffrey
Published in The Journal of neuroscience (20.08.2003)
Published in The Journal of neuroscience (20.08.2003)
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Allosteric Modulation of Group III Metabotropic Glutamate Receptor 4: A Potential Approach to Parkinson's Disease Treatment
Marino, Michael J., Williams, David L., O'Brien, Julie A., Valenti, Ornella, McDonald, Terrence P., Clements, Michelle K., Wang, Ruiping, DiLella, Anthony G., Hess, J. Fred, Kinney, Gene G., Conn, P. Jeffrey
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2003)
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Discovery of Positive Allosteric Modulators for the Metabotropic Glutamate Receptor Subtype 5 from a Series of N-(1,3-Diphenyl-1H- pyrazol-5-yl)benzamides That Potentiate Receptor Function in Vivo
Lindsley, Craig W, Wisnoski, David D, Leister, William H, O'Brien, Julie A, Lemaire, Wei, Williams, David L, Burno, Maryann, Sur, Cyrille, Kinney, Gene G, Pettibone, Doug J, Tiller, Philip R, Smith, Sheri, Duggan, Mark E, Hartman, George D, Conn, P. Jeffrey, Huff, Joel R
Published in Journal of medicinal chemistry (18.11.2004)
Published in Journal of medicinal chemistry (18.11.2004)
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Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels
Gribkoff, Valentin K, Starrett, John E, Dworetzky, Steven I, Hewawasam, Piyasena, Boissard, Christopher G, Cook, Deborah A, Frantz, Stephen W, Heman, Karen, Hibbard, Jeffrey R, Huston, Kevin, Johnson, Graham, Krishnan, Bala S, Kinney, Gene G, Lombardo, Lynn A, Meanwell, Nicholas A, Molinoff, Perry B, Myers, Robert A, Moon, Sandra L, Ortiz, Astrid, Pajor, Lorraine, Pieschl, Rick L, Post-Munson, Debra J, Signor, Laura J, Srinivas, Nugehally, Taber, Matthew T, Thalody, George, Trojnacki, Joanne T, Wiener, Harvey, Yeleswaram, Krishnaswamy, Yeola, Sarita W
Published in Nature medicine (01.04.2001)
Published in Nature medicine (01.04.2001)
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(S)-N-[1-(3-Morpholin-4-ylphenyl)ethyl]-3phenylacrylamide: An orally bioavailable KCNQ2 opener with significant activity in a cortical spreading depression model of migraine
Wu, YJ, Boissard, CG, Greco, C, Gribkoff, VK, Harden, DG, He, H, L'Heureux, A, Kang, SH, Kinney, GG, Knox, RJ, Natale, J, Newton, AE, Lehtinen-Oboma, S, Sinz, MW, Sivarao, DV, Starrett, JE, Sun, LQ, Tertyshnikova, S, Thompson, MW, Weaver, D, Wong, HS, Zhang, L, Dworetzky, SL
Published in Journal of medicinal chemistry (17.07.2003)
Published in Journal of medicinal chemistry (17.07.2003)
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Rat Strain Differences in the Ability to Disrupt Sensorimotor Gating Are Limited to the Dopaminergic System, Specific to Prepulse Inhibition, and Unrelated to Changes in Startle Amplitude or Nucleus Accumbens Dopamine Receptor Sensitivity
Kinney, Gene G, Wilkinson, Lynn O, Saywell, Kay L, Tricklebank, Mark D
Published in The Journal of neuroscience (01.07.1999)
Published in The Journal of neuroscience (01.07.1999)
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Journal Article
Cognition-enhancing drugs increase stimulated hippocampal theta rhythm amplitude in the urethane-anesthetized rat
Kinney, G G, Patino, P, Mermet-Bouvier, Y, Starrett, Jr, J E, Gribkoff, V K
Published in The Journal of pharmacology and experimental therapeutics (01.10.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1999)
Journal Article
An instrumental method for long-term continuous REM sleep deprivation of neonatal rats
PINGFU FENG, VOGEL, G. W, OBERMEYER, W, KINNEY, G. G
Published in Sleep (New York, N.Y.) (15.03.2000)
Published in Sleep (New York, N.Y.) (15.03.2000)
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