Selective degradation of CDK6 by a palbociclib based PROTAC
Rana, Sandeep, Bendjennat, Mourad, Kour, Smit, King, Hannah M., Kizhake, Smitha, Zahid, Muhammad, Natarajan, Amarnath
Published in Bioorganic & medicinal chemistry letters (01.06.2019)
Published in Bioorganic & medicinal chemistry letters (01.06.2019)
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Journal Article
Dimers of isatin derived α-methylene-γ-butyrolactone as potent anti-cancer agents
Rana, Sandeep, Kour, Smit, Kizhake, Smitha, King, Hannah M., Mallareddy, Jayapal Reddy, Case, Adam J., Huxford, Tom, Natarajan, Amarnath
Published in Bioorganic & medicinal chemistry letters (01.06.2022)
Published in Bioorganic & medicinal chemistry letters (01.06.2022)
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Journal Article
Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax
King, Hannah M., Rana, Sandeep, Kubica, Sydney P., Mallareddy, Jayapal Reddy, Kizhake, Smitha, Ezell, Edward L., Zahid, Muhammad, Naldrett, Michael J., Alvarez, Sophie, Law, Henry C.-H., Woods, Nicholas T., Natarajan, Amarnath
Published in Bioorganic & medicinal chemistry letters (01.07.2021)
Published in Bioorganic & medicinal chemistry letters (01.07.2021)
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Journal Article
CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
Kour, Smit, Rana, Sandeep, Contreras, Jacob I, King, Hannah M, Robb, Caroline M, Sonawane, Yogesh A, Bendjennat, Mourad, Crawford, Ayrianne J, Barger, Carter J, Kizhake, Smitha, Luo, Xu, Hollingsworth, Michael A, Natarajan, Amarnath
Published in Molecular pharmacology (01.10.2019)
Published in Molecular pharmacology (01.10.2019)
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Synthesis and SAR studies of novel 1,2,4-oxadiazole-sulfonamide based compounds as potential anticancer agents for colorectal cancer therapy
Shamsi, Farheen, Hasan, Phool, Queen, Aarfa, Hussain, Afzal, Khan, Parvez, Zeya, Bushra, King, Hannah M., Rana, Sandeep, Garrison, Jered, Alajmi, Mohamed F., Rizvi, M. Moshahid Alam, Zahid, Muhammad, Imtaiyaz Hassan, Md, Abid, Mohammad
Published in Bioorganic chemistry (01.05.2020)
Published in Bioorganic chemistry (01.05.2020)
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Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth
Napoleon, John Victor, Sagar, Satish, Kubica, Sydney P, Boghean, Lidia, Kour, Smit, King, Hannah M, Sonawane, Yogesh A, Crawford, Ayrianne J, Gautam, Nagsen, Kizhake, Smitha, Bialk, Pawel A, Kmiec, Eric, Mallareddy, Jayapal Reddy, Patil, Prathamesh P, Rana, Sandeep, Singh, Sarbjit, Prahlad, Janani, Grandgenett, Paul M, Borgstahl, Gloria E O, Ghosal, Gargi, Alnouti, Yazen, Hollingsworth, Michael A, Radhakrishnan, Prakash, Natarajan, Amarnath
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2022)
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Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy
Contreras, Jacob I, Robb, Caroline M, King, Hannah M, Baxter, Jared, Crawford, Ayrianne J, Kour, Smit, Kizhake, Smitha, Sonawane, Yogesh A, Rana, Sandeep, Hollingsworth, Michael A, Luo, Xu, Natarajan, Amarnath
Published in ACS chemical biology (18.05.2018)
Published in ACS chemical biology (18.05.2018)
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‘English as an additional language’, ‘multilingual’, and ‘vulnerable’: a reflexive account of the labelling practices surrounding school pupils in a researcher-practitioner collaboration
Pérez Andrade, Gonzalo, King, Hannah M.
Published in Language and intercultural communication (05.07.2024)
Published in Language and intercultural communication (05.07.2024)
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