Discovery of novel positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu 5)
Varnes, Jeffrey G., Marcus, Andrew P., Mauger, Russell C., Throner, Scott R., Hoesch, Valerie, King, Megan M., Wang, Xia, Sygowski, Linda A., Spear, Nathan, Gadient, Reto, Brown, Dean G., Campbell, James B.
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
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4-Aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators
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Published in Bioorganic & medicinal chemistry letters (15.12.2010)
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
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4-Piperidin-4-ylidenemethyl-benzamides as δ-opioid receptor agonists for CNS indications: Identifying clinical candidates
Dantzman, Cathy L., King, Megan M., Ernst, Glen E., Wang, Xia, McCauley, John P., Andisik, Donald W., Brush, Kelly, Bui, Khanh H., Frietze, William, Hoesch, Valerie, Liu, Jay, Palmer, William E., Spear, Nathan, Hudzik, Thomas J., Wesolowski, Steven S.
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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In vitro binding of a radio-labeled positive allosteric modulator for metabotropic glutamate receptor subtype 5
Zysk, John R., Spear, Nathan, Fieles, William, Stein, Mark M., Sygowski, Linda S., King, Megan M., Hoesch, Valerie, Hastings, Richard, Brockel, Becky, Do, Mylinh, Ström, Peter, Gadient, Reto, Chhajlani, Vijay, Elmore, Charles S., Maier, Donna L
Published in Synapse (New York, N.Y.) (01.03.2013)
Published in Synapse (New York, N.Y.) (01.03.2013)
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Multiparameter exploration of piperazine derivatives as δ-opioid receptor agonists for CNS indications
McCauley, John P., Dantzman, Cathy L., King, Megan M., Ernst, Glen E., Wang, Xia, Brush, Kelly, Palmer, William E., Frietze, William, Andisik, Donald W., Hoesch, Valerie, Doring, Kenneth, Hulsizer, James, Bui, Khanh H., Liu, Jay, Hudzik, Thomas J., Wesolowski, Steven S.
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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